Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Santiago G. Lago"'
Autor:
Jihan K. Zaki, Santiago G. Lago, Nitin Rustogi, Shiral S. Gangadin, Jiri Benacek, Geertje F. van Rees, Frieder Haenisch, Jantine A. Broek, Paula Suarez-Pinilla, Tillmann Ruland, Bonnie Auyeung, Olya Mikova, Nikolett Kabacs, Volker Arolt, Simon Baron-Cohen, Benedicto Crespo-Facorro, Hemmo A. Drexhage, Lot D. de Witte, René S. Kahn, Iris E. Sommer, Sabine Bahn, Jakub Tomasik
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract A significant proportion of the personal and economic burden of schizophrenia can be attributed to the late diagnosis or misdiagnosis of the disorder. A novel, objective diagnostic approaches could facilitate the early detection and treatmen
Externí odkaz:
https://doaj.org/article/c80de718941446dfb6c9665174400e1e
Autor:
Santiago G. Lago, Sabine Bahn
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract There have been no new drugs for the treatment of schizophrenia in several decades and treatment resistance represents a major unmet clinical need. The drugs that exist are based on serendipitous clinical observations rather than an evidence
Externí odkaz:
https://doaj.org/article/59d4792cbc034f64a719463667d411af
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Mental health disorders are a leading cause of disability worldwide. Challenges such as disease heterogeneity, incomplete characterization of the targets of existing drugs and a limited understanding of functional interactions of complex gen
Externí odkaz:
https://doaj.org/article/66a0a34b91a84bf5bfe9d2b113ad006f
Autor:
Jakub Tomasik, Sung Yeon Sarah Han, Giles Barton-Owen, Dan-Mircea Mirea, Nayra A. Martin-Key, Nitin Rustogi, Santiago G. Lago, Tony Olmert, Jason D. Cooper, Sureyya Ozcan, Pawel Eljasz, Grégoire Thomas, Robin Tuytten, Tim Metcalfe, Thea S. Schei, Lynn P. Farrag, Lauren V. Friend, Emily Bell, Dan Cowell, Sabine Bahn
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The vast personal and economic burden of mood disorders is largely caused by their under- and misdiagnosis, which is associated with ineffective treatment and worsening of outcomes. Here, we aimed to develop a diagnostic algorithm, based on
Externí odkaz:
https://doaj.org/article/23a9d94e84ef46348bd37f43a26f3087
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Translational Psychiatry
Translational Psychiatry
Funder: Stanley Medical Research Institute (SMRI); doi: https://doi.org/10.13039/100007123
Mental health disorders are a leading cause of disability worldwide. Challenges such as disease heterogeneity, incomplete characterization of the targets
Mental health disorders are a leading cause of disability worldwide. Challenges such as disease heterogeneity, incomplete characterization of the targets
Autor:
Paula Suárez-Pinilla, Jordan M. Ramsey, Bonnie Auyeug, Volker Arolt, Jantine A. C. Broek, Tillmann Ruland, Marina Rubey, Olya Mikova, Javier Vázquez-Bourgon, Sergi Papiol, Frieder Haenisch, Sabine Bahn, Emiliano Gonzalez-Vioque, Santiago G. Lago, Geertje F. van Rees, Nikolett Kabacs, Jakub Tomasik, Benedicto Crespo-Facorro, Simon Baron-Cohen
Publikováno v:
Brain, Behavior, and Immunity. Volume 91, January 2021, Pages 673-682
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recent evidence suggests that comorbidities between neuropsychiatric conditions and metabolic syndrome may precede and even exacerbate long-term side-effects of psychiatric medication, such as a higher risk of type 2 diabetes and cardiovascular disea
Autor:
Nitin Rustogi, Jakub Tomasik, Emily K. Bell, Nayra A Martin-Key, Sabine Bahn, Grégoire Thomas, Sureyya Ozcan, Robin Tuytten, Dan Cowell, Jason D. Cooper, Santiago G. Lago, Tim Metcalfe, Pawel Eljasz, Lauren V. Friend, Sung Yeon Sarah Han, Dan-Mircea Mirea, Tony Olmert, Thea Sofie Schei, Lynn P. Farrag, Giles Barton-Owen
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Translational Psychiatry
Translational Psychiatry
The vast personal and economic burden of mood disorders is largely caused by their under- and misdiagnosis, which is associated with ineffective treatment and worsening of outcomes. Here, we aimed to develop a diagnostic algorithm, based on an online
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794f0df223e28101d5de5bf372224af4
https://www.repository.cam.ac.uk/handle/1810/318516
https://www.repository.cam.ac.uk/handle/1810/318516
Autor:
Jordan M. Ramsey, Frieder Haenisch, Olya Mikova, Bonnie Auyeug, Jantine A. C. Broek, Tillmann Ruland, Simon Baron-Cohen, Jakub Tomasik, Nikolett Kabacs, Jason D. Cooper, Paula Suárez-Pinilla, Volker Arolt, Geertje F. van Rees, Santiago G. Lago, Benedicto Crespo-Facorro, Sabine Bahn
Publikováno v:
Lago, S G, Tomasik, J, van Rees, G F, Ramsey, J M, Haenisch, F, Cooper, J D, Broek, J A, Suarez-Pinilla, P, Ruland, T, Auyeung, B, Mikova, O, Kabacs, N, Arolt, V, Baron-Cohen, S, Crespo-Facorro, B & Bahn, S 2018, ' Exploring the neuropsychiatric spectrum using high-content functional analysis of single-cell signaling networks ', Molecular Psychiatry, pp. 1-18 . https://doi.org/10.1038/s41380-018-0123-4
Neuropsychiatric disorders overlap in symptoms and share genetic risk factors, challenging their current classification into distinct diagnostic categories. Novel cross-disorder approaches are needed to improve our understanding of the heterogeneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff30939d496f4cd0b4b3a51cfd107b9
https://www.repository.cam.ac.uk/handle/1810/292585
https://www.repository.cam.ac.uk/handle/1810/292585
Autor:
Grégoire Thomas, Giles Barton-Owen, Jason D. Cooper, Jakub Tomasik, Lauren V. Friend, Tony Olmert, Robin Tuytten, Lynn P. Farrag, Sabine Bahn, Dan Cowell, Pawel Eljasz, Santiago G. Lago, Sureyya Ozcan, Sung Yeon Sarah Han, Nitin Rustogi, Emily K. Bell
Publikováno v:
Brain, behavior, and immunity. 90
With less than half of patients with major depressive disorder (MDD) correctly diagnosed within the primary care setting, there is a clinical need to develop an objective and readily accessible test to enable earlier and more accurate diagnosis. The
Autor:
Santiago G, Lago, Sabine, Bahn
Publikováno v:
NPJ genomic medicine. 7(1)
There have been no new drugs for the treatment of schizophrenia in several decades and treatment resistance represents a major unmet clinical need. The drugs that exist are based on serendipitous clinical observations rather than an evidence-based un