Výsledky vyhledávání - "Santiago Grisolia"

Elektronická kniha

Cirrhosis, Hepatic Encephalopathy, and Ammonium Toxicity

Autor: Santiago Grisolía, Vicente Felipo, Maria-Dolores Miñana

Proceedings of an international symposium held in Valencia, Spain, November 27--29, 1989

Glutamate Induces a Calcineurin-Mediated Dephosphorylation of Na+,K+-ATPase that Results in Its Activation in Cerebellar Neurons in Culture

Autor: Elena Kosenko, Goizane Marcaida, María-Dolores Miñana, Vicente Felipo, Santiago Grisolia

Publikováno v: Europe PubMed Central
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In primary cultures of cerebellar neurons glutamate neurotoxicity is mainly mediated by activation of the NMDA receptor, which allows the entry of Ca2+ and Na+ into the neuron. To maintain Na+ homeostasis, the excess Na+ entering through the ion chan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7aa1a8c25c0cb33b551d426a2d43bc8
https://doi.org/10.1046/j.1471-4159.1996.66010099.x

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Elektronická kniha

Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy

Autor: Santiago Grisolía, Vicente Felipo

This volume contains the papers presented in the International Summer Course on'Cirrhosis, Hyperammonemia and Hepatic Encephalopathy,'which was one of the prestigious Summer Course, of the Complutense University of Madrid held in EI Escorial, Spain,

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Elektronická kniha

Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity

Autor: Vicente Felipo, Santiago Grisolía

This volume contains the papers presented at the International Symposium on'Cirrhosis, Hyperammonemia and Hepatic Encephalopathy', held in Valencia, Spain, January 24th-27th, 1994. Liver cirrhosis and other hepatic dysfunctions such as fulminant hepa

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Autor: Carmina Montoliu, Carlos Hermenegildo, Elena Kosenko, María-Dolores Miñana, Goizane Marcaida, Santiago Grisolia, Vicente Felipo

Publikováno v: Cellular and Molecular Neurobiology. 17:433-445

1. Previous results suggest that glutamine synthesis in brain could be modulated by nitrix oxide. The aim of this work was to assess this possibility.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5fd328e636d900daffa1867f1a2cb250
https://doi.org/10.1023/a:1026339428059

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NMDA Receptor antagonists prevent acute ammonia toxicity in mice

Autor: Goizane Marcaida, Santiago Grisolia, Vicente Felipo, Carmina Montoliu, Carlos Hermenegildo, María-Dolores Miñana

Publikováno v: Neurochemical Research. 21:1237-1244

We proposed that acute ammonia toxicity is mediated by activation of NMDA receptors. To confirm this hypothesis we have tested whether different NMDA receptor antagonists, acting on different sites of NMDA receptors, prevent death of mice induced by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039872937970662882c17044b5bc2cef
https://doi.org/10.1007/bf02532401

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Protein kinase C isoforms and cell proliferation in neuroblastoma cells

Autor: Eugenio Grau, María-Dolores Miñana, Santiago Grisolia, Vicente Felipo, Hugo Cabedo

Publikováno v: Molecular Brain Research. 37:125-133

The expression of protein kinase C isoforms in the neuroblastoma cell line Neuro 2a has been studied. It is shown that Neuro 2a cells express alpha, delta, epsilon and zeta PKCs. Inhibition of cell proliferation by using protein kinase C inhibitors (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57631877c371d7b3833aa58c8e1e103
https://doi.org/10.1016/0169-328x(95)00290-9

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Prenatal Exposure of Rats to Ammonia Impairs NMDA Receptor Function and Affords Delayed Protection Against Ammonia Toxicity and Glutamate Neurotoxicity

Autor: Goizane Marcaida, Vicente Felipo, María-Dolores Miñana, Santiago Grisolia

Publikováno v: Europe PubMed Central

The aim of this work was to assess whether perinatal hyperammonemia impairs the function of NMDA receptors and whether this impairment affords protection against acute ammonia toxicity and glutamate and NMDA neurotoxicity. Rats were exposed to ammoni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b62a859ec2f607b264c2e9cf3d29d8
https://doi.org/10.1097/00005072-199509000-00005

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Nitroarginine, an inhibitor of nitric oxide synthetase, attenuates ammonia toxicity and ammonia-induced alterations in brain metabolism

Autor: Elena Kosenko, Yuri Kaminsky, Santiago Grisolia, Vicente Felipo, María-Dolores Miñana, Eugenio Grau

Publikováno v: Neurochemical Research. 20:451-456

We have proposed that acute ammonia toxicity is mediated by activation of the N-methyl-D-aspartate type of glutamate receptors. MK-801, a selective antagonist of these receptors, prevents death of animals induced by acute ammonia intoxication as well

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252c3bcfe814cb9554e2937919cceb09
https://doi.org/10.1007/bf00973101

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L-Carnitine increases the affinity of glutamate for quisqualate receptors and prevents glutamate neurotoxicity

Autor: Santiago Grisolia, Vicente Felipo, Hugo Cabedo, María-Dolores Miñana

Publikováno v: Neurochemical Research. 19:373-377

We have shown that acute ammonia toxicity is mediated by activation of the NMDA type of glutamate receptors. Although it is well known that L-carnitine prevents acute ammonia toxicity, the underlying molecular mechanism is not clear. We suspected tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5153e48844f84360c12552b42ba2eca8
https://doi.org/10.1007/bf00971588

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