Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sanna Kettunen"'
Autor:
Sanna Kettunen, Tuisku Suoranta, Sadegh Beikverdi, Minja Heikkilä, Anna Slita, Iida Räty, Elias Ylä-Herttuala, Katariina Öörni, Anna-Kaisa Ruotsalainen, Seppo Ylä-Herttuala
Publikováno v:
Cells, Vol 13, Iss 11, p 983 (2024)
The 9p21.3 genomic locus is a hot spot for disease-associated single-nucleotide polymorphisms (SNPs), and its strongest associations are with coronary artery disease (CAD). The disease-associated SNPs are located within the sequence of a long noncodi
Externí odkaz:
https://doaj.org/article/da168086675543719c8c3c3303973a12
Autor:
Elias Ylä-Herttuala, Taina Vuorio, Sanna Kettunen, Svetlana Laidinen, Seppo Ylä-Herttuala, Timo Liimatainen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The role of cardiac lymphatics in the pathogenesis of myocardial infarction (MI) is unclear. Lymphatic system regulates cardiac physiological processes such as edema and tissue fluid balance, which affect MI pathogenesis. Recently, MI and fi
Externí odkaz:
https://doaj.org/article/287bce11a6584195874c2bbec6a455a7
Autor:
Sanna Kettunen, Anna-Kaisa Ruotsalainen, Tiit Örd, Tuisku Suoranta, Janne Heikkilä, Minna U. Kaikkonen, Nihay Laham-Karam, Seppo Ylä-Herttuala
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundSeveral genome-wide association studies have reported a risk locus for coronary artery disease (CAD) in the 9p21. 3 chromosomal region. This region encodes a lncRNA in the INK4 locus (ANRIL) and its genetic variance has a strong association
Externí odkaz:
https://doaj.org/article/e934ae1623cc4392a9b8ba107aa76995
Autor:
Erika Gurzeler, Anna-Kaisa Ruotsalainen, Anssi Laine, Teemu Valkama, Sanna Kettunen, Markku Laakso, Seppo Ylä-Herttuala
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Background and aims Diabetes is a major risk factor of atherosclerosis and its complications. The loss-of-function mutation E1506K in the sulfonylurea receptor 1 (SUR1-E1506K) induces hyperinsulinemia in infancy, leading to impaired glucose tolerance
Externí odkaz:
https://doaj.org/article/95ff50082cac4d4ab98c60aaa8e93e1f
Autor:
Guido R.Y. De Meyer, Sanna Kettunen, Emmi Kokki, Tommi Karttunen, Seppo Ylä-Herttuala, Kati Kinnunen
Publikováno v:
Current trends in ophthalmology
Aim: Transgenic mice with an elastic fiber mutation (C1039G+/-) in the fibrillin-1 gene and apolipoprotein E deficiency express vulnerable atherosclerotic plaque formation in the aorta and coronary and carotid arteries. The fibrillin-1 gene mutation
Autor:
Krista Hokkanen, Henri Niskanen, Seppo Ylä-Herttuala, Philip L.S.M. Gordts, Sanna Kettunen, Hanne Laakso, Matti Jauhiainen, Annakaisa Tirronen, Minna U. Kaikkonen, Taina Vuorio, Bastian Ramms
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Objective— Dyslipidemia is one of the key factors behind coronary heart disease. Blood and lymphatic vessels play pivotal roles in both lipoprotein metabolism and development of atherosclerotic plaques. Recent studies have linked members of VEGF (v
Autor:
Sanna Kettunen, Seppo Ylä-Herttuala, Muhammad Arsalan Khan, Tommi Heikura, Hanne Laakso, Svetlana Laidinen, Timo Liimatainen
Publikováno v:
NMR in Biomedicine. 31:e3871
Magnetic resonance rotating frame relaxation times are an alternative non-contrast agent choice for the diagnosis of chronic myocardial infarct. Fibrosis typically occurs in progressive hypertrophic cardiomyopathy. Fibrosis has been imaged in myocard
Publikováno v:
Journal of the neurological sciences. 116(1)
The predictive value of serum cortisol level on the prognosis in acute brain infarction of the carotid circulation territory was studied in 101 patients younger than 70 years. The levels of 7 a.m. and 7 p.m. serum cortisol were measured initially and
Publikováno v:
Current Opinion in Cardiology.
Atherosclerosis, characterized by lipid accumulation and chronic inflammation in the arterial wall, is the leading causes of death worldwide. The purpose of this article is to review the status of RNA interference (RNAi) based therapies in clinical t