Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Santiago B. Rompani"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118514 (2015)
The numerous connections between neuronal cell bodies, made by their dendrites and axons, are vital for information processing in the brain. While dendrites and synapses have been extensively studied, axons have remained elusive to a large extent. We
Externí odkaz:
https://doaj.org/article/e7deddc0a16449fba7c6f51744489a3a
Autor:
Josephine Juettner, Daniel Hillier, Gergely Katona, Santiago B. Rompani, Michele Fiscella, Andreas Hierlemann, Antonia Drinnenberg, Balázs Rózsa, Zoltan Raics, Stuart Trenholm, Botond Roska
Publikováno v:
Nature neuroscience
Nature Neuroscience
Nature Neuroscience
How neuronal computations in the sensory periphery contribute to computations in the cortex is not well understood. We examined this question in the context of visual-motion processing in the retina and primary visual cortex (V1) of mice. We disrupte
Autor:
Thierry Azoulay, Zoltán Nagy, Federico Esposti, Hendrik P. N. Scholl, Arnold Szabo, Cameron S. Cowan, Pascal W. Hasler, Santiago B. Rompani, Kun-Chao Wu, Xiao-Long Fang, Ákos Lukáts, Tamas Szikra, Péter Hantz, Lue Xiang, Zi-Bing Jin, Rozina I. Hajdú, Josephine Juettner, Arjun Bharioke, Claudia P Patino-Alvarez, Jacek Krol, Dirk Schübeler, János Németh, Brigitte Gross-Scherf, Akos Kusnyerik, Rei K. Morikawa, Rong-Han Wu, Botond Roska, Arnaud R Krebs, Oezkan Keles, Dominik Hartl, David Goldblum
Publikováno v:
Nature Neuroscience
SummaryTargeting genes to specific neuronal or glial cell types is valuable both for understanding and for repairing brain circuits. Adeno-associated viral vectors (AAVs) are frequently used for gene delivery, but targeting expression to specific cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dece259d455bb946c5b268e7ec2f331d
Autor:
Keisuke Yonehara, Chiara N. Roth, Santiago B. Rompani, Fiona E. Müllner, Botond Roska, Chi Zhang, Adrian A. Wanner
Publikováno v:
Neuron
Rompani, S B, Müllner, F E, Wanner, A, Zhang, C, Roth, C N, Yonehara, K & Roska, B 2017, ' Different Modes of Visual Integration in the Lateral Geniculate Nucleus Revealed by Single-Cell-Initiated Transsynaptic Tracing ', Neuron, vol. 93, no. 4, pp. 767-776.e6 . https://doi.org/10.1016/j.neuron.2017.01.028
Rompani, S B, Müllner, F E, Wanner, A, Zhang, C, Roth, C N, Yonehara, K & Roska, B 2017, ' Different Modes of Visual Integration in the Lateral Geniculate Nucleus Revealed by Single-Cell-Initiated Transsynaptic Tracing ', Neuron, vol. 93, no. 4, pp. 767-776.e6 . https://doi.org/10.1016/j.neuron.2017.01.028
Summary The thalamus receives sensory input from different circuits in the periphery. How these sensory channels are integrated at the level of single thalamic cells is not well understood. We performed targeted single-cell-initiated transsynaptic tr
Publikováno v:
Journal of Neurophysiology. 112:3125-3137
In the central nervous system, inhibition shapes neuronal excitation. In spinal cord glycinergic inhibition predominates, whereas GABAergic inhibition predominates in the brain. The retina uses GABA and glycine in approximately equal proportions. Gly
Autor:
Tess A. Linden, Hopi E. Hoekstra, Brant K. Peterson, Clifford J. Tabin, Richard Borowsky, Masato Yoshizawa, Santiago B. Rompani, Nicolas Rohner, Johanna E. Kowalko, Jesse N. Weber, William R. Jeffery, Emily H. Kay
Publikováno v:
Current Biology. 23(19):1874-1883
Summary Background: Surface populations of Astyanax mexicanus, living in rivers like their common ancestors, school, while several, independently derived cave populations of the same species have lost schooling behavior. Results: We quantify schoolin
Autor:
Jing Zhou, Sarah Gondela, Annouck Luyten, Ying Chen, Santiago B. Rompani, Ayumi Takakura, Xuefeng Su
Publikováno v:
Journal of the American Society of Nephrology. 21:1521-1532
Mutations in PKD1, which encodes polycystin-1 (PC1), contribute to >85% of cases of autosomal dominant polycystic kidney disease (ADPKD). The planar cell polarity (PCP) pathway is necessary for the oriented cell division and convergent extension that
Autor:
Jing Yang, Michael J. Young, Sunita Saigal, Henry Klassen, Stephen Redenti, William L. Neeley, Santiago B. Rompani, Robert Langer
Publikováno v:
Biomaterials. 30:3405-3414
Retinal degenerations cause permanent visual loss and affect millions world-wide. Presently, a novel treatment highlights the potential of using biodegradable polymer scaffolds to induce differentiation and deliver retinal progenitor cells for cell r
Publikováno v:
Proceedings of the National Academy of Sciences. 105:192-197
Retinal progenitor cells have been shown to be multipotent throughout development. Similarly, many other structures of the developing central nervous system have been found to contain multipotent progenitor cells. Previous lineage studies did not add
Autor:
Daria L. Bancescu, Haiyan Tang, Weimin Zhong, Yan Zhou, Pétur Henry Petersen, Kaiyong Zou, Sinead B. Stewart, Santiago B. Rompani, Joshua B. Atkins
Publikováno v:
Cell. 129(1):163-178
SummaryMammalian neural progenitor cells divide asymmetrically to self-renew and produce a neuron by segregating cytosolic Numb proteins primarily to one daughter cell. Numb signaling specifies progenitor over neuronal fates but, paradoxically, also