Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sanna P. Niinivehmas"'
Autor:
Joanna Małolepsza, Aleksandra Marchwicka, Remigiusz A. Serwa, Sanna P. Niinivehmas, Olli T. Pentikäinen, Edyta Gendaszewska-Darmach, Katarzyna M. Błażewska
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 940-951 (2022)
Rab geranylgeranyltransferase (GGTase-II, RGGT) catalyses the post-translational modification of eukaryotic Rab GTPases, proteins implicated in several pathologies, including cancer, diabetes, neurodegenerative, and infectious diseases. Thus, RGGT in
Externí odkaz:
https://doaj.org/article/47e9fe0a13f242da98a9cbc1518f4bee
Autor:
Elmeri M. Jokinen, Miika Niemeläinen, Sami T. Kurkinen, Jukka V. Lehtonen, Sakari Lätti, Pekka A. Postila, Olli T. Pentikäinen, Sanna P. Niinivehmas
Publikováno v:
Molecules, Vol 28, Iss 8, p 3420 (2023)
Molecular docking is a key method used in virtual screening (VS) campaigns to identify small-molecule ligands for drug discovery targets. While docking provides a tangible way to understand and predict the protein-ligand complex formation, the dockin
Externí odkaz:
https://doaj.org/article/def2c2d7cd9d43a18836191ef31d6b7a
Publikováno v:
International Journal of Molecular Sciences
Negative image-based (NIB) screening is a rigid molecular docking methodology that can also be employed in docking rescoring. During the NIB screening, a negative image is generated based on the target protein’s ligand-binding cavity by inverting i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee608138a56f2b58ebd6d8bb91e08828
https://pubmed.ncbi.nlm.nih.gov/31174295
https://pubmed.ncbi.nlm.nih.gov/31174295