Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sanne, van Dooremalen"'
Autor:
Ida H. Hiemstra, Kim C.M. Santegoets, Maarten L. Janmaat, Bart E.C.G. De Goeij, Wessel Ten Hagen, Sanne van Dooremalen, Peter Boross, Jeroen van den Brakel, Sieto Bosgra, Grietje Andringa, Berris van Kessel-Welmers, Dennis Verzijl, Richard G. Hibbert, Kristine A. Frerichs, Tuna Mutis, Niels W.C.J. van de Donk, Tahamtan Ahmadi, David Satijn, A. Kate Sasser, Esther C.W. Breij
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104663- (2023)
Summary: Background: HexaBody®-CD38 (GEN3014) is a hexamerization-enhanced human IgG1 that binds CD38 with high affinity. The E430G mutation in its Fc domain facilitates the natural process of antibody hexamer formation upon binding to the cell surf
Externí odkaz:
https://doaj.org/article/f33bd39a5fdd41bc885381f56bdbe832
γ9δ2 T-Cell Expansion and Phenotypic Profile Are Reflected in the CDR3δ Repertoire of Healthy Adults
Autor:
Anna Vyborova, Anke Janssen, Lucrezia Gatti, Froso Karaiskaki, Austin Yonika, Sanne van Dooremalen, Jasper Sanders, Dennis X. Beringer, Trudy Straetemans, Zsolt Sebestyen, Jürgen Kuball
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
γ9δ2T cells fill a distinct niche in human immunity due to the unique physiology of the phosphoantigen-reactive γ9δ2TCR. Here, we highlight reproducible TCRδ complementarity-determining region 3 (CDR3δ) repertoire patterns associated with γ9δ
Externí odkaz:
https://doaj.org/article/dfb5fbd35a32484d8ceb964287caa82a
Autor:
Inez Johanna, Trudy Straetemans, Sabine Heijhuurs, Zsolt Sebestyen, Jürgen Kuball, Eline van Diest, Patricia Hernández López, Angelo D Meringa, Anna Vyborova, Froso Karaiskaki, Jan Gumathi Bormin, Sanne van Dooremalen, Mara J T Nicolasen, Lucrezia C D E Gatti, Dennis X Beringer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/de666a740e2143a1a08f52a3ccd29c36
Autor:
Trudy Straetemans, Anja C.M. de Bruin, Rimke Oostvogels, Wolfgang Uckert, Jürgen Kuball, Sanne van Dooremalen, Tineke Aarts-Riemens, Lovro Kramer, Patricia Hernández-López, Wouter Scheper, Elselien Frijlink, Zsolt Sebestyén, Dennis X. Beringer, Eline van Diest, Guido J. J. Kierkels
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 388-400 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 388-400 (2021)
T cell engineering strategies offer cures to patients and have entered clinical practice with chimeric antibody-based receptors; αβT cell receptor (αβTCR)-based strategies are, however, lagging behind. To allow a more rapid and successful transla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677b56a73c442d2e3fe51c15977b4ccc
http://edoc.mdc-berlin.de/20417/1/20417oa.pdf
http://edoc.mdc-berlin.de/20417/1/20417oa.pdf
Autor:
Sanne van Dooremalen, Jürgen Kuball, Lauri Bloemenkamp, Austin Yonika, Anke Janssen, Dennis X. Beringer
SummaryαβT cells engineered to express a defined γδTCR (TEG) to attack cancer cells have shown great promise when using a γ9δ2TCR to redirect αβT cells (1–9). Reports by us (1–9) and recent reports by others (10, 11) support the key role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b53a4e8004a206273669c4080f4a315e
https://doi.org/10.1101/2021.03.17.435293
https://doi.org/10.1101/2021.03.17.435293
Autor:
Lotte E, van der Wagen, Alberto, Miranda-Bedate, Anke, Janssen, Febilla, Fernando, Nagesha, Appukudige, Sanne, van Dooremalen, Kasper, Westinga, Rick, Admiraal, Magdalena J, Lorenowicz, Gerwin, Huls, Jeroen J W M, Janssen, Annoek E C, Broers, Walter J F M, van der Velden, Rien, van Marwijk Kooy, Mette D, Hazenberg, Colin, de Haar, Caroline, Lindemans, Jaap, Jan Boelens, Jürgen, Kuball
Publikováno v:
Bone marrow transplantation. 55(11)
Autor:
