Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sanna-Maria Hede"'
Autor:
Inga Nazarenko, Monica Nistér, Mikael S. Lindström, Xiaobing He, Sanna-Maria Hede, James Thompson, Anna Hedrén
Publikováno v:
Upsala Journal of Medical Sciences
The family of platelet-derived growth factors (PDGFs) plays a number of critical roles in normal embryonic development, cellular differentiation, and response to tissue damage. Not surprisingly, as it is a multi-faceted regulatory system, numerous pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0679abec44646d9fe257d9b246b03ac4
http://europepmc.org/articles/PMC3339542
http://europepmc.org/articles/PMC3339542
Autor:
Joakim Lundeberg, Valtteri Wirta, Monica Nistér, Sanna-Maria Hede, Jonas Frisén, Konstantinos Meletis
Publikováno v:
Development. 133:363-369
There is increasing evidence that tumors are heterogeneous and that a subset of cells act as cancer stem cells. Several proto-oncogenes and tumor suppressors control key aspects of stem cell function, suggesting that similar mechanisms control normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0668cb3f73ea00bdc4d75e8a85d277f
https://doi.org/10.1242/dev.02208
https://doi.org/10.1242/dev.02208
Publikováno v:
Oncogene. 33(39)
Proteins involved in promoting cell proliferation and viability need to be timely expressed and carefully controlled for the proper development of the brain but also efficiently degraded in order to prevent cells from becoming brain cancer cells. A m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c039424f08225b653bf3117b1e1c773
https://pubmed.ncbi.nlm.nih.gov/24166497
https://pubmed.ncbi.nlm.nih.gov/24166497
Publikováno v:
Cancer metastasis reviews, vol 32, iss 1-2
Glioma and medulloblastoma represent the most commonly occurring malignant brain tumors in adults and in children respectively. Recent genomic and transcriptional approaches present a complex group of diseases, and delineate a number of molecular sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00639493cd7b8f573675626634faa0ab
https://escholarship.org/uc/item/8qd220g5
https://escholarship.org/uc/item/8qd220g5
Autor:
Maria Jasin, Hildur R. Helgadottir, Pernilla Roswall, Sanna-Maria Hede, Nanna Lindberg, Monica Nistér, Daniel Bråsäter, Lene Uhrbom, Ulrica K. Westermark, Anders Zetterberg
Publikováno v:
Neuro-oncology. 13(12)
Faithful replication and DNA repair are vital for maintenance of genome integrity. RAD51 is a central protein in homologous recombination repair and during replication, when it protects and restarts stalled replication forks. Aberrant RAD51 expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a365ecc0bf298f2d01267f6f121bea
https://pubmed.ncbi.nlm.nih.gov/21926087
https://pubmed.ncbi.nlm.nih.gov/21926087
Publikováno v:
Journal of Oncology, Vol 2011 (2011)
Journal of Oncology
Journal of Oncology
Malignant glioma is the most common brain tumor in adults and is associated with a very poor prognosis. Mutations in the p53 tumor suppressor gene are frequently detected in gliomas. p53 is well-known for its ability to induce cell cycle arrest, apop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e8c44c6552e831f259115223875f4e
https://doaj.org/article/5056f80f35504fdca28e8eaa797757cf
https://doaj.org/article/5056f80f35504fdca28e8eaa797757cf
Autor:
William A. Weiss, Sanna-Maria Hede, Fredrik J. Swartling, Justin Chen, Anders Persson, Vasil Savov, Sara Bolin, Jasmine Lau
Publikováno v:
Cancer Research. 74:3100-3100
MYCN-amplified medulloblastoma is a poor-prognosis childhood brain tumor with unknown cellular origin. Recently, we showed how MYCN overexpression could generate tumors with high penetrance from a glutamate transporter (GLT1) promoter in a transgenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab76466a85ec157588c163b9cd1f05db
https://doi.org/10.1158/1538-7445.am2014-3100
https://doi.org/10.1158/1538-7445.am2014-3100
Autor:
Sara Bolin, William A. Weiss, Vasil Savov, Fredrik J. Swartling, Jasmine Lau, Anders Persson, Sanna-Maria Hede, Justin Chen
Publikováno v:
Cancer Research. 73:357-357
The origin of MYCN-driven medulloblastoma, a poor-prognosis childhood brain tumor is not known. We recently showed that MYCN could generate tumors with high penetrance from a glutamate transporter (GLT1) promoter in a transgenic model (GTML) of medul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5507f0740c64bc0186db66d5d8898be
https://doi.org/10.1158/1538-7445.am2013-357
https://doi.org/10.1158/1538-7445.am2013-357