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Class switch recombination in the absence of the IgH 3’ regulatory region1

Autor: Kim, Ahrom, Han, Li, Santiago, Gabriel E., Verdun, Ramiro E., Yu, Kefei

The ∼28-kb 3' regulatory region (3'RR), which is located at the most distal 3' region of the Ig H chain locus, has multiple regulatory functions that control IgH expression, class-switch recombination (CSR), and somatic hypermutation. In this artic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::edc7193432fb0a3fa06636cb334f072f
https://europepmc.org/articles/PMC5026946/

Class-Switch Recombination in the Absence of the IgH 3' Regulatory Region.

Autor: Kim A; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824;, Han L; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824;, Santiago GE; Department of Medicine, Division of Hematology-Oncology, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL 33136; and., Verdun RE; Department of Medicine, Division of Hematology-Oncology, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL 33136; and Geriatric Research, Education, and Clinical Center, Miami Veterans Affairs Healthcare System, Miami, FL 33125., Yu K; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824; yuke@msu.edu.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2016 Oct 01; Vol. 197 (7), pp. 2930-5. Date of Electronic Publication: 2016 Aug 24.