Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Santiago Partida-Sanchez"'
Autor:
Jaime D. Rhodes, Aishwarya Devaraj, Frank Robledo-Avila, Sabarathnam Balu, Lauren Mashburn-Warren, John R. Buzzo, Santiago Partida-Sanchez, Lauren O. Bakaletz, Steven D. Goodman
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105304- (2024)
Summary: Background: Bacterial biofilm communities are embedded in a protective extracellular matrix comprised of various components, with its' integrity largely owed to a 3-dimensional lattice of extracellular DNA (eDNA) interconnected by Holliday J
Externí odkaz:
https://doaj.org/article/ffb5dfa8a8bc4a86ad806433461c8c67
Autor:
Asmaa Badr, Mostafa Eltobgy, Kathrin Krause, Kaitlin Hamilton, Shady Estfanous, Kylene P. Daily, Arwa Abu Khweek, Ahmad Hegazi, Midhun N. K. Anne, Cierra Carafice, Frank Robledo-Avila, Youssra Saqr, Xiaoli Zhang, Tracey L. Bonfield, Mikhail A. Gavrilin, Santiago Partida-Sanchez, Stephanie Seveau, Estelle Cormet-Boyaka, Amal O. Amer
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Cystic fibrosis (CF) human and mouse macrophages are defective in their ability to clear bacteria such as Burkholderia cenocepacia. The autophagy process in CF (F508del) macrophages is halted, and the underlying mechanism remains unclear. Furthermore
Externí odkaz:
https://doaj.org/article/db95827f79284dbaa804f925acce7f81
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/859a309be79849488b8e83c2c9870dc1
Autor:
Frank H. Robledo-Avila, Juan de Dios Ruiz-Rosado, Santiago Partida-Sanchez, Kenneth L. Brockman
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Non-typeable Haemophilus influenzae (NTHi) causes multiple diseases of the human airway and is a predominant bacterial pathogen of acute otitis media and otitis media in which treatment fails. NTHi utilizes a system of phase variable epigenetic regul
Externí odkaz:
https://doaj.org/article/61b025c9e05c472eb965f8f45893b52f
Autor:
Kenneth L. Brockman, M. Taylor Branstool, John M. Atack, Frank Robledo-Avila, Santiago Partida-Sanchez, Michael P. Jennings, Lauren O. Bakaletz
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Nontypeable Haemophilus influenzae (NTHI) is the causative agent of multiple respiratory tract infections. Several human pathogens, including NTHI, possess a novel genetic system, termed the phasevarion, which mediates a rapid and reversible
Externí odkaz:
https://doaj.org/article/9b46a41b92a6434a906b238023a63cda
Autor:
Kyle Caution, Nicholas Young, Frank Robledo-Avila, Kathrin Krause, Arwa Abu Khweek, Kaitlin Hamilton, Asmaa Badr, Anup Vaidya, Kylene Daily, Hawin Gosu, Midhun N. K. Anne, Mostafa Eltobgy, Duaa Dakhlallah, Sudha Argwal, Shady Estfanous, Xiaoli Zhang, Santiago Partida-Sanchez, Mikhail A. Gavrilin, Wael N. Jarjour, Amal O. Amer
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Gout is characterized by attacks of arthritis with hyperuricemia and monosodium urate (MSU) crystal-induced inflammation within joints. Innate immune responses are the primary drivers for tissue destruction and inflammation in gout. MSU crystals enga
Externí odkaz:
https://doaj.org/article/5f9399b8f88346d990ae67891307c8ef
Autor:
Kyle A Jablonski, Stephanie A Amici, Lindsay M Webb, Juan de Dios Ruiz-Rosado, Phillip G Popovich, Santiago Partida-Sanchez, Mireia Guerau-de-Arellano
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145342 (2015)
Classically (M1) and alternatively activated (M2) macrophages exhibit distinct phenotypes and functions. It has been difficult to dissect macrophage phenotypes in vivo, where a spectrum of macrophage phenotypes exists, and also in vitro, where low or
Externí odkaz:
https://doaj.org/article/c3bea43b514049a2b49d50048f68fc6a
Autor:
Michael Bolton, Dennis J Horvath, Birong Li, Hanna Cortado, David Newsom, Peter White, Santiago Partida-Sanchez, Sheryl S Justice
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33897 (2012)
Despite the continually increasing rates of adverse perinatal outcomes across the globe, the molecular mechanisms that underlie adverse perinatal outcomes are not completely understood. Clinical studies report that 10% of pregnant women will experien
Externí odkaz:
https://doaj.org/article/c004f589cc954fbea9818b2842bebf1a
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51351 (2012)
Polyriboinosinic-polyribocytoidylic acid (pIC), a synthetic dsRNA, acts as an adjuvant that boosts immune responses and protection. Intranasal (IN) administration of pIC has recently been used to adjuvant influenza virus vaccines; however, the effect
Externí odkaz:
https://doaj.org/article/95c688e3019f4c70823f243b6655b449
Autor:
Mostafa M. Eltobgy, Ashley Zani, Adam D. Kenney, Shady Estfanous, Eunsoo Kim, Asmaa Badr, Cierra Carafice, Kylene Daily, Owen Whitham, Maciej Pietrzak, Amy Webb, Jeffrey Kawahara, Adrian C. Eddy, Parker Denz, Mijia Lu, Mahesh KC, Mark E. Peeples, Jianrong Li, Jian Zhu, Jianwen Que, Richard Robinson, Oscar Rosas Mejia, Rachael E. Rayner, Luanne Hall-Stoodley, Stephanie Seveau, Mikhail A. Gavrilin, Xiaoli Zhang, Jeronay Thomas, Jacob E. Kohlmeier, Mehul S. Suthar, Eugene Oltz, Andrea Tedeschi, Frank H. Robledo-Avila, Santiago Partida-Sanchez, Emily A. Hemann, Eman Abdelrazik, Adriana Forero, Shahid M. Nimjee, Prosper N. Boyaka, Estelle Cormet-Boyaka, Jacob S. Yount, Amal O. Amer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(21)
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2) is a worldwide health concern, and new treatment strategies are needed. Targeting inflammatory innate immunity pathways holds therapeutic promise, but effective molecular targets remain e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d41407d3800934f9acfc60d7cf1ba2d
https://pubmed.ncbi.nlm.nih.gov/35588457
https://pubmed.ncbi.nlm.nih.gov/35588457