A multimodal marker for cognitive functioning in multiple sclerosis: the role of NfL, GFAP and conventional MRI in predicting cognitive functioning in a prospective clinical cohort

Autor: Maureen van Dam, Brigit A. de Jong, Eline A. J. Willemse, Ilse M. Nauta, Marijn Huiskamp, Martin Klein, Bastiaan Moraal, Sanne de Geus-Driessen, Jeroen J. G. Geurts, Bernard M. J. Uitdehaag, Charlotte E. Teunissen, Hanneke E. Hulst

Publikováno v: Journal of Neurology. D. Steinkopff-Verlag
van Dam, M, de Jong, B A, Willemse, E A J, Nauta, I M, Huiskamp, M, Klein, M, Moraal, B, de Geus-Driessen, S, Geurts, J J G, Uitdehaag, B M J, Teunissen, C E & Hulst, H E 2023, ' A multimodal marker for cognitive functioning in multiple sclerosis : the role of NfL, GFAP and conventional MRI in predicting cognitive functioning in a prospective clinical cohort ', Journal of Neurology, vol. 270, no. 8 . https://doi.org/10.1007/s00415-023-11676-4

Background Cognitive impairment in people with MS (PwMS) has primarily been investigated using conventional imaging markers or fluid biomarkers of neurodegeneration separately. However, the single use of these markers do only partially explain the la

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https://research.vumc.nl/en/publications/0e3777d3-4857-416c-b4fe-dfb2d5a08094