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Controversy and Consensus on the Management of Elevated Sperm DNA Fragmentation in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations.

Autor: Farkouh A; Global Andrology Forum, American Center for Reproductive Medicine, Moreland Hills, OH, USA., Agarwal A; Global Andrology Forum, American Center for Reproductive Medicine, Moreland Hills, OH, USA.; Cleveland Clinic Foundation, Cleveland, OH, USA. agarwaa32099@outlook.com., Hamoda TAA; Department of Urology, King Abdulaziz University, Jeddah, Saudi Arabia.; Department of Urology, Faculty of Medicine, Minia University, Minia, Egypt., Kavoussi P; Department of Reproductive Urology, Austin Fertility & Reproductive Medicine/Westlake IVF, Austin, TX, USA., Saleh R; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Sohag University, Sohag, Egypt.; Ajyal IVF Center, Ajyal Hospital, Sohag, Egypt., Zini A; Department of Surgery, McGill University, Montreal, QC, Canada., Arafa M; Department of Urology, Hamad Medical Corporation, Doha, Qatar.; Department of Andrology, Sexology & STIs, Cairo University, Cairo, Egypt.; Department of Urology, Weill Cornell Medical-Qatar, Doha, Qatar., Harraz AM; Urology Department, Urology and Nephrology Center, Mansoura University, Mansura, Egypt.; Department of Surgery, Urology Unit, Farwaniya Hospital, Farwaniya, Kuwait.; Department of Urology, Sabah Al Ahmad Urology Center, Kuwait City, Kuwait., Gul M; Department of Urology, Selçuk University School of Medicine, Konya, Turkey., Karthikeyan VS; Andrology Unit, Department of Urology, Apollo Hospitals, Chennai, India., Durairajanayagam D; Department of Physiology, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Selangor, Malaysia., Rambhatla A; Department of Urology, Henry Ford Health System, Vattikuti Urology Institute, Detroit, MI, USA., Boitrelle F; Reproductive Biology, Fertility Preservation, Andrology, CECOS, Poissy Hospital, Poissy, France.; Department of Biology, Reproduction, Epigenetics, Environment and Development, Paris Saclay University, UVSQ, INRAE, BREED, Jouy-en-Josas, France., Chung E; Department of Urology, Princess Alexandra Hospital, University of Queensland, Brisbane, QLD, Australia., Birowo P; Department of Urology, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia., Toprak T; Department of Urology, Fatih Sultan Mehmet Training and Research Hospital, University of Health Sciences, Istanbul, Turkey., Ghayda RA; Urology Institute, University Hospitals, Case Western Reserve University, Cleveland, OH, USA., Cannarella R; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.; Department of Urology, Glickman Urological & Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH, USA., Phuoc NHV; Department of Andrology, Binh Dan Hospital, Ho Chi Minh City, Vietnam.; Department of Urology and Andrology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam., Dimitriadis F; Department of Urology, Aristotle University, School of Medicine, Thessaloniki, ., Russo GI; Urology Section, University of Catania, Catania, Italy., Sokolakis I; Department of Urology, Aristotle University, School of Medicine, Thessaloniki, ., Mostafa T; Department of Andrology, Sexology & STIs, Cairo University, Cairo, Egypt., Makarounis K; Department of Urology and Andrology, Locus Medicus, Athens, Greece., Ziouziou I; Department of Urology, College of Medicine and Pharmacy, Ibn Zohr University, Agadir, Morocco., Kuroda S; Department of Urology, Glickman Urological & Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH, USA., Bendayan M; Reproductive Biology, Fertility Preservation, Andrology, CECOS, Poissy Hospital, Poissy, France., Kaiyal RS; Department of Urology, Glickman Urological & Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH, USA., Japari A; Fertility Clinic, Telogorejo Hospital, Semarang, Indonesia., Simopoulou M; Department of Physiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece., Rocco L; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania Luigi Vanvitelli, Caserta, Italy., Garrido N; IVI Foundation, Instituto de Investigación Sanitaria La Fe (IIS La Fe), Valencia, Spain., Gherabi N; Department of Urology, University of Algiers, Algiers, Algeria., Bocu K; Department