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Therapeutic potential of a novel hybrid protein: Mitigating allergy and airway remodeling in chronic asthma models induced by Dermatophagoides pteronyssinus.

Autor: Fernandes AMS; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil. Electronic address: marciofernandes14@gmail.com., da Silva ES; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil; Post-Graduate Program in Immunology (PPGIm) of the Federal University of Bahia, Salvador, BA, Brazil. Electronic address: eduardossilva06@gmail.com., Silva RC; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil; Post-Graduate Program in Immunology (PPGIm) of the Federal University of Bahia, Salvador, BA, Brazil. Electronic address: raphaschagas@hotmail.com., Silveira EF; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil. Electronic address: elissfontess@gmail.com., Santiago LF; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil. Electronic address: leonardofsantiago@gmail.com., de Andrade Belitardo EMM; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil. Electronic address: emilia_mandrade@hotmail.com., Alves VDS; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil. Electronic address: alvesvitor@usp.br., Bôas DSV; Post-Graduate Program in Immunology (PPGIm) of the Federal University of Bahia, Salvador, BA, Brazil; Laboratory of Histotechnology, Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil. Electronic address: vilasboasdeise@gmail.com., de Freitas LAR; Gonçalo Moniz Institute, Oswaldo Cruz Foundation (FioCruz), Salvador, BA, Brazil; Department of Pathology and Forensic Medicine, School of Medicine, Federal University of Bahia, Salvador, BA, Brazil. Electronic address: freitas.luizar@gmail.com., Ferreira F; Department of Biosciences and Medical Biology, University of Salzburg, Salzburg, Austria. Electronic address: fatima.ferreira@sbg.ac.at., Jacquet A; Department of Biochemistry, Chulalongkorn University, Bangkok, Thailand. Electronic address: Alain.J@chula.ac.th., Pacheco LGC; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil. Electronic address: lgcpacheco@gmail.com., Alcantara-Neves NM; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil; Post-Graduate Program in Immunology (PPGIm) of the Federal University of Bahia, Salvador, BA, Brazil. Electronic address: neuzalcantara@gmail.com., Pinheiro CS; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil; Post-Graduate Program in Immunology (PPGIm) of the Federal University of Bahia, Salvador, BA, Brazil. Electronic address: carina.pinheiro@ufba.br.

Publikováno v: Molecular immunology [Mol Immunol] 2024 Oct 01; Vol. 175, pp. 121-131. Date of Electronic Publication: 2024 Oct 01.

The hybrid protein BTH2 suppresses allergic airway inflammation in a murine model of HDM-specific immunotherapy.

Autor: da Silva ES; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.; Post-Graduate Program in Biotechnology of the Northeast Biotechnology Network (RENORBIO), Maceió, Brazil., de Santana MBR; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.; Post-Graduate Program in Immunology, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil., Silveira EF; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil., Torres RT; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil., Silva RC; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.; Post-Graduate Program in Immunology, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil., Fernandes AMS; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil., Belitardo EMMA; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.; Post-Graduate Program in Immunology, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.; Gonçalo Moniz Institute, Oswaldo Cruz Foundation (FioCruz), Salvador, Brazil., Garcés LFS; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.; Post-Graduate Program in Immunology, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.; Faculty of Health Sciences, Technical University of Ambato, Ambato, Ecuador., Santiago LF; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil., Urrego JR; Department of Pharmacy, University of Cartagena, Cartagena, Colombia., Vilas-Bôas DS; Post-Graduate Program in Immunology, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.; Laboratory of Histotechnology, Department of Biomorphology, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil., de Freitas LAR; Gonçalo Moniz Institute, Oswaldo Cruz Foundation (FioCruz), Salvador, Brazil.; Department of Pathology of the School of Medicine, Federal University of Bahia, Salvador, Brazil., Zakzuk J; Institute of Immunological Research, University of Cartagena, Cartagena, Colombia., Pacheco LGC; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil., Cruz ÁA; ProAR Foundation and Federal University of Bahia, Salvador, Brazil., Ferreira F; Department of Biosciences, Paris-Lodron University of Salzburg, Salzburg, Austria., Cooper P; Institute of Infection and Immunity, St George's University of London, London, UK.; School of Medicine, International University of Ecuador, Quito, Ecuador., Caraballo L; Institute of Immunological Research, University of Cartagena, Cartagena, Colombia., Pinheiro CDS; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.; Post-Graduate Program in Immunology, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil., Alcantara-Neves NM; Laboratory of Allergology and Acarology (LAA), Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.; Post-Graduate Program in Biotechnology of the Northeast Biotechnology Network (RENORBIO), Maceió, Brazil.; Post-Graduate Program in Immunology, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.

Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2023 Aug; Vol. 53 (8), pp. 821-832. Date of Electronic Publication: 2023 Feb 13.

Engineering an optimized expression operating unit for improved recombinant protein production in Escherichia coli.

Autor: Santos SPO; Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil., Garcés LFS; Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil., Silva FSR; Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil., Santiago LF; Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil., Pinheiro CS; Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil., Alcantara-Neves NM; Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil., Pacheco LGC; Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil. Electronic address: luis.pacheco@ufba.br.

Publikováno v: Protein expression and purification [Protein Expr Purif] 2022 Nov; Vol. 199, pp. 106150. Date of Electronic Publication: 2022 Aug 06.

Neonatal Scn1b-null mice have sinoatrial node dysfunction, altered atrial structure, and atrial fibrillation.

Autor: Ramos-Mondragon R; Department of Pharmacology and., Edokobi N; Department of Pharmacology and., Hodges SL; Department of Pharmacology and., Wang S; Department of Pharmacology and., Bouza AA; Department of Pharmacology and., Canugovi C; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA., Scheuing C; Department of Pharmacology and., Juratli L; Department of Pharmacology and., Abel WR; Department of Pharmacology and., Noujaim SF; Department of Molecular Pharmacology & Physiology, University of South Florida College of Medicine, Tampa, Florida, USA., Madamanchi NR; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA., Runge MS; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA., Lopez-Santiago LF; Department of Pharmacology and., Isom LL; Department of Pharmacology and.; Department of Neurology and.; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.

Publikováno v: JCI insight [JCI Insight] 2022 May 23; Vol. 7 (10). Date of Electronic Publication: 2022 May 23.