Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sanne Moeller Knudsen"'
Autor:
Sanne Moeller Knudsen, Pernille Wismann, Maria Waldhoer, Sarah Norklit Roed, Helle Iversen, Anne Cathrine Nøhr, Hans Bräuner-Osborne
Publikováno v:
Journal of Biological Chemistry. 290:1233-1243
The signaling capacity of seven-transmembrane/G-protein-coupled receptors (7TM/GPCRs) can be regulated through ligand-mediated receptor trafficking. Classically, the recycling of internalized receptors is associated with resensitization, whereas rece
Autor:
Helle Iversen, Nikolaj Kulahin, Hans Bräuner-Osborne, Sarah Noerklit Roed, Karen Arevad Cappelen, Anna Secher, Janne Lehtonen, Jesper Mosolff Mathiesen, Lauge Schäffer, Christina Rye Underwood, Maria Waldhoer, Jacob Hecksher-Soerensen, Jennifer L. Whistler, Pernille Wismann, Sanne Moeller Knudsen
Publikováno v:
Molecular and Cellular Endocrinology. 382:938-949
The glucagon-like peptide-1 incretin receptor (GLP-1R) of family B G protein-coupled receptors (GPCRs) is a major drug target in type-2-diabetes due to its regulatory effect on post-prandial blood-glucose levels. The mechanism(s) controlling GLP-1R m