of Urology, Silopi State Hospital, Sirnak, Turkey., Kahraman O; Department of Urology, Faculty of Medicine, Baskent University, Ankara, Turkey., Le TV; Department of Andrology, Binh Dan Hospital, Ho Chi Minh City, Vietnam.; Department of Urology and Andrology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam., Wyns C; Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium., Tremellen K; Department of Obstetrics Gynaecology and Reproductive Medicine, Flinders University, South Australia, Australia., Sarikaya S; Department of Urology, Gülhane Research and Training Hospital, University of Health Sciences, Ankara, Turkey., Lewis S; Examen Lab Ltd., Northern Ireland, UK., Evenson DP; SCSA Diagnostics, Brookings, SDUSA, USA., Ko E; Department of Urology, Loma Linda University Health, Loma Linda, CA, USA., Calogero AE; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy., Bahar F; Andrology Section, Siloam Sriwijaya Hospital, Palembang, Indonesia., Martinez M; Section of Urology, Department of Surgery, University of Santo Tomas Hospital, Manila, Philippines., Crafa A; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy., Nguyen Q; Center for Andrology and Sexual Medicine, Viet Duc University Hospital, Hanoi, Vietnam.; Department of Urology, Andrology and Sexual Medicine, University of Medicine and Pharmacy, Vietnam National University, Hanoi, Vietnam., Ambar RF; Department of Urology, Centro Universitario em Saude do ABC, Santo André, Brazil.; Andrology Group at Ideia Fertil Institute of Human Reproduction, Santo André, Brazil., Colpi G; Andrology and IVF Center, Next Fertility Procrea, Lugano, Switzerland., Bakircioglu ME; SENSART Clinic, Urology, Fulya, Istanbul, Turkey., Henkel R; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; Department of Medical Bioscience, University of the Western Cape, Bellville, South Africa., Kandil H; Fakih IVF Fertility Center, Abu Dhabi, UAE., Serefoglu EC; Department of Urology, Biruni University School of Medicine, Istanbul, Turkey., Alarbid A; Department of Surgery, Urology Unit, Farwaniya Hospital, Farwaniya, Kuwait., Tsujimura A; Department of Urology, Juntendo University Urayasu Hospital, Chiba, Japan., Kheradmand A; Urology Department, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Anagnostopoulou C; Unit of Reproductive Medicine-EmbryoART, Leto Maternity Hospital, Athens, Greece., Marino A; ANDROS Day Surgery Clinic, Reproductive Medicine Unit, Palermo, Italy., Adamyan A; IVF Department, Astghik Medical Center, Yerevan, Armenia., Zilaitiene B; Institute of Endocrinology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania., Ozer C; Department of Urology, Faculty of Medicine, Baskent University, Ankara, Turkey., Pescatori E; Andrology and Reproductive Medicine Unit, Gynepro Medical, Bologna, Italy., Vogiatzi P; Andromed Health & Reproduction, Fertility & Reproductive Health Diagnostic Center, Athens, Greece., Busetto GM; Department of Urology and Renal Transplantation, University of Foggia, Policlinico Riuniti, Foggia, Italy., Balercia G; Department of Endocrinology, Polytechnic University of Marche, Ancona, Italy., Elbardisi H; Department of Urology, Hamad Medical Corporation, Doha, Qatar.; Department of Andrology, Sexology & STIs, Cairo University, Cairo, Egypt., Akhavizadegan H; Department of Urology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran., Sajadi H; Department of Andrology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Teheran, Iran., Taniguchi H; Department of Urology and Andrology, Kansai Medical University, Hirakata, Osaka, Japan., Park HJ; Department of Urology, Pusan National University School of Medicine, Busan, Korea.; Medical Research Institute of Pusan National University Hospital, Busan, Korea., Maldonado Rosas I; IVF Laboratory, CITMER Reproductive Medicine, Mexico City, Mexico., Al-Marhoon M; Division of Urology, Department of Surgery, Sultan Qaboos University, Muscat, Sultanate of Oman., Sadighi Gilani MA; Department of Andrology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Teheran, Iran., Alhathal N; King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia., Pinggera GM; Department of Urology, Innsbruck Medical University, Innsbruck, Austria., Kothari P; Department of