Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sanskruti Vaidya"'
Autor:
Mariko Nakagomi, Hidenori Arai, Hiroyuki Daida, Masayoshi Shirakawa, Hirotaka Numaguchi, Sanskruti Vaidya, Taro Kakikawa, Yuko Maeda, Amy O. Johnson-Levonas, Tamio Teramoto, Katsunori Ikewaki, Robert O. Blaustein
Publikováno v:
Atherosclerosis. 249:215-223
This multicenter, randomized, double-blind, placebo-controlled study assessed the lipid-modifying efficacy/safety profile of anacetrapib 100 mg added to ongoing statin ± other lipid-modifying therapies (LMT) in Japanese patients with heterozygous fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc1c2ce538da972916b6199a209a160
https://doi.org/10.1016/j.atherosclerosis.2016.03.017
https://doi.org/10.1016/j.atherosclerosis.2016.03.017
Autor:
Eliot A. Brinton, Antonio M. Gotto, Jennifer Moon, Philip J. Barter, Uma Kher, Sukrut Shah, Manash Shankar Chatterjee, Yang Liu, Christopher P. Cannon, Yale B. Mitchel, Xiujiang Susie Li, Sanskruti Vaidya, Hayes M. Dansky
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 19:543-549
Anacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that has previously been shown to reduce low-density lipoprotein cholesterol (LDL-C) and raise high-density lipoprotein cholesterol (HDL-C) in patients with or at high risk of coron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6136bb88d55b26e0d226f8db9e62d6a
https://doi.org/10.1177/1074248414529621
https://doi.org/10.1177/1074248414529621
Autor:
Sanskruti Vaidya, Elizabeth P. Somers, Samuel D. Wright, Patricia A. Detmers, Vinay S. Bansal
Publikováno v:
The Journal of Immunology. 163:6187-6192
15-Deoxy-Δ12,14-PGJ2 (dPGJ2) is a bioactive metabolite of the J2 series that has been identified as a ligand for peroxisome proliferator-activated receptor γ (PPARγ) and has received attention for its potential antiinflammatory effects. Because ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a29103e90a75917a10c294ed99bebaea
https://doi.org/10.4049/jimmunol.163.11.6187
https://doi.org/10.4049/jimmunol.163.11.6187
Autor:
Patricia A. Detmers, Dahua Zhou, Elizabeth Polizzi, Rolf Thieringer, William A. Hanlon, Sanskruti Vaidya, Vinay Bansal
Publikováno v:
The Journal of Immunology. 161:1921-1929
Bacterial LPS elicits both rapid activation of the stress-activated MAP kinase p38 in polymorphonuclear leukocytes (PMN) and rapid adhesion of the PMN to ligands for the leukocyte integrin CD11b/CD18. The functional correlation between these two even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17ef43426c28b18d9c572503519b1b77
https://doi.org/10.4049/jimmunol.161.4.1921
https://doi.org/10.4049/jimmunol.161.4.1921
Autor:
Hayes M. Dansky, Jennifer Moon, Michael H. Davidson, Eliot A. Brinton, Antonio M. Gotto, Sukrut Shah, Philip J. Barter, Uma Kher, Sanskruti Vaidya, Yale B. Mitchel, Xiujiang Susie Li, Christopher P. Cannon
Publikováno v:
The American journal of cardiology. 113(1)
The aim of this study was to assess the effects on lipids and safety during a 12-week reversal period after 18 months of treatment with anacetrapib. The cholesteryl ester transfer protein inhibitor anacetrapib was previously shown to reduce low-densi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009206a77c9888387edfef5158b6911f
https://pubmed.ncbi.nlm.nih.gov/24188894
https://pubmed.ncbi.nlm.nih.gov/24188894
Autor:
V. S. Bansal, Sanskruti Vaidya
Publikováno v:
Archives of Biochemistry and Biophysics. 315:393-399
We have identified and characterized two novel allyl pyrophosphatase activities from rat liver microsomes. One specifically hydrolyzes farnesyl pyrophosphate (FPP) to farnesol and the other converts geranylgeranyl pyrophosphate (GGPP) to geranylgeran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e782cf591b792612f176c2ac83c980b2
https://doi.org/10.1006/abbi.1994.1516
https://doi.org/10.1006/abbi.1994.1516
Autor:
Renee Weikel, Sanskruti Vaidya, Mansi Kanuga, Diane Shevell, Elizabeth P. Somers, Vinay S. Bansal, Patricia A. Detmers
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 304(3)
The leukocyte integrin complement receptor type 3 (CR3, Mac-1, CD11b/CD18) is the predominant beta(2) integrin receptor of polymorphonuclear leukocytes (PMNs). This cell surface receptor plays a central role in innate immunity against pathogens as we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fce268a487e91f12736aaf9a79020ae
https://pubmed.ncbi.nlm.nih.gov/12604677
https://pubmed.ncbi.nlm.nih.gov/12604677
Autor:
Hayes M. Dansky, Uma Kher, Sukrut Shah, Christopher E. Cannon, Philip Barter, Yang Liu, Sanskruti Vaidya, Antonio M. Gotto, Michael H. Davidson, Yale B. Mitchel, Manash Shankar Chatterjee, Xiujiang Susie Li, Jennifer Moon, Eliot Brinton
Publikováno v:
Journal of the American College of Cardiology. 63:A1449
Anacetrapib is a cholesteryl ester transfer protein inhibitor that has previously been shown to be well tolerated, reduce low-density lipoprotein cholesterol (LDL-C) and raise high-density lipoprotein cholesterol (HDL-C) in patients with or at high r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7e2f96a49bb3d2443d9e6abfda2be0
https://doi.org/10.1016/s0735-1097(14)61449-2
https://doi.org/10.1016/s0735-1097(14)61449-2
Publikováno v:
Archives of biochemistry and biophysics. 355(1)
The zaragozic acids are potent inhibitors of squalene synthase. In vivo studies in mice confirmed our earlier observations that inhibition of squalene synthase by zaragozic acid A was accompanied by an increase in the incorporation of label from [ 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2d35fba9c23864df4e0ed729413d73
https://pubmed.ncbi.nlm.nih.gov/9647670
https://pubmed.ncbi.nlm.nih.gov/9647670
Autor:
John D. Karkas, Marc M. Kurtz, Byron H. Arison, Richard G. Bostedor, Sanskruti Vaidya, James D. Bergstrom, Vinay S. Bansal, John I. Germershausen
Publikováno v:
The Journal of biological chemistry. 272(14)
Farnesyl diphosphate, the substrate for squalene synthase, accumulates in the presence of zaragozic acid A, a squalene synthase inhibitor. A possible metabolic fate for farnesyl diphosphate is its conversion to farnesol, then to farnesoic acid, and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc0ddc388ce2ab2569efc0529dc0a7e
https://pubmed.ncbi.nlm.nih.gov/9083051
https://pubmed.ncbi.nlm.nih.gov/9083051