Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Santhosh Kumar Nagarajan"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1711-1727 (2023)
Claudin proteins constitute the backbone of tight junctions (TJs) regulating paracellular permeability for solutes and water. The molecular mechanism of claudin polymerization and paracellular channel formation is unclear. However, a joined double-ro
Externí odkaz:
https://doaj.org/article/7a1208e0100e4ed281538979ae7afda7
Autor:
Santhosh Kumar Nagarajan, Sathya Babu, Seema A. Kulkarni, Aanand Vadivelu, Panneer Devaraju, Honglae Sohn, Thirumurthy Madhavan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Somatostatin receptor 2 (SSTR2) is a G-protein coupled receptor (GPCR) that controls numerous cellular processes including cell-to-cell signaling. In this study, we report how the lipid and ligand molecules influence the conformational dynam
Externí odkaz:
https://doaj.org/article/d7b23b4ad2684bf38c546fb52cba4cdb
Autor:
Sathya Babu, Santhosh Kumar Nagarajan, Sruthy Sathish, Vir Singh Negi, Honglae Sohn, Thirumurthy Madhavan
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
JAK1 plays a significant role in the intracellular signaling by interacting with cytokine receptors in different types of cells and is linked to the pathogenesis of various cancers and in the pathology of the immune system. In this study, ligand-base
Externí odkaz:
https://doaj.org/article/acebbe9c4fac4327bbe577d5d511b605
Publikováno v:
ACS Omega, Vol 5, Iss 33, Pp 21145-21161 (2020)
Externí odkaz:
https://doaj.org/article/9e7d0fdd6fe449b6a13787d17fe8518a
Autor:
Seema A. Kulkarni, Santhosh Kumar Nagarajan, Emmanuel Rotimi Sadiku, Thirumurthy Madhavan, Periyar Selvam Sellamuthu
Publikováno v:
South African Journal of Botany. 144:166-174
This study aimed to examine the antifungal activity of wild bergamot (Monarda fistulosa) essential oil on Colletotrichum musae and Lasiodiplodia theobromae, the causative organisms of anthracnose and crown-rot diseases of banana fruits, respectively.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5eb48cb671be0b9033c36c034ebe751
https://doi.org/10.1016/j.sajb.2021.08.019
https://doi.org/10.1016/j.sajb.2021.08.019
Autor:
Arumugam R. Jayakumar, Mohamed Saiyad Musthafa, Santhosh Kumar Nagarajan, Kantha D. Arunachalam, Pamela Sinha, Thirumurthy Madhavan
Publikováno v:
International Journal of Radiation Biology. 98:212-229
Purpose Freshwater fish Pangasius sutchi was used in this study as a vertebrate model. We evaluated the induction of certain antioxidant enzymes in various vital organs. The radioprotective efficacy of Gymnema sylvestre leaves extract (GS) [25 mg/kg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6433352a45890d267a4a5020df73c6f
https://doi.org/10.1080/09553002.2022.1998701
https://doi.org/10.1080/09553002.2022.1998701
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 90:704-719
In the past two decades, the structural biology studies on G-protein coupled receptors (GPCRs) are on the rise. Understanding the relation between the structure and function of GPCRs is important as they play a huge role in various signaling mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dea9a5ebf9e45be4ab5da8994529f96
https://doi.org/10.1002/prot.26267
https://doi.org/10.1002/prot.26267
Publikováno v:
ACS Omega
ACS Omega, Vol 5, Iss 33, Pp 21145-21161 (2020)
ACS Omega, Vol 5, Iss 33, Pp 21145-21161 (2020)
Somatostatin receptor 1 (SSTR1), a subtype of somatostatin receptors, is involved in various signaling mechanisms in different parts of the human body. Like most of the G-protein-coupled receptors (GPCRs), the available information on the structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07195e097b4d6825ca4459b9c579df61
http://europepmc.org/articles/PMC7450625
http://europepmc.org/articles/PMC7450625
Autor:
Pamela, Sinha, Kantha Devi, Arunachalam, Santhosh Kumar, Nagarajan, Thirumurthy, Madhavan, Arumugam, R Jayakumar, Mohamed, Saiyad Musthafa
Publikováno v:
International journal of radiation biology. 98(2)
Freshwater fishThis study was done via stress marker enzymes, cell cycle analysis (CCA) and DNA damage assay prediction with molecular docking, which are reported here for the first time. The results indicate an elevated LPO level and decreased level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::214f8e0715f58dae8d01dd71b8a3ec3f
https://pubmed.ncbi.nlm.nih.gov/34705596
https://pubmed.ncbi.nlm.nih.gov/34705596
Publikováno v:
ChemistrySelect. 4:3990-4002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45707561ab20cc0762fc220aa11ad394
https://doi.org/10.1002/slct.201803387
https://doi.org/10.1002/slct.201803387