Urology, Topiwala National Medical College, B.Y.L Nair Ch Hospital, Mumbai, India., Mogharabian N; Sexual Health and Fertility Research Center, Shahroud University of Medical Sciences, Shahroud, Iran., Micic S; Department of Andrology, Uromedica Polyclinic, Belgrade, Serbia., Homa S; Department of Biosciences, University of Kent, Canterbury, UK., Darbandi S; Fetal Health Research Center, Hope Generation Foundation, Tehran, Iran.; Gene Therapy and Regenerative Medicine Research Center, Hope Generation Foundation, Tehran, Iran., Long TQT; Department of Obstetrics and Gynecology, Hanoi Obstetrics and Gynecology Hospital, Hanoi, Vietnam., Zohdy W; Department of Andrology, Sexology & STIs, Cairo University, Cairo, Egypt., Atmoko W; Department of Urology, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia., Sabbaghian M; Department of Andrology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Teheran, Iran., Ibrahim W; Department of Obstetrics Gynaecology and Reproductive Medicine, Fertility Care Center in Cairo, Cairo, Egypt., Smith RP; Department of Urology, University of Virginia School of Medicine, Virginia, USA., Ho CCK; Department of Surgery, School of Medicine, Taylor's University, Subang Jaya, Selangor, Malaysia., de la Rosette J; Department of Urology, Istanbul Medipol University, Istanbul, Turkey., El-Sakka AI; Department of Urology, Suez Canal University, Ismailia, Egypt., Preto M; Department of Urology, University of Turin, Turin, Italy., Zenoaga-Barbăroșie C; Department of Genetics, Faculty of Biology, University of Bucharest, Bucharest, Romania., Abumelha SM; Division of Urology, Department of Surgery, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Baser A; Department of Urology, Bandirma Onyedi Eylül University, Balikesir, Turkey., Aydos K; Department of Urology, Ankara University, Ankara, Turkey., Ramirez-Dominguez L; IVF Laboratory, CITMER Reproductive Medicine, Mexico City, Mexico., Kumar V; Department of Microbiology, Kurukshetra University, Kurukshetra, India., Ong TA; Department of Surgery, University of Malaya, Kuala Lumpur, Malaysia., Mierzwa TC; Androlab, Fertility Clinic, Curitiba, PR, Brazil., Adriansjah R; Department of Urology, Faculty of Medicine of Padjadjaran University, Hasan Sadikin General Hospital, Bandung, Indonesia., Banihani SA; Department of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid, Jordan., Bowa K; Department of Urology, University of Lusaka, Lusaka, Zambia., Fukuhara S; Department of Urology, Graduate School of Medicine, Osaka University, Osaka, Japan., Rodriguez Peña M; Instituto de Ginecologia y Fertilidad (IFER), Buenos Aire, Argentina., Moussa M; Department of Urology, Lebanese University, Beirut, Lebanon.; Department of Urology, Al Zahraa Hospital, UMC, Lebanon., Ari UÇ; Department of Reproduction, Kafkas University, Kars, Turkey., Cho CL; S. H. Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong., Tadros NN; Division of Urology, Southern Illinois University, Springfield, IL, USA., Ugur MR; IVF Michigan, Bloomfield Hills, MI, USA., Amar E; American Hospital of Paris, Paris, France., Falcone M; Department of Urology, Molinette Hospital, A.O.U. Città della Salute e della Scienza, University of Turin, Torino, Italy., Santer FR; Department of Urology, Innsbruck Medical University, Innsbruck, Austria., Kalkanli A; Department of Urology, Taksim Education and Research Hospital, Istanbul, Turkey., Karna KK; Department of Molecular Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA., Khalafalla K; Department of Urology, Hamad Medical Corporation, Doha, Qatar.; Urology Department, University of Texas McGovern Medical School, Houston, TX, USA.; Urology Department, MD Anderson Cancer Center, Houston, TX, USA., Vishwakarma RB; Division of Andrology, Department of Urology, Lilavati Hospital and Research Centre, Mumbai, India., Finocchi F; Department of Endocrinology, Polytechnic University of Marche, Ancona, Italy., Giulioni C; Department of Urology, Polytechnic University of Marche Region, Ancona, Italy., Ceyhan E; Department of Urology, Faculty of Medicine, Baskent University, Ankara, Turkey., Çeker G; Department of Urology, Başakşehir Çam and Sakura City Hospital, Istanbul, Turkey., Yazbeck C; Obstetrics Gynecology