Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Santiago Hernández-Pérez"'
Autor:
Joana Silva, Ferhat Alkan, Sofia Ramalho, Goda Snieckute, Stefan Prekovic, Ana Krotenberg Garcia, Santiago Hernández-Pérez, Rob van der Kammen, Danielle Barnum, Liesbeth Hoekman, Maarten Altelaar, Wilbert Zwart, Saskia Jacoba Elisabeth Suijkerbuijk, Simon Bekker-Jensen, William James Faller
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Intestinal stem cells are responsible for replenishing cells within the high-turnover intestinal epithelium. Here they show that ribosome dynamics affect intestinal stem cell identity through a mechanism that is triggered by changes in nutrient avail
Externí odkaz:
https://doaj.org/article/e5d3a0beb6bb494d83b16a5ab563b7a2
Autor:
Santiago Hernández-Pérez, Elisa Cabrera, Hugo Amoedo, Sara Rodríguez-Acebes, Stephane Koundrioukoff, Michelle Debatisse, Juan Méndez, Raimundo Freire
Publikováno v:
Molecular Oncology, Vol 10, Iss 8, Pp 1196-1206 (2016)
DNA replication control is a key process in maintaining genomic integrity. Monitoring DNA replication initiation is particularly important as it needs to be coordinated with other cellular events and should occur only once per cell cycle. Crucial pla
Externí odkaz:
https://doaj.org/article/77d7e8ffcbcd4be680be513156e9b11a
Autor:
Esperanza Hernández-Carralero, Elisa Cabrera, Ignacio Alonso-de Vega, Santiago Hernández-Pérez, Veronique A. J. Smits, Raimundo Freire
Publikováno v:
Cells, Vol 7, Iss 10, p 146 (2018)
Eukaryotic cells divide by accomplishing a program of events in which the replication of the genome is a fundamental part. To ensure all cells have an accurate copy of the genome, DNA replication occurs only once per cell cycle and is controlled by n
Externí odkaz:
https://doaj.org/article/244f89b056234a95949c4fb57b81d835
Autor:
Inés Paniagua, Zainab Tayeh, Mattia Falcone, Santiago Hernández Pérez, Aurora Cerutti, Jacqueline J. L. Jacobs
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
MAD2L2 – as a member of the shieldin complex - counteracts resection during DNA repair. Here the authors demonstrate that MAD2L2 protects stalled replication forks from excessive resection, in a shieldin-independent and REV3L-dependent manner.
Externí odkaz:
https://doaj.org/article/a9b173c02d504a909a58c98740cb0626
Autor:
Ferhat Alkan, Oscar G Wilkins, Santiago Hernández-Pérez, Sofia Ramalho, Joana Silva, Jernej Ule, William J Faller
Publikováno v:
Alkan, F, Wilkins, O G, Hernández-Pérez, S, Ramalho, S, Silva, J, Ule, J & Faller, W J 2022, ' Identifying ribosome heterogeneity using ribosome profiling ', Nucleic Acids Research, vol. 50, no. 16, pp. e95 . https://doi.org/10.1093/nar/gkac484
Recent studies have revealed multiple mechanisms that can lead to heterogeneity in ribosomal composition. This heterogeneity can lead to preferential translation of specific panels of mRNAs, and is defined in large part by the ribosomal protein (RP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d302d8bf12113a0038b671c3bca954a2
https://kclpure.kcl.ac.uk/en/publications/69391a34-d84b-47e0-9cd8-3163c5f0da0f
https://kclpure.kcl.ac.uk/en/publications/69391a34-d84b-47e0-9cd8-3163c5f0da0f
Autor:
Inés Paniagua, Zainab Tayeh, Mattia Falcone, Santiago Hernández Pérez, Aurora Cerutti, Jacqueline J. L. Jacobs
Publikováno v:
Nature communications. 13(1)
Protection of stalled replication forks is essential to prevent genome instability, a major driving force of tumorigenesis. Several key regulators of DNA double-stranded break (DSB) repair, including 53BP1 and RIF1, have been implicated in fork prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aadf7e171f61328605ed56b62614ac0c
https://pubmed.ncbi.nlm.nih.gov/36075897
https://pubmed.ncbi.nlm.nih.gov/36075897
Autor:
Inge de Krijger, Bastian Föhr, Santiago Hernández Pérez, Estelle Vincendeau, Judit Serrat, Alexander Marc Thouin, Vivek Susvirkar, Chloé Lescale, Inés Paniagua, Liesbeth Hoekman, Simranjeet Kaur, Maarten Altelaar, Ludovic Deriano, Alex C. Faesen, Jacqueline J. L. Jacobs
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
MAD2L2 — a member of the shieldin complex — is known to play important roles in DNA repair. Here the authors demonstrate how MAD2L2 dimerization mediated through SHLD2 participates in shieldin assembly and function.
Externí odkaz:
https://doaj.org/article/ff52d6b334fd4c1a8c8a1c74813d0adb