Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sanna Koskiniemi"'
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-10 (2024)
Abstract Dicytostelium firmibasis is a member of Dictyostelia, a group of social amoebae that upon starvation display aggregative multicellularity where the amoebae transition from uni- to multicellular life. The D. firmibasis genome assembly that is
Externí odkaz:
https://doaj.org/article/c2a4034fe92b4b31b855da9e222ec29e
Autor:
Jonas Kjellin, Danna Lee, Hans Steinsland, Rachel Dwane, Oda Barth Vedoy, Kurt Hanevik, Sanna Koskiniemi
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTDiarrheal diseases are still a significant problem for humankind, causing approximately half a million deaths annually. To cause diarrhea, enteric bacterial pathogens must first colonize the gut, which is a niche occupied by the normal bacter
Externí odkaz:
https://doaj.org/article/2fd5f4aeb735487e9b2c86d088909b85
Autor:
Allison M. Jones, Petra Virtanen, Disa Hammarlöf, William J. Allen, Ian Collinson, Christopher S. Hayes, David A. Low, Sanna Koskiniemi
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Many bacterial species interact via direct cell-to-cell contact using CDI systems, which provide a mechanism to inject toxins that inhibit bacterial growth into one another. Here, we find that two CDI toxins, one that depolarizes membranes and anothe
Externí odkaz:
https://doaj.org/article/76773c4bb4574092b66f55466e261feb
Autor:
Magnus Stårsta, Disa L Hammarlöf, Marcus Wäneskog, Susan Schlegel, Feifei Xu, Arvid Heden Gynnå, Malin Borg, Sten Herschend, Sanna Koskiniemi
Publikováno v:
PLoS Genetics, Vol 16, Iss 2, p e1008607 (2020)
RHS elements are components of conserved toxin-delivery systems, wide-spread within the bacterial kingdom and some of the most positively selected genes known. However, very little is known about how Rhs toxins affect bacterial biology. Salmonella Ty
Externí odkaz:
https://doaj.org/article/65c8fb3760a0461a9e0919c17cb181c5
Autor:
Erik Wistrand-Yuen, Michael Knopp, Karin Hjort, Sanna Koskiniemi, Otto G. Berg, Dan I. Andersson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Mutational antibiotic resistance can emerge under either high or low antibiotic levels. Here, the authors show several small-effect resistance mutations are combined to confer high-level resistance in Salmonella enterica exposed to sub-MIC levels of
Externí odkaz:
https://doaj.org/article/81f65f64c61b4ccbb903415fc281cf6f
Autor:
Zachary C. Ruhe, Josephine Y. Nguyen, Jing Xiong, Sanna Koskiniemi, Christina M. Beck, Basil R. Perkins, David A. Low, Christopher S. Hayes
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT Contact-dependent growth inhibition (CDI) systems encode CdiA effectors, which bind to specific receptors on neighboring bacteria and deliver C-terminal toxin domains to suppress target cell growth. Two classes of CdiA effectors that bind di
Externí odkaz:
https://doaj.org/article/6c77590bbaf34ce5bd811392d96d7a98
Autor:
Sanna Koskiniemi, Fernando Garza-Sánchez, Natasha Edman, Swarnava Chaudhuri, Stephen J Poole, Colin Manoil, Christopher S Hayes, David A Low
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120265 (2015)
Contact-dependent growth inhibition (CDI) is a mode of inter-bacterial competition mediated by the CdiB/CdiA family of two-partner secretion systems. CdiA binds to receptors on susceptible target bacteria, then delivers a toxin domain derived from it
Externí odkaz:
https://doaj.org/article/bd7d17f491ec4dfda3e915bcaaaa394b
Autor:
Sanna Koskiniemi, Fernando Garza-Sánchez, Linus Sandegren, Julia S Webb, Bruce A Braaten, Stephen J Poole, Dan I Andersson, Christopher S Hayes, David A Low
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004255 (2014)
Clonally derived bacterial populations exhibit significant genotypic and phenotypic diversity that contribute to fitness in rapidly changing environments. Here, we show that serial passage of Salmonella enterica serovar Typhimurium LT2 (StLT2) in bro
Externí odkaz:
https://doaj.org/article/c7e633e8bcad43d6b353b0ba9a9a02a6
Autor:
Sanna Koskiniemi, Henry S Gibbons, Linus Sandegren, Naeem Anwar, Gary Ouellette, Stacey Broomall, Mark Karavis, Paul McGregor, Alvin Liem, Ed Fochler, Lauren McNew, Carolyn Nicole Rosenzweig, Mikael Rhen, Evan W Skowronski, Dan I Andersson
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70147 (2013)
How pathogenic bacteria adapt and evolve in the complex and variable environment of the host remains a largely unresolved question. Here we have used whole genome sequencing of Salmonella enterica serovar Typhimurium LT2 populations serially passaged
Externí odkaz:
https://doaj.org/article/32d286fab7f649d5b340ff9c0ec1e094
Publikováno v:
PLoS Genetics, Vol 8, Iss 6, p e1002787 (2012)
Gene loss by deletion is a common evolutionary process in bacteria, as exemplified by bacteria with small genomes that have evolved from bacteria with larger genomes by reductive processes. The driving force(s) for genome reduction remains unclear, a
Externí odkaz:
https://doaj.org/article/299ab381f8884bb3a2f52f4f947095e4