and Reproductive Medicine, Reprogynes Medical Institute, Paris, France., Rajmil O; Department of Andrology, Fundacio Puigvert, Barcelona, Spain., Yilmaz M; Asklepios Clinic Triberg, Urology, Freiburg, Germany., Altay B; Department of Urology, Ege University, Izmir, Turkey., Barrett TL; Perth Urology Clinic, Perth, WA, Australia., Ngoo KS; Hospital Angkatan Tentera Tuanku Mizan, Kuala Lumpur, Malaysia., Roychoudhury S; Department of Life Science and Bioinformatics, Assam University, Silchar, India., Salvio G; Department of Endocrinology, Polytechnic University of Marche, Ancona, Italy., Lin H; Department of Urology, Peking University Third Hospital, Beijing, China., Kadioglu A; Section of Andrology, Department of Urology, Istanbul University, Istanbul, Turkey., Timpano M; Department of Urology, Molinette Hospital, A.O.U. Città della Salute e della Scienza, University of Turin, Torino, Italy., Avidor-Reiss T; Department of Biological Sciences, University of Toledo, Toledo, OH, USA.; Department of Urology and Transplantation, University of Toledo, Toledo, OH, USA., Hakim L; Department of Urology, Universitas Airlangga, Rumah Sakit Universitas Airlangga Teaching Hospital, Surabaya, Indonesia., Sindhwani P; Department of Urology, Universitas Airlangga, Rumah Sakit Universitas Airlangga Teaching Hospital, Surabaya, Indonesia., Franco G; Department of Urology, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy., Singh R; Division of Endocrinology, Central Drug Research Institute, Lucknow, India., Giacone F; Centro HERA, Unità di Medicina della Riproduzione, Sant'Agata Li Battiati, Catania, Italy., Ruzaev M; Private Clinic, Moscow, Russia., Kosgi R; Department of Urology, Andrology and Renal Transplant, AIG Hospitals, Hyderabad, India., Sofikitis N; Department of Urology, Ioannina University School of Medicine, Ioannina, Greece., Palani A; Research Centre, University of Garmian, Kalar, Iraq., Calik G; Department of Urology, Istanbul Medipol University, Istanbul, Turkey., Kulaksız D; Department of Obstetrics and Gynecology, University of Health Sciences Kanuni Training and Research Hospital, Trabzon, Turkey., Jezek D; Department for Transfusion Medicine and Transplantation Biology, Reproductive Tissue Bank, University Hospital Zagreb, Zagreb, Croatia., Al Hashmi M; Department of Urology, Burjeel Hospital, Abu Dhabi, UAE.; Department of Urology, College of Medicine and Health Science, Khalifa University, Abu Dhabi, UAE., Drakopoulos P; Centre for Reproductive Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.; IVF Athens, Athens, Greece., Omran H; Al Aljenan Medical Center, Pulse Health Training Center, Manama, Kingdom of Bahrain., Leonardi S; Central Laboratory, Hospital Público Materno Infantil de Salta, Salta, Argentina., Celik-Ozenci C; Department of Histology and Embryology, Faculty of Medicine, Koç University, Istanbul, Turkey., Güngör ND; Department of Obstetrics and Gynecology, Reproductive Endocrinology and IVF Unit, School of Medicine, Bahcesehir University, Istanbul, Turkey., Ramsay J; Department of Andrology, Hammersmith Hospital, London, UK., Amano T; Department of Urology, Nagano Red Cross Hospital, Nagano, Japan., Sogutdelen E; Department of Urology, Bolu Abant Izzet Baysal University, Bolu, Turkey., Duarsa GWK; Department of Urology, Udayana University, Denpasar, Indonesia., Chiba K; Department of Urology, Kobe University Graduate School of Medicine, Kobe, Japan., Jindal S; Department of Andrology and Reproductive Medicine, Jindal Hospital, Meerut, India., Savira M; Department of Urology, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia., Boeri L; Department of Urology, IRCCS Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy., Borges E; Fertility Assisted Fertilization Center, São Paulo, Brazil., Gupte D; Department of Urology, Bombay Hospital and Medical Research Center, Mumbai, India., Gokalp F; Department of Urology, Hatay Mustafa Kemal University, Antakya, Turkey., Hebrard GH; IVF Laboratory, CITMER Reproductive Medicine, Mexico City, Mexico., Minhas S; Division of Surgery, Department of Surgery and Cancer, Imperial College, London, UK., Shah R; Division of Andrology, Department of Urology, Lilavati Hospital and Research Centre, Mumbai, India.