Colin de Haar, Kasper Westinga, Mette D. Hazenberg, Caroline A. Lindemans, Sanne van Dooremalen, Rick Admiraal, Lotte van der Wagen, Jürgen Kuball, Magdalena J. Lorenowicz, Anke Janssen, Jaap Jan Boelens, Walter J.F.M. van der Velden, Febilla Fernando, Nagesha Appukudige, Rien van Marwijk Kooy, Annoek E.C. Broers, Jeroen Janssen, Gerwin Huls, Alberto Miranda-Bedate
Publikováno v:
Bone Marrow Transplantation, 55, 2188-2192
Bone Marrow Transplantation, 55(11), 2188-2192. Nature Publishing Group
Bone marrow transplantation, 55(11), 2188-2192. Nature Publishing Group
van der Wagen, L E, Miranda-Bedate, A, Janssen, A, Fernando, F, Appukudige, N, van Dooremalen, S, Westinga, K, Admiraal, R, Lorenowicz, M J, Huls, G, Janssen, J J W M, Broers, A E C, van der Velden, W J F M, van Marwijk Kooy, R, Hazenberg, M D, de Haar, C, Lindemans, C, Jan Boelens, J & Kuball, J 2020, ' Efficacy of MSC for steroid-refractory acute GVHD associates with MSC donor age and a defined molecular profile ', Bone Marrow Transplantation, vol. 55, no. 11, pp. 2188-2192 . https://doi.org/10.1038/s41409-020-0910-9
Bone Marrow Transplantation, 55, 11, pp. 2188-2192
Bone Marrow Transplantation, 55(11), 2188-2192. Nature Publishing Group
Bone marrow transplantation, 55(11), 2188-2192. Nature Publishing Group
van der Wagen, L E, Miranda-Bedate, A, Janssen, A, Fernando, F, Appukudige, N, van Dooremalen, S, Westinga, K, Admiraal, R, Lorenowicz, M J, Huls, G, Janssen, J J W M, Broers, A E C, van der Velden, W J F M, van Marwijk Kooy, R, Hazenberg, M D, de Haar, C, Lindemans, C, Jan Boelens, J & Kuball, J 2020, ' Efficacy of MSC for steroid-refractory acute GVHD associates with MSC donor age and a defined molecular profile ', Bone Marrow Transplantation, vol. 55, no. 11, pp. 2188-2192 . https://doi.org/10.1038/s41409-020-0910-9
Bone Marrow Transplantation, 55, 11, pp. 2188-2192
Contains fulltext : 229413.pdf (Publisher’s version ) (Closed access)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b48fc123a55f88a9f68c16049df95b
http://hdl.handle.net/2066/229413
http://hdl.handle.net/2066/229413
Autor:
Eline van Diest, Froso Karaiskaki, Dennis X. Beringer, Sanne van Dooremalen, Jürgen Kuball, Zsolt Sebestyén, Jan Gumathi Bormin, Lucrezia C D E Gatti, Trudy Straetemans, Inez Johanna, Anna Vyborova, Sabine Heijhuurs, Patricia Hernández López, Mara J T Nicolasen, Angelo D Meringa
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Backgroundγ9δ2 T cells hold great promise as cancer therapeutics because of their unique capability of reacting to metabolic changes with tumor cells. However, it has proven very difficult to translate this promise into clinical success.MethodsIn o
Autor:
Jeroen van den Brakel, Ida H. Hiemstra, David Satijn, Sanne van Dooremalen, Maarten L. Janmaat, Esther C.W. Breij, Peter Boross, Tahamtan Ahmadi, Bart De Goeij, Laurens P. Kil, Sieto Bosgra, Grietje Andringa, Wessel ten Hagen, A. Kate Sasser
Publikováno v:
Blood. 136:19-20
HexaBody®-CD38 (GEN3014) is a next-generation CD38-specific IgG1 molecule with a hexamerization-enhancing mutation that leads to highly efficient induction of complement-dependent cytotoxicity (CDC) upon binding to CD38 positive tumor cells. HexaBod
Autor:
Paul J. Coffer, Sanne van Dooremalen, Lucienne A. Vonk, Judith Klumperman, Daniel B.F. Saris, Nalan Liv, Magdalena J. Lorenowicz
Publikováno v:
Theranostics, 8(4), 906. Ivyspring International Publisher
Theranostics
Theranostics, 8(4), 906-920. Ivyspring International Publisher
Theranostics
Theranostics, 8(4), 906-920. Ivyspring International Publisher
Osteoarthritis (OA) is a rheumatic disease leading to chronic pain and disability with no effective treatment available. Recently, allogeneic human mesenchymal stromal/stem cells (MSC) entered clinical trials as a novel therapy for OA. Increasing evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01928f10c7ecdceb3dbe4faed4ebc3a4
https://dspace.library.uu.nl/handle/1874/363761
https://dspace.library.uu.nl/handle/1874/363761