Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Sanni Söderlund"'
Autor:
Marianna Viukari, Helena Leijon, Tiina Vesterinen, Sanni Söderlund, Päivi Hämäläinen, Iina Yliaska, Päivi Rautiainen, Reeta Rintamäki, Minna Soinio, Ilkka Pörsti, Pasi I Nevalainen, Niina Matikainen
Publikováno v:
Endocrine Connections, Vol 13, Iss 2, Pp 1-11 (2024)
Objective: The associations between adrenal histopathology, lateralization studies, and surgical outcomes in primary aldosteronism remain poorly characterized. We examined the value of immunohistochemical analysis of CYP11B2 for evaluation of adrenal
Externí odkaz:
https://doaj.org/article/ff9273e3ad834d32bb18f6eca2702b67
Autor:
Marja-Riitta Taskinen, Elias Björnson, Niina Matikainen, Sanni Söderlund, Joel Rämö, Mari-Mia Ainola, Antti Hakkarainen, Carina Sihlbom, Annika Thorsell, Linda Andersson, Per-Olof Bergh, Marcus Henricsson, Stefano Romeo, Martin Adiels, Samuli Ripatti, Markku Laakso, Chris J. Packard, Jan Borén
Publikováno v:
JCI Insight, Vol 7, Iss 19 (2022)
Background Apolipoprotein C-III (apoC-III) is a regulator of triglyceride (TG) metabolism, and due to its association with risk of cardiovascular disease, is an emergent target for pharmacological intervention. The impact of substantially lowering ap
Externí odkaz:
https://doaj.org/article/04b0164112e64cf5949fe5d13f341920
Autor:
Rubina Tabassum, Joel T. Rämö, Pietari Ripatti, Jukka T. Koskela, Mitja Kurki, Juha Karjalainen, Priit Palta, Shabbeer Hassan, Javier Nunez-Fontarnau, Tuomo T. J. Kiiskinen, Sanni Söderlund, Niina Matikainen, Mathias J. Gerl, Michal A. Surma, Christian Klose, Nathan O. Stitziel, Hannele Laivuori, Aki S. Havulinna, Susan K. Service, Veikko Salomaa, Matti Pirinen, FinnGen Project, Matti Jauhiainen, Mark J. Daly, Nelson B. Freimer, Aarno Palotie, Marja-Riitta Taskinen, Kai Simons, Samuli Ripatti
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Cardiovascular diseases (CVD) are associated with plasma lipid levels. Here, Tabassum et al. perform genome-wide association studies for lipidomic profiles with 141 (non-standard) lipid species which highlights shared genetic loci with CVD and that t
Externí odkaz:
https://doaj.org/article/a7b6a56d3eec433f97120fae91d896c5
Autor:
Jan Borén, Martin Adiels, Elias Björnson, Niina Matikainen, Sanni Söderlund, Joel Rämö, Marcus Ståhlman, Pietari Ripatti, Samuli Ripatti, Aarno Palotie, Rosellina M. Mancina, Antti Hakkarainen, Stefano Romeo, Chris J. Packard, Marja-Riitta Taskinen
Publikováno v:
JCI Insight, Vol 5, Iss 24 (2020)
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic lipid accumulation. The transmembrane 6 superfamily member 2 (TM6SF2) E167K genetic variant associates with NAFLD and with reduced plasma triglyceride levels in humans. However, the
Externí odkaz:
https://doaj.org/article/0c247ff8398d40deb9bf1ec369f50d80
Autor:
Joel T. Rämö, Pietari Ripatti, Rubina Tabassum, Sanni Söderlund, Niina Matikainen, Mathias J. Gerl, Christian Klose, Michal A. Surma, Nathan O. Stitziel, Aki S. Havulinna, Matti Pirinen, Veikko Salomaa, Nelson B. Freimer, Matti Jauhiainen, Aarno Palotie, Marja‐Riitta Taskinen, Kai Simons, Samuli Ripatti
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 13 (2019)
Background We asked whether, after excluding familial hypercholesterolemia, individuals with high low‐density lipoprotein cholesterol (LDL‐C) or triacylglyceride levels and a family history of the same hyperlipidemia have greater coronary artery
