Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sanna Rauhamäki"'
Autor:
Sanna Rauhamäki, Pekka A. Postila, Sakari Lätti, Sanna Niinivehmas, Elina Multamäki, Klaus R. Liedl, Olli T. Pentikäinen
Publikováno v:
ACS Omega, Vol 3, Iss 6, Pp 6259-6266 (2018)
Externí odkaz:
https://doaj.org/article/a43423e0d23042b8b28d1c60787b00b8
Autor:
Sanna Niinivehmas, Pekka A. Postila, Sanna Rauhamäki, Elangovan Manivannan, Sami Kortet, Mira Ahinko, Pasi Huuskonen, Niina Nyberg, Pasi Koskimies, Sakari Lätti, Elina Multamäki, Risto O. Juvonen, Hannu Raunio, Markku Pasanen, Juhani Huuskonen, Olli T. Pentikäinen
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 743-754 (2018)
A comprehensive set of 3-phenylcoumarin analogues with polar substituents was synthesised for blocking oestradiol synthesis by 17-β-hydroxysteroid dehydrogenase 1 (HSD1) in the latter part of the sulphatase pathway. Five analogues produced ≥62% HS
Externí odkaz:
https://doaj.org/article/ca9ca7ff4f1a4f61961e932f9fb13641
Autor:
Sanna Rauhamäki, Pekka A. Postila, Sanna Niinivehmas, Sami Kortet, Emmi Schildt, Mira Pasanen, Elangovan Manivannan, Mira Ahinko, Pasi Koskimies, Niina Nyberg, Pasi Huuskonen, Elina Multamäki, Markku Pasanen, Risto O. Juvonen, Hannu Raunio, Juhani Huuskonen, Olli T. Pentikäinen
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
Monoamine oxidase B (MAO-B) catalyzes deamination of monoamines such as neurotransmitters dopamine and norepinephrine. Accordingly, small-molecule MAO-B inhibitors potentially alleviate the symptoms of dopamine-linked neuropathologies such as depress
Externí odkaz:
https://doaj.org/article/7ce7e89c445b4b708ee76689792f6021
Autor:
Kanoktip Thammasri, Sanna Rauhamäki, Liping Wang, Artemis Filippou, Violetta Kivovich, Varpu Marjomäki, Stanley J Naides, Leona Gilbert
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67179 (2013)
Human parvovirus B19 (B19V) from the erythrovirus genus is known to be a pathogenic virus in humans. Prevalence of B19V infection has been reported worldwide in all seasons, with a high incidence in the spring. B19V is responsible for erythema infect
Externí odkaz:
https://doaj.org/article/7e8f9ed8c8574a36ab7d12070971ea93
Autor:
Pekka A. Postila, Elina Multamäki, Sanna Niinivehmas, Markku Pasanen, Juhani Huuskonen, Risto O. Juvonen, Pasi Koskimies, Niina Nyberg, Sakari Lätti, Pasi Huuskonen, Hannu Raunio, Sami Kortet, Olli T. Pentikäinen, Mira Ahinko, Elangovan Manivannan, Sanna Rauhamäki
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 743-754 (2018)
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 743-754 (2018)
A comprehensive set of 3-phenylcoumarin analogues with polar substituents was synthesised for blocking oestradiol synthesis by 17-b-hydroxysteroid dehydrogenase 1 (HSD1) in the latter part of the sulphatase pathway. Five analogues produced 62% HSD1 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6286a50cf65022396da43b1badcca946
http://juuli.fi/Record/0330858218
http://juuli.fi/Record/0330858218
Autor:
Moshe Finel, Risto O. Juvonen, Juhani Huuskonen, Olli T. Pentikäinen, Sanna Niinivehmas, Johanna Troberg, Sanna Rauhamäki, Aleksanteri Petsalo, Hannu Raunio, Sami Kortet
Intestinal and hepatic glucuronidation by the UDP-glucuronosyltransferases (UGTs) greatly affect the bioavailability of phenolic compounds. UGT1A10 catalyzes glucuronidation reactions in the intestine, but not in the liver. Here, our aim was to devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377ce476f5ec0cc73c7cb09d06309193
http://urn.fi/URN:NBN:fi:jyu-201803051654
http://urn.fi/URN:NBN:fi:jyu-201803051654
Autor:
Olli T. Pentikäinen, Sanna Rauhamäki, Juhani Huuskonen, Elangovan Manivannan, Sanna Niinivehmas
Publikováno v:
Journal of molecular graphicsmodelling. 64
Utilization of computer-aided molecular discovery methods in virtual screening (VS) is a cost-effective approach to identify novel bioactive small molecules. Unfortunately, no universal VS strategy can guarantee high hit rates for all biological targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35677f6eca86fa198b4ded7d58c12856
https://pubmed.ncbi.nlm.nih.gov/26774287
https://pubmed.ncbi.nlm.nih.gov/26774287
Autor:
Violetta Kivovich, Li Ping Wang, Kanoktip Thammasri, Stanley J. Naides, Varpu Marjomäki, Sanna Rauhamäki, Artemis Filippou, Leona Gilbert
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67179 (2013)
PLoS ONE
PLoS ONE
Human parvovirus B19 (B19V) from the erythrovirus genus is known to be a pathogenic virus in humans. Prevalence of B19V infection has been reported worldwide in all seasons, with a high incidence in the spring. B19V is responsible for erythema infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75cb61d9dadbb76102339968e9056adb
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23776709/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23776709/?tool=EBI
Autor:
Sanna Rauhamäki
Publikováno v:
University of Jyväskylä
The costs of the drug development process are moderated as computer-aided drug design methods are able to expedite the steps required for lead identification. In fact, computational tools are nowadays virtually indispensable from target identificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::63b56010051464761d0a1738764c7b08
http://urn.fi/URN:ISBN:978-951-39-7397-1
http://urn.fi/URN:ISBN:978-951-39-7397-1