Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Sanne Skovgård, Veidal"'
Autor:
Maria Nicoline Baandrup Kristiansen, Sanne Skovgård Veidal, Christina Christoffersen, Michael Feigh, Niels Vrang, Jonathan David Roth, Mary Erickson, Luciano Adorini, Jacob Jelsing
Publikováno v:
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Compounds in clinical development for nonalcoholic steatohepatitis (NASH) improve liver histopathology in diet-induced obese mouse models of biopsy-confirmed NASH. Since the biopsy section used for histopathological evaluation rep
Externí odkaz:
https://doaj.org/article/e44142f92aa546f5bc09dfe64650bb25
Autor:
Paulus Wohlfart, Michael Feigh, Sanne Skovgård Veidal, Dieter Schmoll, Aimo Kannt, Andreas Nygaard Madsen
Publikováno v:
British Journal of Pharmacology. 178:2412-2423
Background and purpose Activation of hepatic thyroid hormone receptor β (THR-β) is associated with systemic lipid lowering, increased bile acid synthesis, and fat oxidation. In patients with non-alcoholic steatohepatitis (NASH), treatment with THR-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618574cab0d5ae9217a76a7917a18501
https://doi.org/10.1111/bph.15427
https://doi.org/10.1111/bph.15427
Autor:
Patrick C.N. Rensen, Geurt Stokman, Hans M.G. Princen, Michael Feigh, Marta Iruarrizaga-Lejarreta, José W.A. van der Hoorn, Ditte Denker Thorbekk, John J.P. Kastelein, Sanne Skovgård Veidal, Elsbet J. Pieterman, Lars Verschuren, David A. Fraser, Cristina Alonso, Scott L. Friedman, Brittany Basta, Tore Skjaeret, Anita M. van den Hoek, Jimmy F.P. Berbée
Publikováno v:
Liver International
Liver International, 40(11), 2860-2876. WILEY
Liver International, 40(11), 2860-2876. WILEY
Background & Aims While fibrosis stage predicts liver‐associated mortality, cardiovascular disease (CVD) is still the major overall cause of mortality in patients with NASH. Novel NASH drugs should thus ideally reduce both liver fibrosis and CVD. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dde65642a000592115aac1140f902d
https://doi.org/10.1111/liv.14643
https://doi.org/10.1111/liv.14643
Autor:
Niels Vrang, Michele Puglia, Tune H. Pers, Birgitte Rahbek Kornum, Michael Feigh, Helene M Ægidius, Jacob Jelsing, Philip Hallenborg, Sanne Skovgård Veidal, Blagoy Blagoev, Kristoffer T.G. Rigbolt
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Ægidius, H M, Veidal, S S, Feigh, M, Hallenborg, P, Puglia, M, Pers, T H, Vrang, N, Jelsing, J, Kornum, B R, Blagoev, B & Rigbolt, K T G 2020, ' Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis ', Scientific Reports, vol. 10, no. 1, 1148 . https://doi.org/10.1038/s41598-020-58059-7
Scientific Reports
Ægidius, H M, Veidal, S S, Feigh, M, Hallenborg, P, Puglia, M, Pers, T H, Vrang, N, Jelsing, J, Kornum, B R, Blagoev, B & Rigbolt, K T G 2020, ' Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis ', Scientific Reports, vol. 10, no. 1, 1148 . https://doi.org/10.1038/s41598-020-58059-7
Scientific Reports
To improve the understanding of the complex biological processes underlying the development of non-alcoholic steatohepatitis (NASH), a multi-omics approach combining bulk RNA-sequencing based transcriptomics, quantitative proteomics and single-cell R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c55c07b520910373ed7da73108ed82
http://link.springer.com/article/10.1038/s41598-020-58059-7
http://link.springer.com/article/10.1038/s41598-020-58059-7
Autor:
Michael Feigh, Jacob Jelsing, Sanne Skovgård Veidal, Luciano Adorini, Christina Christoffersen, Jonathan D. Roth, Mary Erickson, Niels Vrang, Maria Kristiansen
Publikováno v:
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-11 (2019)
Kristiansen, M N B, Veidal, S S, Christoffersen, C, Feigh, M, Vrang, N, Roth, J D, Erickson, M, Adorini, L & Jelsing, J 2019, ' Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH ', B M C Gastroenterology, vol. 19, no. 1, 228 . https://doi.org/10.1186/s12876-019-1149-z
BMC Gastroenterology
