Do we treat dementia of the Alzheimer type or Alzheimer's disease? Anti-dementia drugs in the era of biomarkers

Autor: Guido, Dorman, Santiago, O'Neill, Franco, Appiani, Ignacio, Flores, María Del Rosario, Chiesa, Florencia, Vallejos, Julian, Bustin

Publikováno v: Vertex (Buenos Aires, Argentina). 33(157)

Approved drug treatments for Alzheimer´s disease (AD) are symptomatic and don´t modify the disease course. These include acetylcholinesterase inhibitors (AchI) and N-methyl-D-aspartate receptor antagonist, memantine. Around 20 years ago, these drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::293b41082b6729843c836627ddebbbe1
https://pubmed.ncbi.nlm.nih.gov/36219187

Biomarkers for dementia in Latin American countries:Gaps and opportunities

Autor: Mario A. Parra, Paulina Orellana, Tomas Leon, Cabello G. Victoria, Fernando Henriquez, Rodrigo Gomez, Constanza Avalos, Andres Damian, Andrea Slachevsky, Agustin Ibañez, Henrik Zetterberg, Betty M. Tijms, Jennifer S. Yokoyama, Stefanie D. Piña‐Escudero, J. Nicholas Cochran, Diana L. Matallana, Daisy Acosta, Ricardo Allegri, Bianca P. Arias‐Suárez, Bernardo Barra, Maria Isabel Behrens, Sonia M. D. Brucki, Geraldo Busatto, Paulo Caramelli, Sheila Castro‐Suarez, Valeria Contreras, Nilton Custodio, Sergio Dansilio, Myriam De la Cruz‐Puebla, Leonardo Cruz de Souza, Monica M. Diaz, Lissette Duque, Gonzalo A. Farías, Sergio T. Ferreira, Nahuel Magrath Guimet, Ana Kmaid, David Lira, Francisco Lopera, Beatriz Mar Meza, Eliane C. Miotto, Ricardo Nitrini, Alberto Nuñez, Santiago O'Neill, John Ochoa, Maritza Pintado‐Caipa, Elisa de Paula França Resende, Shannon Risacher, Luz Angela Rojas, Valentina Sabaj, Lucas Schilling, Allis F. Sellek, Ana Sosa, Leonel T. Takada, Antonio L. Teixeira, Martha Unaucho‐Pilalumbo, Claudia Duran‐Aniotz

Publikováno v: Parra, M A, Orellana, P, Leon, T, Victoria, C G, Henriquez, F, Gomez, R, Avalos, C, Damian, A, Slachevsky, A, Ibañez, A, Zetterberg, H, Tijms, B M, Yokoyama, J S, Piña-Escudero, S D, Cochran, J N, Matallana, D L, Acosta, D, Allegri, R, Arias-Suárez, B P, Barra, B, Behrens, M I, Brucki, S M D, Busatto, G, Caramelli, P, Castro-Suarez, S, Contreras, V, Custodio, N, Dansilio, S, la Cruz-Puebla, M D, de Souza, L C, Diaz, M M, Duque, L, Farías, G A, Ferreira, S T, Guimet, N M, Kmaid, A, Lira, D, Lopera, F, Meza, B M, Miotto, E C, Nitrini, R, Nuñez, A, O'Neill, S, Ochoa, J, Pintado-Caipa, M, Resende, E D P F, Risacher, S, Rojas, L A, Sabaj, V, Schilling, L, Sellek, A F, Sosa, A, Takada, L T, Teixeira, A L, Unaucho-Pilalumbo, M & Duran-Aniotz, C 2022, ' Biomarkers for dementia in Latin American countries : Gaps and opportunities ', Alzheimer's and Dementia . https://doi.org/10.1002/alz.12757
Alzheimer's and Dementia. Elsevier

Limited knowledge on dementia biomarkers in Latin American and Caribbean (LAC) countries remains a serious barrier. Here, we reported a survey to explore the ongoing work, needs, interests, potential barriers, and opportunities for future studies rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3eb6423963b88f563b7d3d9628574a
https://research.vumc.nl/en/publications/b1a9b969-eed2-4817-8ede-1f679e06576a

[Juvenile myoclonic epilepsy and associated neurocognitive and executive dysfunctions]

Autor: Verónica, Campanille, Natalia, Sierra, Analía, Calle, Ricardo, Bernater, Alejandro, Thomson, Santiago, O'Neill

Publikováno v: Medicina. 81(6)

Juvenile myoclonic epilepsy (JME) is a benign disorder with a good response to antiepileptic drugs. Neuropsychological evaluations revealed mild cognitive deficits. The objective of this study is to determine the cognitive profile and mood symptoms i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::447be98f3b57c58f645e4a26cdc76897
https://pubmed.ncbi.nlm.nih.gov/34875595

Quality of life, mood, and cognitive performance in older adults with cognitive impairment during the first wave of COVID 19 in Argentina

Autor: Irina Aragón, Guido Dorman, Natalia Sierra Sanjurjo, Ignacio Flores, Santiago O'Neill, Galeno Rojas

Publikováno v: International Journal of Geriatric Psychiatry

Background and Objectives In Argentina, government has established lockdown on 19 March 2020 to decrease SARS‐COV‐2 infection. The study aim was to understand how mandatory quarantine imposed due to COVID‐19 pandemic has affected quality of lif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1127b8b9b54392f9c422228f9ed5bd65
https://pubmed.ncbi.nlm.nih.gov/34755917

How are medics approaching people with dementia in Latin America?

Autor: Pablo Richly, Pablo López, Santiago O'Neill, Daniel Flichtentrei

Publikováno v: International psychogeriatrics. 32(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3737097c906c7f3f9db481db5a50344c
https://pubmed.ncbi.nlm.nih.gov/31309915