Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Sanna Goyert"'
2
CD14 is a member of the family of leucine-rich proteins and is encoded by a gene syntenic with multiple receptor genes
Autor: Ferrero, E., Hsieh, C. -L, Francke, U., Sanna Goyert
Publikováno v: Scopus-Elsevier
We have isolated and characterized genomic and cDNA clones encoding the murine homolog of the human monocyte/granulocyte cell surface glycoprotein, CD14. As in man, the expression of murine CD14 is limited to the myeloid lineage. The murine and human
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e2d08ab057bb5d9466bf972184bfd5
https://doi.org/10.4049/jimmunol.145.1.331
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3
Cutting edge: Toll-like receptor (TLR)2- and TLR4-mediated pathogen recognition in resistance to airborne infection with Mycobacterium tuberculosis
Autor: Alexandra Fehrenbach, Norbert Reiling, Carsten J. Kirschning, Svenja Kröger, Sanna Goyert, Christoph Hölscher, Stefan Ehlers
Publikováno v: Scopus-Elsevier
Innate resistance against Mycobacterium tuberculosis is thought to depend critically on engagement of pattern recognition receptors on macrophages. However, the relative contribution of these receptors for containing M. tuberculosis infection has rem
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d66510f384dd185aff6e899175ea32
https://pubmed.ncbi.nlm.nih.gov/12244136
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4
Innate immune responses differ in baboons, chimpanzees and humans. (170.18)
Autor: Jessica Brinkworth, Kate Pechenkina, Jack Silver, Sanna Goyert
Publikováno v: The Journal of Immunology. 186:170.18-170.18
Innate immunity is the first host defense against invading pathogens and involves the activation of immune cells via Toll-like receptors (TLRs). As close human relatives sharing genomic identity, chimpanzees (98.6%) and baboons (~92%) are important b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4a1b990e1f80e0c1f5a762883c49626
https://doi.org/10.4049/jimmunol.186.supp.170.18
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5
Differential expression of two pathways of chemokine induction protect CD14- and TLR4-deficient mice from localized E. coli infections (94.16)
Autor: Sanna Goyert, Shalaka Metkar, Kwang Kim, Jack Silver
Publikováno v: The Journal of Immunology. 184:94.16-94.16
Sepsis, characterized by a systemic bacterial infection, is a life-threatening condition that can lead to multi-organ failure and death from septic shock. We have observed that CD14- and TLR4-deficient mice are resistant to death by sepsis from sever
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37234e13d7034e57ebebe756a905757a
https://doi.org/10.4049/jimmunol.184.supp.94.16
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6
Antigen-presenting capabilities of human monocytes correlates with their expression of HLA-DS, an Ia determinant distinct from HLA-DR
Autor: Gonwa, T. A., Picker, L. J., Raff, H. V., Sanna Goyert, Silver, J., Stobo, J. D.
Publikováno v: Scopus-Elsevier
Utilizing a monoclonal antibody (Mac-120) specific for 40 to 60% of peripheral blood adherent mononuclear cells (M phi), we were able to separate M phi into two populations based on their reactivity with the antibody. Both populations, Mac-120+ and M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a4ae02746675aa251238d6a57e17a8
https://doi.org/10.4049/jimmunol.130.2.706
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9
CD14-independent responses to LPS require a serum factor that is absent from neonates
Autor: Cohen, L., Haziot, A., Ding Ren Shen, Lin, X. -Y, Sia, C., Harper, R., Silver, J., Sanna Goyert
Publikováno v: Scopus-Elsevier
Europe PubMed Central
Monocytes/macrophages and neutrophils can respond to endotoxin via a high-affinity receptor (CD14), requiring low levels of LPS (< 1 ng/ml) as well as through another pathway(s) that requires high levels of LPS (> 10 ng/ml). Both pathways result in t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97ec371f0de6e7210232d9b1f74fc7f
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028874439&partnerID=MN8TOARS
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10
The monocyte differentiation antigen, CD14, is anchored to the cell membrane by a phosphatidylinositol linkage
Autor: Haziot, A., Chen, S., Ferrero, E., Low, M. G., Silber, R., Sanna Goyert
Publikováno v: Scopus-Elsevier
Europe PubMed Central
CD14 is a myeloid differentiation Ag expressed primarily on peripheral blood monocytes and macrophages. Although its function is unknown, the CD14 gene maps to a region encoding several myeloid growth factors and receptors. Analysis of the CD14 prote
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4a2dfb407f8ea1eadab9cabb5c3512
http://www.scopus.com/inward/record.url?eid=2-s2.0-0023687039&partnerID=MN8TOARS
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