Kristiansen, M N B, Veidal, S S, Christoffersen, C, Feigh, M, Vrang, N, Roth, J D, Erickson, M, Adorini, L & Jelsing, J 2019, ' Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH ', B M C Gastroenterology, vol. 19, no. 1, 228 . https://doi.org/10.1186/s12876-019-1149-z
BMC Gastroenterology
Background Compounds in clinical development for nonalcoholic steatohepatitis (NASH) improve liver histopathology in diet-induced obese mouse models of biopsy-confirmed NASH. Since the biopsy section used for histopathological evaluation represents o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919761ea4372330cd06f0d92d1c6cbb2
https://doaj.org/article/e44142f92aa546f5bc09dfe64650bb25
https://doaj.org/article/e44142f92aa546f5bc09dfe64650bb25
Autor:
Efstathios Vassiliadis, Dorthe Vang Larsen, Rikke Elgaard Clausen, Sanne Skovgård Veidal, Natasha Barascuk, Lise Larsen, Henrik Simonsen, Toni Segovia Silvestre, Christina Hansen, Trine Overgaard, Diana Julie Leeming, Morten A Karsdal
Publikováno v:
Biomarker Insights, Vol 2011, Iss 6, Pp 49-58 (2011)
Externí odkaz:
https://doaj.org/article/b43a7c0dae9244c39ae96a937db82f00
Autor:
Nikolaos Perakakis, Christos S. Mantzoros, Pavlina Chrysafi, Michael Feigh, Sanne Skovgård Veidal
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6332, p 6332 (2021)
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6332, p 6332 (2021)
Empagliflozin, an established treatment for type 2 diabetes (T2DM), has shown beneficial effects on liver steatosis and fibrosis in animals and in humans with T2DM, non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH). However, little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307be0038c4c995eceb3ed2c8e106756
Autor:
Niels Vrang, Fiona Fernandes, Bret R. Sellman, Taylor S. Cohen, Andrey Tovchigrechko, Michael Feigh, Michelle L. Boland, Jacob Jelsing, Jens Nielsen, Sanne Skovgård Veidal, James L. Trevaskis, Henrik H. Hansen, Kirstine S Tølbøl, David E. Tabor, Denise Oró, Paul Warrener, Sebastian T. Thrane
Publikováno v:
World Journal of Gastroenterology
BACKGROUND The trans-fat containing AMLN (amylin liver non-alcoholic steatohepatitis, NASH) diet has been extensively validated in C57BL/6J mice with or without the Lepob/Lepob (ob/ob) mutation in the leptin gene for reliably inducing metabolic and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10727d80256829059ab62239b9213c29
https://doi.org/10.3748/wjg.v25.i33.4904
https://doi.org/10.3748/wjg.v25.i33.4904
Autor:
Malte P. Suppli, Peter Lykke Eriksen, Kristoffer T. G. Rigbolt, Sanne Skovgård Veidal, Hendrik Vilstrup, Karen Louise Thomsen, Fillip Krag Knop, Michael Sørensen, Sara Heebøll
Publikováno v:
Eriksen, P L, Vilstrup, H, Rigbolt, K, Suppli, M P, Sørensen, M, Heebøll, S, Veidal, S S, Knop, F K & Thomsen, K L 2019, ' Non-alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion ', Liver International, vol. 39, no. 11, pp. 2094-2101 . https://doi.org/10.1111/liv.14205
Background & Aims: We recently showed that the functional capacity for ureagenesis is deficient in non-alcoholic fatty liver disease (NAFLD) patients. The aim of this study was to assess expression of urea cycle-related genes to elucidate a possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b6eda02378f2bd02db4dc62ba621a0
https://doi.org/10.1111/liv.14205
https://doi.org/10.1111/liv.14205
Autor:
Konstantinos Stefanakis, Nikolaos Perakakis, Sanne Skovgård Veidal, Christos S. Mantzoros, Michael Feigh
Publikováno v:
Liver international : official journal of the International Association for the Study of the LiverREFERENCES. 41(8)
Background & aims This study aimed to assess and compare the effects of the GLP-1 analog liraglutide and the PPARα/δ agonist elafibranor on liver histology and their impact on hepatic lipidome, metabolome, Kupffer and hepatic stellate cell activati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073265752694c289426b0db0f2f9705c
https://pubmed.ncbi.nlm.nih.gov/33788377
https://pubmed.ncbi.nlm.nih.gov/33788377