Externí odkaz:
https://doaj.org/article/cf5345777bec45d59bdb177eb68eeeb9
Autor:
Adil Mardinoglu, Elias Bjornson, Cheng Zhang, Martina Klevstig, Sanni Söderlund, Marcus Ståhlman, Martin Adiels, Antti Hakkarainen, Nina Lundbom, Murat Kilicarslan, Björn M Hallström, Jesper Lundbom, Bruno Vergès, Peter Hugh R Barrett, Gerald F Watts, Mireille J Serlie, Jens Nielsen, Mathias Uhlén, Ulf Smith, Hanns‐Ulrich Marschall, Marja‐Riitta Taskinen, Jan Boren
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 3, Pp n/a-n/a (2017)
Abstract To elucidate the molecular mechanisms underlying non‐alcoholic fatty liver disease (NAFLD), we recruited 86 subjects with varying degrees of hepatic steatosis (HS). We obtained experimental data on lipoprotein fluxes and used these individ
Externí odkaz:
https://doaj.org/article/e43610ba34b24032ab9bcfbc35617cd8
Autor:
Pietari Ripatti, Joel T Rämö, Sanni Söderlund, Ida Surakka, Niina Matikainen, Matti Pirinen, Päivi Pajukanta, Antti-Pekka Sarin, Susan K Service, Pirkka-Pekka Laurila, Christian Ehnholm, Veikko Salomaa, Richard K Wilson, Aarno Palotie, Nelson B Freimer, Marja-Riitta Taskinen, Samuli Ripatti
Publikováno v:
PLoS Genetics, Vol 12, Iss 5, p e1006078 (2016)
Familial combined hyperlipidemia (FCH) is a complex and common familial dyslipidemia characterized by elevated total cholesterol and/or triglyceride levels with over five-fold risk of coronary heart disease. The genetic architecture and contribution
Externí odkaz:
https://doaj.org/article/5198904350ad46738f987120e6f61325
Autor:
Niina Matikainen, Elias Björnson, Sanni Söderlund, Christofer Borén, Björn Eliasson, Kirsi H Pietiläinen, Leonie H Bogl, Antti Hakkarainen, Nina Lundbom, Angela Rivellese, Gabriele Riccardi, Jean-Pierre Després, Natalie Alméras, Jens Juul Holst, Carolyn F Deacon, Jan Borén, Marja-Riitta Taskinen
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145890 (2016)
Glucose and lipids stimulate the gut-hormones glucagon-like peptide (GLP)-1, GLP-2 and glucose-dependent insulinotropic polypeptide (GIP) but the effect of these on human postprandial lipid metabolism is not fully clarified.To explore the responses o
Externí odkaz:
https://doaj.org/article/dbd4f7f227364b25bc81385458233bf9
Autor:
Laxman Yetukuri, Sanni Söderlund, Artturi Koivuniemi, Tuulikki Seppänen-Laakso, Perttu S. Niemelä, Marja Hyvönen, Marja-Riitta Taskinen, Ilpo Vattulainen, Matti Jauhiainen, Matej Orešič
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 8, Pp 2341-2351 (2010)
A low level of high density lipoprotein cholesterol (HDL-C) is a powerful risk factor for cardiovascular disease. However, despite the reported key role of apolipo-proteins, specifically, apoA-I, in HDL metabolism, lipid molecular composition of HDL
Externí odkaz:
https://doaj.org/article/07076abf98e14e2a86e3ac30e9546651
Autor:
Shuhei Nakanishi, Riikka Vikstedt, Sanni Söderlund, Miriam Lee-Rueckert, Anne Hiukka, Christian Ehnholm, Mikko Muilu, Jari Metso, Jussi Naukkarinen, Leena Palotie, Petri T. Kovanen, Matti Jauhiainen, Marja-Riitta Taskinen
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 2, Pp 183-192 (2009)
The main antiatherogenic function of HDL is to promote the efflux of cholesterol from peripheral cells and transport it to the liver for excretion in a process termed reverse cholesterol transport. The aim of this study was to evaluate the cholestero
Externí odkaz:
https://doaj.org/article/70430b0ac3304cfbaaca2c33689b2de1