GECOP-MMC: phase IV randomized clinical trial to evaluate the efficacy of hyperthermic intraperitoneal chemotherapy (HIPEC) with mytomicin-C after complete surgical cytoreduction in patients with colon cancer peritoneal metastases

Autor: Fernando Pereira, Angel Serrano, Israel Manzanedo, Estibalitz Pérez-Viejo, Santiago González-Moreno, Luis González-Bayón, Alvaro Arjona-Sánchez, Juan Torres, Isabel Ramos, Maria E. Barrios, Pedro Cascales, Rafael Morales, Enrique Boldó, Alfonso García-Fadrique, Xabier Arteaga, Alberto Gutierrez-Calvo, Susana Sánchez-García, Enrique Asensio, Cesar P. Ramírez, Manuel Artiles, Javier Vaqué, Pedro A. Parra, Pedro Villarejo, Cristóbal Muñoz-Casares, Estrella Turienzo, Alicia Calero, Isabel Jaén Torrejimeno, Isabel Prieto, Julio Galindo, Vicente Borrego, Manuel E. Marcello, Cristina Rihuete, Joaquin Carrasco, Luis Gomez-Quiles

Publikováno v: BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)

Abstract Background The French PRODIGE 7 trial, published on January 2021, has raised doubts about the specific survival benefit provided by HIPEC with oxaliplatin 460 mg/m2 (30 minutes) for the treatment of peritoneal metastases from colorectal canc

Externí odkaz: https://doaj.org/article/0ea95b90f8f840e4862d548b694593da

The impact of PRODIGE 7 on the current worldwide practice of CRS-HIPEC for colorectal peritoneal metastases: A web-based survey and 2021 statement by Peritoneal Surface Oncology Group International (PSOGI)

Autor: Brendan Moran, John Spiliotis, Paul H. Sugarbaker, Claudio Almeida Quadros, Yutaka Yonemura, Santiago González-Moreno, Yan Li, Vincent C J van de Vlasakker, Marcello Deraco, Robin J. Lurvink, Wim Ceelen, Kuno Lehmann, Ignace H. J. T. de Hingh, Melissa Ching Ching Teo, David L. Morris, S.P. Somashekhar, Kurt Van der Speeten, Vic J. Verwaal, Antonio Sommariva, Olivier Glehen, Peter H Cashin, Beate Rau, Pompiliu Piso, Diane Goéré

Publikováno v: European Journal of Surgical Oncology, 47(11), 2888-2892. ELSEVIER SCI LTD
van de Vlasakker, V C J, Lurvink, R J, Cashin, P H, Ceelen, W, Deraco, M, Goéré, D, González-Moreno, S, Lehmann, K, Li, Y, Moran, B, Morris, D L, Piso, P, Quadros, C A, Rau, B, Somashekhar, S P, Sommariva, A, van der Speeten, K, Spiliotis, J, Sugarbaker, P H, Teo, M C C, Verwaal, V J, Yonemura, Y, Glehen, O & de Hingh, I H J T 2021, ' The impact of PRODIGE 7 on the current worldwide practice of CRS-HIPEC for colorectal peritoneal metastases : A web-based survey and 2021 statement by Peritoneal Surface Oncology Group International (PSOGI) ', European Journal of Surgical Oncology, vol. 47, no. 11, pp. 2888-2892 . https://doi.org/10.1016/j.ejso.2021.05.023

Introduction: The PRODIGE 7-trial investigated the additional value of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) to cytoreductive surgery (CRS) for patients with colorectal peritoneal metastases (CPM). The results of PRODIGE 7 were presented

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b0527b75136cdc9e398df26b5d24bd
https://doi.org/10.1016/j.ejso.2021.05.023

Prioritization, patient selection, and multimodal perioperative management of colorectal cancer facing health-care system saturation

Autor: Javier Galipienzo-Garcia, Oscar Alonso, Gloria Ortega-Pérez, Irene López-Rojo, Santiago González-Moreno

Publikováno v: Cirugía y Cirujanos, Vol 89, Iss 6 (2021)

The aim is to analyze the usefulness of pre-operative COVID-19 screening to detect asymptomatic patients, the capability of our patient selection algorithm to detect patients with more advanced tumors and the results of colorectal cancer surgery mana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b57bb9bfc5e1d1765055404834fa18
https://doi.org/10.24875/ciru.20000990

Survival outcomes in patients aged 75 years and over with peritoneal colorectal carcinomatosis after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC): multicenter study of the Spanish Group of Peritoneal Cancer Surgery (GECOP)

Autor: L. Gonzalez-Bayon, P. Barrios, Fernando Pereira, R. Morales, J. Torres-Melero, F.C. Muñoz-Casares, José Francisco López Gil, Santiago González-Moreno, Victor Lopez-Lopez, P. Bretcha-Boix, P.A. Cascales-Campos, A Arjona

Publikováno v: Clinical and Translational Oncology. 22:130-136

The attitude toward cytoreductive surgery with HIPEC in peritoneal carcinomatosis from colorectal cancer is unclear. The aim of this study is to report the perioperative outcomes after cytoreductive surgery with HIPEC in patients ≥ 75 years. This r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795a9d378fff5b54e58a4e392161ea03
https://doi.org/10.1007/s12094-019-02124-9

Techniques and Safety Issues for Intraperitoneal Chemotherapy

Autor: Javier Galipienzo-Garcia, Santiago González-Moreno, Gloria Ortega-Pérez, David Salvatierra-Díaz, O. Alonso-Casado, Manuel J. Linero-Noguera

Publikováno v: Surgical Oncology Clinics of North America. 27:495-506

Different techniques for delivering perioperative intraperitoneal chemotherapy have been described, but no significant differences have been found among them. Hyperthermic intraperitoneal chemotherapy (HIPEC) is a safe treatment for the patient and f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5440f14769103fd0a7d00df858796f
https://doi.org/10.1016/j.soc.2018.02.005