Induction of apoptosis in human breast cancer cell line MCF-7 by phytochemicals from Gmelina asiatica

Autor: Merlin, NJ, Parthasarathy, V, Santhoshkumar, TR

Publikováno v: African Journal of Biotechnology; Vol 9, No 28 (2010); 4451-4456

Currently, breast cancer is the leading cause of cancer-related death in women. Therefore, there is an urgent need to develop alternative therapeutic measures against this deadly disease. Many componentsfrom dietary or medicinal plants have been iden

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https://www.ajol.info/index.php/ajb/article/view/82703

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Telomerase inhibitors induce mitochondrial oxidation and DNA damage-dependent cell death rescued by Bcl-2/Bcl-xL.

Autor: Jayaprasad AG; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud, Thiruvananthapuram 695014, Kerala, India; PhD Program, Manipal Academy of Higher Education (MAHE), Madhav Nagar, Manipal, Karnataka 576104, India., Chandrasekharan A; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud, Thiruvananthapuram 695014, Kerala, India., Arun Jyothi SP; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud, Thiruvananthapuram 695014, Kerala, India., John Sam SM; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud, Thiruvananthapuram 695014, Kerala, India., Santhoshkumar TR; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud, Thiruvananthapuram 695014, Kerala, India. Electronic address: trsanthosh@rgcb.res.in., Pillai MR; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud, Thiruvananthapuram 695014, Kerala, India. Electronic address: mrpillai@gmail.com.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2024 Apr; Vol. 264 (Pt 1), pp. 130151. Date of Electronic Publication: 2024 Feb 24.

A high-throughput screening system for SARS-CoV-2 entry inhibition, syncytia formation and cell toxicity.

Autor: Jancy SV; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India., Lupitha SS; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India., Chandrasekharan A; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India., Varadarajan SN; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India., Nelson-Sathi S; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India., Prasad R; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India., Jones S; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India., Easwaran S; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India., Darvin P; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India., Sivasailam A; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India., Santhoshkumar TR; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India. trsanthosh@rgcb.res.in.

Publikováno v: Biological procedures online [Biol Proced Online] 2023 Jul 26; Vol. 25 (1), pp. 22. Date of Electronic Publication: 2023 Jul 26.

Endosomal-associated RFFL facilitates mitochondrial clearance by enhancing PRKN/parkin recruitment to mitochondria.

Autor: Ravindran R; School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Kerala, India., Velikkakath AKG; School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Kerala, India.; Central Research Laboratory, K.S. Hegde Medical Academy, Nitte (Deemed to Be University), Karnataka, India., Narendradev ND; School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Kerala, India., Chandrasekharan A; Cancer Research Program-1, Rajiv Gandhi Centre for Biotechnology, Kerala, India., Santhoshkumar TR; Cancer Research Program-1, Rajiv Gandhi Centre for Biotechnology, Kerala, India., Srinivasula SM; School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Kerala, India.

Publikováno v: Autophagy [Autophagy] 2022 Dec; Vol. 18 (12), pp. 2851-2864. Date of Electronic Publication: 2022 Apr 03.