Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sanna Pikkusaari"'
Autor:
Anna Perkiö, Barun Pradhan, Fatih Genc, Anna Pirttikoski, Sanna Pikkusaari, Erdogan Pekcan Erkan, Matias Marin Falco, Kaisa Huhtinen, Sara Narva, Johanna Hynninen, Liisa Kauppi, Anna Vähärautio
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Long interspersed nuclear elements (LINE-1s/L1s) are a group of retrotransposons that can copy themselves within a genome. In humans, it is the most successful transposon in nucleotide content. L1 expression is generally mild in normal human
Externí odkaz:
https://doaj.org/article/7262afbd946940dbacc468c1107b3ada
Autor:
Jun Dai, Shuyu Zheng, Matías M. Falco, Jie Bao, Johanna Eriksson, Sanna Pikkusaari, Sofia Forstén, Jing Jiang, Wenyu Wang, Luping Gao, Fernando Perez-Villatoro, Olli Dufva, Khalid Saeed, Yinyin Wang, Ali Amiryousefi, Anniina Färkkilä, Satu Mustjoki, Liisa Kauppi, Jing Tang, Anna Vähärautio
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Exploring non-genetic evolution of cell states during cancer treatments has become attainable by recent advances in lineage-tracing methods. However, transcriptional changes that drive cells into resistant fates may be subtle, necessitating
Externí odkaz:
https://doaj.org/article/cb6fd31ba8b2481198015e55a8c83a4c
Autor:
Pia Roering, Arafat Siddiqui, Vanina D. Heuser, Swapnil Potdar, Piia Mikkonen, Jaana Oikkonen, Yilin Li, Sanna Pikkusaari, Krister Wennerberg, Johanna Hynninen, Seija Grenman, Kaisa Huhtinen, Annika Auranen, Olli Carpén, Katja Kaipio
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectiveA major challenge in the treatment of platinum-resistant high-grade serous ovarian cancer (HGSOC) is lack of effective therapies. Much of ongoing research on drug candidates relies on HGSOC cell lines that are poorly documented. The goal of
Externí odkaz:
https://doaj.org/article/682cdd5529f243d1abfe1e21b24f7510
Autor:
Sanna Pikkusaari, Manuela Tumiati, Anni Virtanen, Jaana Oikkonen, Yilin Li, Fernando Perez-Villatoro, Taru Muranen, Matilda Salko, Kaisa Huhtinen, Anna Kanerva, Heidi Koskela, Johanna Tapper, Riitta Koivisto-Korander, Titta Joutsiniemi, Ulla-Maija Haltia, Heini Lassus, Sampsa Hautaniemi, Anniina Färkkilä, Johanna Hynninen, Sakari Hietanen, Olli Carpén, Liisa Kauppi
Publikováno v:
Clinical Cancer Research. :OF1-OF14
Purpose: Deficiency in homologous recombination (HR) repair of DNA damage is characteristic of many high-grade serous ovarian cancers (HGSC). It is imperative to identify patients with homologous recombination–deficient (HRD) tumors as they are mos
Autor:
Liisa Kauppi, Olli Carpén, Sakari Hietanen, Johanna Hynninen, Anniina Färkkilä, Sampsa Hautaniemi, Heini Lassus, Ulla-Maija Haltia, Titta Joutsiniemi, Riitta Koivisto-Korander, Johanna Tapper, Heidi Koskela, Anna Kanerva, Kaisa Huhtinen, Matilda Salko, Taru Muranen, Fernando Perez-Villatoro, Yilin Li, Jaana Oikkonen, Anni Virtanen, Manuela Tumiati, Sanna Pikkusaari
Comparison of different fHR score cut-off values.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf2368cec2030b2f5e654a9ea7cd9ca
https://doi.org/10.1158/1078-0432.22490492
https://doi.org/10.1158/1078-0432.22490492
Autor:
Liisa Kauppi, Olli Carpén, Sakari Hietanen, Johanna Hynninen, Anniina Färkkilä, Sampsa Hautaniemi, Heini Lassus, Ulla-Maija Haltia, Titta Joutsiniemi, Riitta Koivisto-Korander, Johanna Tapper, Heidi Koskela, Anna Kanerva, Kaisa Huhtinen, Matilda Salko, Taru Muranen, Fernando Perez-Villatoro, Yilin Li, Jaana Oikkonen, Anni Virtanen, Manuela Tumiati, Sanna Pikkusaari
Tumor percentages estimated from H&E images and comparison between HR, ovaHRDScar and Telli2016 status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5165fb84f8b6675c836c0e78cbb3859a
https://doi.org/10.1158/1078-0432.22490483.v1
https://doi.org/10.1158/1078-0432.22490483.v1
Autor:
Liisa Kauppi, Olli Carpén, Sakari Hietanen, Johanna Hynninen, Anniina Färkkilä, Sampsa Hautaniemi, Heini Lassus, Ulla-Maija Haltia, Titta Joutsiniemi, Riitta Koivisto-Korander, Johanna Tapper, Heidi Koskela, Anna Kanerva, Kaisa Huhtinen, Matilda Salko, Taru Muranen, Fernando Perez-Villatoro, Yilin Li, Jaana Oikkonen, Anni Virtanen, Manuela Tumiati, Sanna Pikkusaari
Purpose:Deficiency in homologous recombination (HR) repair of DNA damage is characteristic of many high-grade serous ovarian cancers (HGSC). It is imperative to identify patients with homologous recombination–deficient (HRD) tumors as they are most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576b149b8d2a58ae9d5515d1e7fccb01
https://doi.org/10.1158/1078-0432.c.6533165
https://doi.org/10.1158/1078-0432.c.6533165