Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Santiago Agustín Martínez Gache"'
Autor:
Pyotr A. Tyurin-Kuzmin, Natalie M. Mishina, Alexandra D. Demidovich, Khadija Wahni, Arina G. Shokhina, Sophie Vriz, Yulia D. Maslova, Brandán Pedre, Dmitry S. Bilan, Ivan Bogeski, Emrah Eroglu, Vsevolod V. Belousov, Olga G. Lyublinskaya, Joris Messens, Daria Ezeriņa, Thomas Michel, Valeriy V. Pak, Yulia G. Ermakova, David Young, Santiago Agustín Martínez Gache, Marion Thauvin
Publikováno v:
Cell Metab
Hydrogen peroxide (H(2)O(2)) is a key redox intermediate generated within cells. Existing probes for H(2)O(2) have not solved the problem of detection of the ultra-low concentrations of the oxidant: these reporters are either not sensitive enough, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5906a2ccf23faa8335b190614d272369
https://biblio.vub.ac.be/vubir/ultrasensitive-genetically-encoded-indicator-for-hydrogen-peroxide-identifies-roles-for-the-oxidant-in-cell-migration-and-mitochondrial-function(fbf05804-e4f2-4036-9ac0-cf42874a2779).html
https://biblio.vub.ac.be/vubir/ultrasensitive-genetically-encoded-indicator-for-hydrogen-peroxide-identifies-roles-for-the-oxidant-in-cell-migration-and-mitochondrial-function(fbf05804-e4f2-4036-9ac0-cf42874a2779).html
Autor:
Didier Vertommen, Santiago Agustín Martínez Gache, Nandita Bodra, Caiping Tian, Bo Wei, Khadija Wahni, Joris Messens, Frank Van Breusegem, Kris Gevaert, Kate S. Carroll, Jingjing Huang, Keke Liu, Renan B. Ferreira, Jing Yang, Patrick Willems, Marc Van Montagu
Hydrogen peroxide (H 2 O 2 ) is an important messenger molecule for diverse cellular processes. H 2 O 2 oxidizes proteinaceous cysteinyl thiols to sulfenic acid, also known as S-sulfenylation, thereby affecting the protein conformation and functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c16a1b25e9c9b7241692bea3d10e2f
https://hdl.handle.net/20.500.14017/822242ef-e82f-4567-a4cb-7aa898cd861e
https://hdl.handle.net/20.500.14017/822242ef-e82f-4567-a4cb-7aa898cd861e
Autor:
Jingjing, Huang, Patrick, Willems, Bo, Wei, Caiping, Tian, Renan B, Ferreira, Nandita, Bodra, Santiago Agustín, Martínez Gache, Khadija, Wahni, Keke, Liu, Didier, Vertommen, Kris, Gevaert, Kate S, Carroll, Marc, Van Montagu, Jing, Yang, Frank, Van Breusegem, Joris, Messens
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(42)
Hydrogen peroxide (H(2)O(2)) is an important messenger molecule for diverse cellular processes. H(2)O(2) oxidizes proteinaceous cysteinyl thiols to sulfenic acid, also known as S-sulfenylation, thereby affecting the protein conformation and functiona
Autor:
Santiago Agustín Martínez Gache, Tamara Copetti, Quentin Spillier, Raphaël Frédérick, Zohra Benyahia, Julien R. C. Prevost, Chiara Brustenga, Maxime Liberelle, Joris Messens, Pierre Sonveaux, Arina Kozlova, Léopold Thabault, Lucie Brisson
Publikováno v:
Europe PubMed Central
Journal of medicinal chemistry, Vol. 63, no.9, p. 4628-4643 (2020)
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (9), pp.4628-4643. ⟨10.1021/acs.jmedchem.9b01955⟩
Journal of medicinal chemistry, Vol. 63, no.9, p. 4628-4643 (2020)
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (9), pp.4628-4643. ⟨10.1021/acs.jmedchem.9b01955⟩
Lactate dehydrogenases (LDHs) are tetrameric enzymes of major significance in cancer metabolism as well as promising targets for cancer therapy. However, their wide and polar catalytic sites make them a challenging target for orthosteric inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9ed9c386778b15fbd0d252a75ed1e5
http://europepmc.org/abstract/med/32250117
http://europepmc.org/abstract/med/32250117