Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sanna Hellberg"'
Autor:
Ashok Kumar Kumawat, Mulugeta M. Zegeye, Geena Varghese Paramel, Roland Baumgartner, Anton Gisterå, Obed Amegavie, Sanna Hellberg, Hong Jin, April S. Caravaca, Leif Å. Söderström, Lindvi Gudmundsdotter, Fredrik Y. Frejd, Liza U. Ljungberg, Peder S. Olofsson, Daniel F. J. Ketelhuth, Allan Sirsjö
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
The balance between pro- and anti-inflammatory cytokines released by immune and non-immune cells plays a decisive role in the progression of atherosclerosis. Interleukin (IL)-17A has been shown to accelerate atherosclerosis. In this study, we investi
Externí odkaz:
https://doaj.org/article/a008b8877cff40138fe7b07965ae20bc
VEGF‐B‐induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart
Autor:
Riikka Kivelä, Maija Bry, Marius R Robciuc, Markus Räsänen, Miia Taavitsainen, Johanna MU Silvola, Antti Saraste, Juha J Hulmi, Andrey Anisimov, Mikko I Mäyränpää, Jan H Lindeman, Lauri Eklund, Sanna Hellberg, Ruslan Hlushchuk, Zhen W Zhuang, Michael Simons, Valentin Djonov, Juhani Knuuti, Eero Mervaala, Kari Alitalo
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 3, Pp 307-321 (2014)
Abstract Angiogenic growth factors have recently been linked to tissue metabolism. We have used genetic gain‐ and loss‐of function models to elucidate the effects and mechanisms of action of vascular endothelial growth factor‐B (VEGF‐B) in th
Externí odkaz:
https://doaj.org/article/ebec774a221a4674a5d3e1c1b7a80b29
Autor:
Sanna Hellberg, Johanna M.U. Silvola, Heidi Liljenbäck, Max Kiugel, Olli Eskola, Harri Hakovirta, Sohvi Hörkkö, Veronique Morisson-Iveson, Ella Hirani, Pekka Saukko, Seppo Ylä-Herttuala, Juhani Knuuti, Antti Saraste, Anne Roivainen
Publikováno v:
Molecules, Vol 24, Iss 6, p 1072 (2019)
Atherosclerosis is characterized by the accumulation of oxidized lipids in the artery wall, which triggers an inflammatory response. Oxidized low-density lipoprotein (ox-LDL) presents amyloid-like structural properties, and different amyloid species
Externí odkaz:
https://doaj.org/article/79295f815bc244cd97f29c8ee3caf1a0
Autor:
Max Kiugel, Sanna Hellberg, Meeri Käkelä, Heidi Liljenbäck, Tiina Saanijoki, Xiang-Guo Li, Johanna Tuomela, Juhani Knuuti, Antti Saraste, Anne Roivainen
Publikováno v:
Molecules, Vol 23, Iss 12, p 3168 (2018)
Background: The expression of matrix metalloproteinases 2/9 (MMP-2/9) has been implicated in arterial remodeling and inflammation in atherosclerosis. We evaluated a gallium-68 labeled peptide for the detection of MMP-2/9 in atherosclerotic mouse aort
Externí odkaz:
https://doaj.org/article/bebb0c2dfdc549f68bf837d20f499388
Autor:
Sanna Hellberg, Osman Ahmed, Yuyang Zhang, Giada Di Nunzio, Hanna M Björck, Roy Francis, Linn Fagerberg, Anton Gisterå, Xueming Zhang, Jari Metso, Valentina Manfé, Yosdel Soto, Anders Franco-Cereceda, Per Eriksson, Matti Jauhiainen, Peder S. Olofsson, Stephen G. Malin
Apolipoprotein-B (APOB) containing lipoproteins are causative for atherosclerotic cardiovascular disease. Whether the vasculature is the initial responding site or if atherogenic-dyslipidemia effects other organs simultaneously is unknown. We set out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2698f270010d9aa1764311ad0c4afc65
https://doi.org/10.1101/2022.10.13.512086
https://doi.org/10.1101/2022.10.13.512086
Autor:
Sanna Hellberg, Seppo Ylä-Herttuala, Juhani Knuuti, Anne Roivainen, Pirjo Nuutila, Mia Ståhle, Jenni Virta, Olli Metsälä, Heidi Liljenbäck, Xiang-Guo Li, Pekka Saukko, Matti Jauhiainen, Antti Saraste
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 320:E989-E998
Cardiovascular effects of glucagon-like peptide-1 receptor (GLP-1R) agonist therapies are potentially mediated by anti-inflammatory effects on atherosclerosis. Our study demonstrates that 68Ga-NODAGA-exendin-4, a radioligand specifically targeting GL
Autor:
Johanna M. U. Silvola, Pirjo Nuutila, Jenni Virta, Antti Saraste, Juhani Knuuti, Mirva Söderström, Heidi Liljenbäck, Mia Ståhle, Sanna Hellberg, Maria F. Gomez, Jenni Huusko, Seppo Ylä-Herttuala, Anne Roivainen
Publikováno v:
Atherosclerosis. 305:64-72
Background and aims Dipeptidyl peptidase 4 (DPP-4) inhibitors have anti-inflammatory and atheroprotective effects. We evaluated the effects of the DPP-4 inhibitor linagliptin on atherosclerotic plaque and hepatic inflammation using histology and 2-de
Autor:
Ashok Kumar, Kumawat, Mulugeta M, Zegeye, Geena Varghese, Paramel, Roland, Baumgartner, Anton, Gisterå, Obed, Amegavie, Sanna, Hellberg, Hong, Jin, April S, Caravaca, Leif Å, Söderström, Lindvi, Gudmundsdotter, Fredrik Y, Frejd, Liza U, Ljungberg, Peder S, Olofsson, Daniel F J, Ketelhuth, Allan, Sirsjö
Publikováno v:
Frontiers in cardiovascular medicine. 9
The balance between pro- and anti-inflammatory cytokines released by immune and non-immune cells plays a decisive role in the progression of atherosclerosis. Interleukin (IL)-17A has been shown to accelerate atherosclerosis. In this study, we investi
Autor:
Mia, Ståhle, Sanna, Hellberg, Jenni, Virta, Heidi, Liljenbäck, Olli, Metsälä, Xiang-Guo, Li, Matti, Jauhiainen, Pekka, Saukko, Seppo, Ylä-Herttuala, Pirjo, Nuutila, Juhani, Knuuti, Antti, Saraste, Anne, Roivainen
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 320(5)
Cardiovascular effects of glucagon-like peptide-1 receptor (GLP-1R) agonist therapies are potentially mediated by anti-inflammatory effects on atherosclerosis. Our study demonstrates that
Autor:
Peder S. Olofsson, Sanna Hellberg, Matti Jauhiainen, Jari Metso, Stephen Malin, Quan-Zhen Li, Guangchun Chen, Valentina Manfè, Vladimir S. Shavva, Christoph J. Binder
Atherosclerosis is thought to be initiated by the sub-intimal retention of apolipoprotein-B containing lipoproteins within susceptible sites of the vasculature. Understanding this initiation is not possible with current legacy mouse models of atheros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d7c04fc9c375d8991b07868dab72a46
https://doi.org/10.1101/2020.09.02.279596
https://doi.org/10.1101/2020.09.02.279596