Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Santiago Alonso-Gil"'
Autor:
Alexander Stadler, Laryssa V. De Liz, Heloisa B. Gabriel, Santiago Alonso-Gil, Robbie Crickley, Katharina Korbula, Bojan Žagrović, Sue Vaughan, Jack D. Sunter, Gang Dong
Publikováno v:
Open Biology, Vol 14, Iss 9 (2024)
Cilia are antenna-like organelles protruding from the surface of many cell types in the human body. Defects in ciliary structure or function often lead to diseases that are collectively called ciliopathies. Cilia and flagella-associated protein 410 (
Externí odkaz:
https://doaj.org/article/4320de4e24064698b08e96709b1fe3c6
Autor:
Sukanya Luang, Xavier Fernández-Luengo, Alba Nin-Hill, Victor A. Streltsov, Julian G. Schwerdt, Santiago Alonso-Gil, James R. Ketudat Cairns, Stéphanie Pradeau, Sébastien Fort, Jean-Didier Maréchal, Laura Masgrau, Carme Rovira, Maria Hrmova
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Barley β-d-glucan glucohydrolase is a glycoside hydrolase family 3 (GH3) enzyme critical for growth and development. Here the authors carryout mutagenesis, structural analyses and multi-scale molecular dynamics to examine the binding and conformatio
Externí odkaz:
https://doaj.org/article/4f9e72f63f2e475ebb7a7c53d7164632
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
By means of QM(DFT)/MM metadynamics we have unraveled the hydrolytic reaction mechanism of Neisseria polysaccharea amylosucrase (NpAS), a member of GH13 family. Our results provide an atomistic picture of the active site reorganization along the cata
Externí odkaz:
https://doaj.org/article/2055550458294f07bd757653d4a84cf8
Publikováno v:
Nanomaterials, Vol 9, Iss 10, p 1415 (2019)
This work presents experimental and computational studies on ZnO formation after decomposition of a sol-gel precursor containing ethanolamine and Zn(II) acetate. The structural modifications suffered during decomposition of the monomeric and dimeric
Externí odkaz:
https://doaj.org/article/34c5c22e6ed5467386983edf62887242
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Covalent modifications of standard DNA/RNA nucleobases affect epigenetic regulation of gene expression by modulating interactions between nucleic acids and protein readers. We derive here the absolute binding free energies and analyze the bi
Externí odkaz:
https://doaj.org/article/975e9e4bea79405f91e06d79495cd210
Publikováno v:
Biochimie. 195:90-99
Glycoside hydrolase family 31 (GH31) is a diversified family of anomer-retaining α-glycoside hydrolases, such as α-glucosidase and α-xylosidase, among others. Recently, GH31 α-N-acetylgalactosaminidases (Nag31s) have been identified to hydrolyze
Autor:
Alexander Stadler, Heloisa B. Gabriel, Santiago Alonso-Gil, Xuan Deng, Robbie Crickley, Katharina Korbula, Barbora Mikolaskova, Kaiyao Huang, Bojan Zagrovic, Sue Vaughan, Jack D. Sunter, Gang Dong
Cilia and flagella are antenna-like organelles protruding from the surface of most cells in the human body. Defects in ciliary structure or function often lead to diseases that are collectively called ciliopathies. Cilia and flagella associated prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c94b669fc26e44c79059efc20577650
https://doi.org/10.1101/2022.09.21.508879
https://doi.org/10.1101/2022.09.21.508879
Publikováno v:
ChemPlusChem. 85:2534-2541
By employing the computational protocol for calculation of reduction potentials of the Fe4 S4 -containing species validated using a representative series of well-defined synthetic complexes, we focused on redox properties of two prototypical radical
The conformational changes in a sugar moiety along the hydrolytic pathway are key to understand the mechanism of glycoside hydrolases (GHs) and to design new inhibitors. The two predominant itineraries for mannosidases go via OS2 B2,5 1S5 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::487a0d47f4689211cfdc869e7cee6204
https://doi.org/10.26434/chemrxiv-2021-tv8v4
https://doi.org/10.26434/chemrxiv-2021-tv8v4
Publikováno v:
ChemPlusChem. 85(11)
By employing the computational protocol for calculation of reduction potentials of the Fe