Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status

Autor: Lyons, P. A., Peters, J. E., Alberici, F., Liley, J., Coulson, R. M. R., Astle, W., Baldini, C., Bonatti, F., Cid, María Cinta, Elding, H., Emmi, G., Epplen, J., Guillevin, L., Jayne, D. R. W., Jiang, T., Gunnarsson, I., Lamprecht, P., Leslie, S., Little, M. A., Martorana, D., Moosig, F., Neumann, T., Ohlsson, S., Quickert, S., Ramirez, G. A., Rewerska, B., Schett, George, Sinico, R. A., Szczeklik, W., Tesar, Vladimir, Vukcevic, D., Akil, M., Barratt, J., Basu, N., Butterworth, A. S., Bruce, I., Clarkson, M., Conlon, N., DasGupta, B., Doulton, T. W. R., Espígol-Frigolé, Georgina, Flossmann, O., Gabrielli, A., Gasior, J., Gregorini, G., Guida, G., Hernández Rodríguez, José, Hruskova, Z., Hudson, A., Knight, A., Lanyon, P., Luqmani, R., Magliano, M., Manfredi, A. A., Marguerie, C., Maritati, F., Marvisi, C., McHugh, N. J., Molloy, E., Motyer, A., Mukhtyar, C., Padyukov, Leonid, Pesci, Alberto, Prieto-Gonzalez, S., Ramentol-Sintas, Marc, Reis, P., Roccatello, D., Rovere-Querini, P., Salvarani, C., Santarsia, F., Solans, Roser, Soranzo, N., Taylor, J., Wessels, J., Zwerina, J., Terrier, B., Watts, R. A., Vaglio, A., Holle, J. U., Wallace, C., Smith, K. G. C., Universitat Autònoma de Barcelona

Publikováno v: Nature Communications
Lyons, P A, Peters, J E, Alberici, F, Liley, J, Coulson, R M R, Astle, W, Baldini, C, Bonatti, F, Cid, M C, Elding, H, Emmi, G, Epplen, J, Guillevin, L, Jayne, D R W, Jiang, T, Gunnarsson, I, Lamprecht, P, Leslie, S, Little, M A, Martorana, D, Moosig, F, Neumann, T, Ohlsson, S, Quickert, S, Ramirez, G A, Rewerska, B, Schett, G, Sinico, R A, Szczeklik, W, Tesar, V, Vukcevic, D, Terrier, B, Watts, R A, Vaglio, A, Holle, J U, Wallace, C & Smith, K G C 2019, ' Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status ', Nature Communications, vol. 10, no. 1 . https://doi.org/10.1038/s41467-019-12515-9
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disease of unknown cause. 30% of patients have anti-neutrophil cytoplasmic antibodies (ANCA) specific for myeloperoxidase (MPO). Here, we describe a genome-wide association s

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http://hdl.handle.net/11568/1063464

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