Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Santiago Diaz-Moralli"'
Autor:
Míriam Tarrado-Castellarnau, Santiago Diaz-Moralli, Ibrahim H. Polat, Rebeca Sanz-Pamplona, Cristina Alenda, Víctor Moreno, Antoni Castells, Marta Cascante
Publikováno v:
Translational Medicine Communications, Vol 2, Iss 1, Pp 1-9 (2017)
Abstract Background Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an essential regulator of glycolysis used as a housekeeping marker for gene/protein normalisation. Given the pivotal role of GAPDH in tumour metabolism, our aim was to correlate
Externí odkaz:
https://doaj.org/article/99bd00c6b6c84226bcc7b8d84a205cae
Autor:
Santiago Diaz-Moralli, Miriam Tarrado-Castellarnau, Cristina Alenda, Antoni Castells, Marta Cascante
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25323 (2011)
BackgroundTransketolase-like 1 (TKTL1) induces glucose degradation through anaerobic pathways, even in presence of oxygen, favoring the malignant aerobic glycolytic phenotype characteristic of tumor cells. As TKTL1 appears to be a valid biomarker for
Externí odkaz:
https://doaj.org/article/fa2a4f27dd9e48b28dc1ded8bb902bbd
Publikováno v:
Pharmacology & Therapeutics. 138:255-271
Cell proliferation is an essential mechanism for growth, development and regeneration of eukaryotic organisms; however, it is also the cause of one of the most devastating diseases of our era: cancer. Given the relevance of the processes in which cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe62beff1673f973f260f89fe0cbb17a
https://doi.org/10.1016/j.pharmthera.2013.01.011
https://doi.org/10.1016/j.pharmthera.2013.01.011
Autor:
Peter Carmeliet, Timothy M. Thomson, Leen Notebaert, Maciek R. Antoniewicz, Marta Cascante, Mieke Dewerchin, Johannes F. Coy, Guy Eelen, Óscar Meca-Cortés, Esther Aguilar, Santiago Diaz-Moralli, Bart Ghesquière, Silvia Marin
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Oncotarget
instname
Oncotarget
Metabolic reprogramming, a crucial cancer hallmark, shifts metabolic pathways such as glycolysis, tricarboxylic acid cycle or lipogenesis, to enable the growth characteristics of cancer cells. Here, we provide evidence that transketolase-like 1 (TKTL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7dc5808608f9e2838e7e20e486749d
http://hdl.handle.net/10261/160079
http://hdl.handle.net/10261/160079
Autor:
Federico P. Gómez, Josep Roca, Gema Alcarraz-Vizán, Francesco Falciani, Michelle A.C. Reed, Diego A. Rodríguez, Marta Cascante, Santiago Diaz-Moralli, Ulrich L. Günther
Publikováno v:
Metabolomics. 8:508-516
The study examines plasma metabolic profiles of patients with chronic obstructive pulmonary disease (COPD) to prove whether the disease influences metabolism at rest and after endurance training. This is based on the hypothesis that metabolome levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eccc3c36c31d7520005dc3a6067ae014
https://doi.org/10.1007/s11306-011-0336-x
https://doi.org/10.1007/s11306-011-0336-x
Autor:
Gema Alcarraz-Vizán, Pedro Vizán, Olga N. Solovjeva, Marta Cascante, Wilma M. Frederiks, Santiago Diaz-Moralli
Publikováno v:
International Journal of Cancer. 124:2789-2796
Cell cycle regulation is dependent on multiple cellular and molecular events. Cell proliferation requires metabolic sources for the duplication of DNA and cell size. However, nucleotide reservoirs are not sufficient to support cell duplication and, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9486a7a9acb7e4828c206df43f696b71
https://doi.org/10.1002/ijc.24262
https://doi.org/10.1002/ijc.24262
Autor:
Olga Jáuregui, Miriam Zanuy, Gema Alcarraz-Vizán, Juan Carlos Rodríguez-Prados, Marta Cascante, Josep J. Centelles, Pedro Vizán, Santiago Diaz-Moralli
Publikováno v:
Analytical Chemistry. 79:5000-5005
The quantitative understanding of the role of sugar phosphates in regulating tumor energetic metabolism at the proteomic and genomic level is a prerequisite for an efficient rational design in combined drug chemotherapy. Therefore, it is necessary to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997e07c46307b5bb1669048b272580cb
https://doi.org/10.1021/ac070170v
https://doi.org/10.1021/ac070170v
Autor:
Marta Cascante, Gema Alcarraz-Vizán, Santiago Diaz-Moralli, Jaime Rubio-Martinez, Cristian Obiol-Pardo
Publikováno v:
Journal of molecular graphicsmodelling. 49
Glucose-6-phosphate dehydrogenase (G6PDH) is an essential enzyme involved in the first reaction of the oxidative branch of the pentose phosphate pathway (PPP). Recently, G6PDH was suggested as a novel target protein for cancer therapy as one of the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c6e534f9417072420b1769923f5bfa
https://pubmed.ncbi.nlm.nih.gov/24637073
https://pubmed.ncbi.nlm.nih.gov/24637073
Autor:
Juan Casado-Vela, Elsa Sanchez-Lopez, Laura Menchén, Marta Cascante, Juan Carlos Lacal, Teresa Gómez del Pulgar, Arancha Cebrián, Santiago Diaz-Moralli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fb30e57c3be242c44548e6ba1135d75
https://doi.org/10.1017/cbo9780511996634.004
https://doi.org/10.1017/cbo9780511996634.004
Autor:
Victor Segura, Alberto Elosegui-Artola, Jose A. Martinez-Climent, Santiago Diaz-Moralli, Miguel Lafarga, Jose L. Fernandez-Luna, Lorena Nogueira, Jose L. Orgaz, Juan Martino, Patricia Ruiz-Ontañon, Marta Cascante, Alfonso Vázquez-Barquero, Azucena Esparís-Ogando, Atanasio Pandiella, Maria T. Berciano, Victoria Sanz-Moreno, Juan A. Montero, Beatriz Aldaz, Lara Grande
Publikováno v:
Stem cells (Dayton, Ohio). 31(6)
Glioblastoma (GBM) is associated with infiltration of peritumoral (PT) parenchyma by isolated tumor cells that leads to tumor regrowth. Recently, GBM stem-like or initiating cells (GICs) have been identified in the PT area, but whether these GICs hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074431480582d99bb4a3756b944b5afd
https://pubmed.ncbi.nlm.nih.gov/23401361
https://pubmed.ncbi.nlm.nih.gov/23401361