Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Santiago, Rodríguez de Córdoba"'
Autor:
Alex González-Alsina, Héctor Martín-Merinero, Margalida Mateu-Borrás, María Verd, Antonio Doménech-Sánchez, Joanna B. Goldberg, Santiago Rodríguez de Córdoba, Sebastián Albertí
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Pseudomonas aeruginosa is a leading cause of nosocomial bloodstream infections. The outcome of these infections depends on the virulence of the microorganism as well as host-related conditions and factors. The complement system plays a crucial role i
Externí odkaz:
https://doaj.org/article/2e235488fce644b8828bca623031de07
Autor:
Alex González-Alsina, Héctor Martín-Merinero, Margalida Mateu-Borrás, María Verd, Antonio Doménech-Sánchez, Joanna B. Goldberg, Santiago Rodríguez de Córdoba, Sebastián Albertí
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Pseudomonas aeruginosa is an important human opportunistic pathogen responsible for a wide range of infections. The complement system is the main early host defense mechanism to control these infections. P. aeruginosa counteracts complement attack by
Externí odkaz:
https://doaj.org/article/f93edac34b274a6e883adb3b4048a991
Autor:
Inmaculada Serrano, Ana Luque, Alexandra Ruiz-Cerulla, Sergio Navas, Anna M. Blom, Santiago Rodríguez de Córdoba, Francisco J. Fernández, M. Cristina Vega, Francisco Rodríguez-Moranta, Jordi Guardiola, Josep M. Aran
Publikováno v:
Pharmacological Research, Vol 197, Iss , Pp 106948- (2023)
The most recent and promising therapeutic strategies for inflammatory bowel disease (IBD) have engaged biologics targeting single effector components involved in major steps of the immune-inflammatory processes, such as tumor necrosis factor, interle
Externí odkaz:
https://doaj.org/article/f67ccb0a5ede42759354bfb33673e0c7
Autor:
Sergio Navas-Yuste, Karla de la Paz, Javier Querol-García, Sara Gómez-Quevedo, Santiago Rodríguez de Córdoba, Francisco J. Fernández, M. Cristina Vega
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Leptospirosis is a neglected worldwide zoonosis involving farm animals and domestic pets caused by the Gram-negative spirochete Leptospira interrogans. This bacterium deploys a variety of immune evasive mechanisms, some of them targeted at the comple
Externí odkaz:
https://doaj.org/article/a34026e7ce4948ab9f46ba962be95cf7
Autor:
Francisco J. Fernández, Jorge Santos-López, Rubén Martínez-Barricarte, Javier Querol-García, Héctor Martín-Merinero, Sergio Navas-Yuste, Martin Savko, William E. Shepard, Santiago Rodríguez de Córdoba, M. Cristina Vega
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Complement activation on foreign cell surfaces leads to the generation of complement opsonins, which activate complement receptor type 3 (CR3) and pathogen clearance by macrophages. Here, the authors reveal structural basis of the interaction between
Externí odkaz:
https://doaj.org/article/78117c6d84b049e588f1750afdba4664
Autor:
Inmaculada Serrano, Ana Luque, Francesca Mitjavila, Anna M. Blom, Santiago Rodríguez de Córdoba, M. Cristina Vega, Joan Torras, Josep M. Aran
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
C4b-binding protein (C4BP) is a well-known regulator of the complement system that holds additional and important activities unrelated to complement inhibition. Recently, we have described a novel immunomodulatory activity in the minor C4BP(β-) isof
Externí odkaz:
https://doaj.org/article/878af3cfcdbd464089ba8c270f8523d8
Autor:
Margarita López-Trascasa, Ángel Alonso-Melgar, Marta Melgosa-Hijosa, Laura Espinosa-Román, María Dolores Lledín-Barbancho, Eugenia García-Fernández, Santiago Rodríguez de Córdoba, Pilar Sánchez-Corral
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Pathogenic gain-of-function variants in complement Factor B were identified as causative of atypical Hemolytic Uremic syndrome (aHUS) in 2007. These mutations generate a reduction on the plasma levels of complement C3. A four-month-old boy was diagno
Externí odkaz:
https://doaj.org/article/0e9d4d23ef784865ac83e627c2a5d986
Autor:
Javier Lumbreras, Marta Subias, Natalia Espinosa, Juana María Ferrer, Emilia Arjona, Santiago Rodríguez de Córdoba
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Thrombotic microangiopathy (TMA) has different etiological causes, and not all of them are well understood. In atypical hemolytic uremic syndrome (aHUS), the TMA is caused by the complement dysregulation associated with pathogenic mutations in comple
Externí odkaz:
https://doaj.org/article/27492a126dd9411c98f483db48b352d4
Autor:
Richard B. Pouw, Irene Gómez Delgado, Alberto López Lera, Santiago Rodríguez de Córdoba, Diana Wouters, Taco W. Kuijpers, Pilar Sánchez-Corral
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/ff78a7793bee449384e22493cbb00574
Autor:
Neeltina M. Jager, Judith E. van Zanden, Marta Subías, Henri G. D. Leuvenink, Mohamed R. Daha, Santiago Rodríguez de Córdoba, Felix Poppelaars, Marc A. Seelen
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Introduction: The majority of kidneys used for transplantation are retrieved from brain-dead organ donors. In brain death, the irreversible loss of brain functions results in hemodynamic instability, hormonal changes and immunological activation. Rec
Externí odkaz:
https://doaj.org/article/827d04cf8aa44199a39266eb9193b63f