Publikováno v: The world journal of men's health [World J Mens Health] 2023 Oct; Vol. 41 (4), pp. 809-847. Date of Electronic Publication: 2023 Apr 20.

MYC-Mediated Ribosomal Gene Expression Sensitizes Enzalutamide-resistant Prostate Cancer Cells to EP300/CREBBP Inhibitors.

Autor: Furlan T; Department of Urology, Medical University of Innsbruck, Innsbruck, Austria., Kirchmair A; Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria., Sampson N; Department of Urology, Medical University of Innsbruck, Innsbruck, Austria., Puhr M; Department of Urology, Medical University of Innsbruck, Innsbruck, Austria., Gruber M; Department of Urology, Medical University of Innsbruck, Innsbruck, Austria., Trajanoski Z; Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria., Santer FR; Department of Urology, Medical University of Innsbruck, Innsbruck, Austria., Parson W; Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria; Forensic Science Program, The Pennsylvania State University, University Park, Pennsylvania., Handle F; Department of Urology, Medical University of Innsbruck, Innsbruck, Austria., Culig Z; Department of Urology, Medical University of Innsbruck, Innsbruck, Austria. Electronic address: zoran.culig@i-med.ac.at.

Publikováno v: The American journal of pathology [Am J Pathol] 2021 Jun; Vol. 191 (6), pp. 1094-1107. Date of Electronic Publication: 2021 Mar 08.

The STAT3 Inhibitor Galiellalactone Reduces IL6-Mediated AR Activity in Benign and Malignant Prostate Models.

Autor: Handle F; Division of Experimental Urology, Department of Urology, Medical University of Innsbruck, Innsbruck, Austria.; Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Puhr M; Division of Experimental Urology, Department of Urology, Medical University of Innsbruck, Innsbruck, Austria., Schaefer G; Department of Pathology, Medical University of Innsbruck, Innsbruck, Austria., Lorito N; Division of Experimental Urology, Department of Urology, Medical University of Innsbruck, Innsbruck, Austria., Hoefer J; Division of Experimental Urology, Department of Urology, Medical University of Innsbruck, Innsbruck, Austria., Gruber M; Division of Experimental Urology, Department of Urology, Medical University of Innsbruck, Innsbruck, Austria., Guggenberger F; Division of Experimental Urology, Department of Urology, Medical University of Innsbruck, Innsbruck, Austria., Santer FR; Division of Experimental Urology, Department of Urology, Medical University of Innsbruck, Innsbruck, Austria., Marques RB; Department of Urology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., van Weerden WM; Department of Urology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Claessens F; Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Erb HHH; Department of Urology and Pediatric Urology, University Medical Center Mainz, Mainz, Germany., Culig Z; Division of Experimental Urology, Department of Urology, Medical University of Innsbruck, Innsbruck, Austria. zoran.culig@i-med.ac.at.

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2018 Dec; Vol. 17 (12), pp. 2722-2731. Date of Electronic Publication: 2018 Sep 25.

Fractionated Radiation of Primary Prostate Basal Cells Results in Downplay of Interferon Stem Cell and Cell Cycle Checkpoint Signatures.

Autor: Guggenberger F; Department of Urology, Division of Experimental Urology, Medical University of Innsbruck, Innsbruck, Austria., van de Werken HJG; Cancer Computational Biology Center, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., Erb HHH; Department of Urology and Pediatric Urology, University Medical Center Mainz, Mainz, Germany., Cappellano G; Department of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Innsbruck, Innsbruck, Austria., Trattnig K; Department of Urology, Division of Experimental Urology, Medical University of Innsbruck, Innsbruck, Austria., Handle F; Department of Urology, Division of Experimental Urology, Medical University of Innsbruck, Innsbruck, Austria., Peer S; Department of Urology, Division of Experimental Urology, Medical University of Innsbruck, Innsbruck, Austria., Schäfer G; Department of Pathology, Medical University of Innsbruck, Innsbruck, Austria., Jenster G; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., Culig Z; Department of Urology, Division of Experimental Urology, Medical University of Innsbruck, Innsbruck, Austria., Skvortsova I; Department of Radiotherapy and Radiooncology, Medical University of Innsbruck, Innsbruck, Austria., Santer FR; Department of Urology, Division of Experimental Urology, Medical University of Innsbruck, Innsbruck, Austria. Electronic address: frederic.santer@i-med.ac.at.

Publikováno v: European urology [Eur Urol] 2018 Dec; Vol. 74 (6), pp. 847-849. Date of Electronic Publication: 2018 Jun 18.