Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Sanna Lehtonen"'
Autor:
Reija Randén-Brady, Timo Carpén, Laura C. Hautala, Tuomas Tolvanen, Caj Haglund, Sakari Joenväärä, Petri Mattila, Antti Mäkitie, Sanna Lehtonen, Jaana Hagström, Suvi Silén
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The increasing incidence of oropharyngeal squamous cell carcinoma (OPSCC) is primarily due to human papillomavirus, and understanding the tumor biology caused by the virus is crucial. Our goal was to investigate the proteins present in the s
Externí odkaz:
https://doaj.org/article/e6c8f9fd31ce44a6ac369bb73e9689a6
Autor:
Rim Bouslama, Vincent Dumont, Sonja Lindfors, Lassi Paavolainen, Jukka Tienari, Harry Nisen, Tuomas Mirtti, Moin A. Saleem, Daniel Gordin, Per-Henrik Groop, Shiro Suetsugu, Sanna Lehtonen
Publikováno v:
Cells, Vol 12, Iss 11, p 1487 (2023)
Changes in the dynamic architecture of podocytes, the glomerular epithelial cells, lead to kidney dysfunction. Previous studies on protein kinase C and casein kinase 2 substrates in neurons 2 (PACSIN2), a known regulator of endocytosis and cytoskelet
Externí odkaz:
https://doaj.org/article/051c46658c344b7d80aa86068b022ab4
Autor:
Mika E. A. Berg, Jette-Britt Naams, Laura C. Hautala, Tuomas A. Tolvanen, Jari P. Ahonen, Sanna Lehtonen, Kristiina Wähälä
Publikováno v:
ACS Omega, Vol 5, Iss 3, Pp 1430-1438 (2020)
Externí odkaz:
https://doaj.org/article/032aa932cb734a2ebf45e493a806158d
Autor:
Luz E. Cabrera, Constanze Schmotz, Moin A. Saleem, Sanna Lehtonen, Olli Vapalahti, Antti Vaheri, Satu Mäkelä, Jukka Mustonen, Tomas Strandin
Publikováno v:
Viruses, Vol 14, Iss 3, p 450 (2022)
Old–world orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS), characterized by acute kidney injury (AKI) with transient proteinuria. It seems plausible that proteinuria during acute HFRS is mediated by the disruption of the glomer
Externí odkaz:
https://doaj.org/article/cba797b420a24d71b68736e9ba121e79
Autor:
Pauliina Saurus, Tuomas A. Tolvanen, Sonja Lindfors, Sara Kuusela, Harry Holthöfer, Eero Lehtonen, Sanna Lehtonen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Lack of CD2-associated protein (CD2AP) in mice increases podocyte apoptosis and leads to glomerulosclerosis and renal failure. We showed previously that SHIP2, a negative regulator of the PI3K/AKT signalling pathway, interacts with CD2AP. He
Externí odkaz:
https://doaj.org/article/d18126741d1541cb94450899dbf983bc
Autor:
Sanna Lehtonen, Barbara Lewko
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/6a69ebd224a84831836e1c1396bc60af
Autor:
Csaba Révész, Anita A. Wasik, Mária Godó, Pál Tod, Sanna Lehtonen, Gábor Szénási, Péter Hamar
Publikováno v:
Biomedicines, Vol 9, Iss 1, p 30 (2021)
Background: Organ protection for transplantation is perfusion with ice-cold preservation solutions, although saline is also used in animal experiments and living donor transplantations. However, ice-cold perfusion can contribute to initial graft inju
Externí odkaz:
https://doaj.org/article/e514b86d5f05467c82bed9999141fd2d
Autor:
Sanna Lehtonen
Publikováno v:
Pharmaceuticals, Vol 13, Iss 12, p 452 (2020)
Metformin is the most commonly prescribed drug for treating type 2 diabetes mellitus (T2D). Its mechanisms of action have been under extensive investigation, revealing that it has multiple cellular targets, either direct or indirect ones, via which i
Externí odkaz:
https://doaj.org/article/87064d6ed5d74130900eae627a8196f4
Publikováno v:
Data in Brief, Vol 6, Iss , Pp 514-520 (2016)
This data article shows the expression levels of specific podocyte injury markers and podocyte slit diaphragm protein nephrin in obese and lean Zucker rat glomeruli. It also contains information on the effect of the overexpression of transcription fa
Externí odkaz:
https://doaj.org/article/75f8e88dc801400da20d4e82ddfafb03
Autor:
Anita A. Wasik, Sanna Lehtonen
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Diabetic kidney disease (DKD) is a major microvascular complication of diabetes and a common cause of end-stage renal disease worldwide. DKD manifests as an increased urinary protein excretion (albuminuria). Multiple studies have shown that insulin r
Externí odkaz:
https://doaj.org/article/6edaf518bdaa4d5baecf100ed42c9ea2