Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Sanna, Oikari"'
Autor:
Nina Höglund, Heini Rossi, Hanna-Maaria Javela, Sanna Oikari, Petteri Nieminen, Anne-Mari Mustonen, Niina Airas, Vesa Kärjä, Anna Mykkänen
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-11 (2024)
Abstract Background Equine asthma (EA) is a chronic lower airway inflammation that leads to structural and functional changes. Hyaluronic acid (HA) has crucial functions in the extracellular matrix homeostasis and inflammatory mediator activity. HA c
Externí odkaz:
https://doaj.org/article/ac89b01b76b74a57a1d70b0ca1792183
Autor:
Anne-Mari Mustonen, Nina Lehmonen, Sanna Oikari, Janne Capra, Marja Raekallio, Anna Mykkänen, Tommi Paakkonen, Kirsi Rilla, Tytti Niemelä, Petteri Nieminen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Osteoarthritis (OA) is a degenerative joint disease with inadequately understood pathogenesis leading to pain and functional limitations. Extracellular vesicles (EVs) released by synovial joint cells can induce both pro- and anti-OA effects.
Externí odkaz:
https://doaj.org/article/a36d9259827c4c89bc26e97231e52563
Autor:
Anne-Mari Mustonen, Janne Capra, Kirsi Rilla, Petri Lehenkari, Sanna Oikari, Tommi Kääriäinen, Antti Joukainen, Heikki Kröger, Tommi Paakkonen, Johanna Matilainen, Petteri Nieminen
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Hyaluronic acid (HA) is the major extracellular matrix glycosaminoglycan with a reduced synovial fluid (SF) concentration in arthropathies. Cell-derived extracellular vesicles (EV) have also been proposed to contribute to pathogen
Externí odkaz:
https://doaj.org/article/89c9f8d37bee4a819b7b9812c189bc41
Autor:
Nina Höglund, Ninna Koho, Heini Rossi, Jenni Karttunen, Anne-Mari Mustonen, Petteri Nieminen, Kirsi Rilla, Sanna Oikari, Anna Mykkänen
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Extracellular vesicles (EVs) are membrane-bound particles that engage in inflammatory reactions by mediating cell–cell interactions. Previously, EVs have been isolated from the bronchoalveolar lavage fluid (BALF) of humans and rodents. The aim of t
Externí odkaz:
https://doaj.org/article/862bd0a774c249bfb0bcd26771ea3d55
Autor:
Niina Aaltonen, Heikki Kyykallio, Sylvain Tollis, Janne Capra, Jaana M. Hartikainen, Johanna Matilainen, Sanna Oikari, Kirsi Rilla
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Invasion of tumor cells through the stroma is coordinated in response to migratory cues provided by the extracellular environment. One of the most abundant molecules in the tumor microenvironment is hyaluronan, a glycosaminoglycan known to promote ma
Externí odkaz:
https://doaj.org/article/92b948174c084ac7a980ffd774144269
Autor:
Kai Härkönen, Sanna Oikari, Heikki Kyykallio, Janne Capra, Sini Hakkola, Kirsi Ketola, Uma Thanigai Arasu, George Daaboul, Andrew Malloy, Carla Oliveira, Otto Jokelainen, Reijo Sironen, Jaana M. Hartikainen, Kirsi Rilla
Publikováno v:
Cells, Vol 8, Iss 3, p 276 (2019)
CD44 is a multifunctional adhesion molecule typically upregulated in malignant, inflamed and injured tissues. Due to its ability to bind multiple ligands present in the tumor microenvironment, it promotes multiple cellular functions related to tumori
Externí odkaz:
https://doaj.org/article/1f935e40bb864eb1950432ca6fa63532
Autor:
Anne-Mari Mustonen, Tommi Paakkonen, Johanna Matilainen, Kirsi Rilla, Reijo Käkelä, Marjo Malinen, Piia Takabe, Sanna Oikari, Janne Capra, Sanna P. Sihvo, Pauliina Ryökäs, Petteri Nieminen
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5613
Extracellular vesicles (EVs) function as conveyors of fatty acids (FAs) and other bioactive lipids and can modulate the gene expression and behavior of target cells. EV lipid composition influences the fluidity and stability of EV membranes and refle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa22e4a7f33fc303a3b42efc4e6fbdf
https://pubmed.ncbi.nlm.nih.gov/35628422
https://pubmed.ncbi.nlm.nih.gov/35628422
Autor:
Kirsi Kainulainen, Piia Takabe, Sami Heikkinen, Niina Aaltonen, Carol de la Motte, Leena Rauhala, Franziska C. Durst, Sanna Oikari, Taija Hukkanen, Eija Rahunen, Ella Ikonen, Jaana M. Hartikainen, Kirsi Ketola, Sanna Pasonen-Seppänen
Publikováno v:
The Journal of investigative dermatology. 142(11)
The tumor microenvironment, with distinctive cell types and a complex extracellular matrix has a tremendous impact on cancer progression. In this study, we investigated the effects of proinflammatory (M1) and immunosuppressive (M2) macrophages on hya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900f777ae22e8727f337e05da5eb6e82
https://pubmed.ncbi.nlm.nih.gov/35580697
https://pubmed.ncbi.nlm.nih.gov/35580697
Autor:
Mazen Sudah, Amro Masarwah, Markku Tammi, Päivi Auvinen, Juho Ikonen, Anna Sutela, Satu Tiainen, Ritva Vanninen, Kirsi Rilla, Kirsi Hämäläinen, Sanna Oikari, Raija Tammi
Publikováno v:
Breast Cancer Research and Treatment
Purpose Tumor microenvironment, including inflammatory cells, adipocytes and extracellular matrix constituents such as hyaluronan (HA), impacts on cancer progression. Systemic metabolism also influences tumor growth e.g. obesity and type 2 diabetes (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9dd27a5f65b5d8313f1bbd6f4b52db
https://doi.org/10.1007/s10549-019-05491-7
https://doi.org/10.1007/s10549-019-05491-7
Autor:
Annele Sainio, Hannu Järveläinen, Piia Takabe, Markku Koulu, Mirva Söderström, Sanna Oikari, Henriikka Salomäki-Myftari, Sanna Pasonen-Seppänen
Publikováno v:
Journal of Investigative Medicine
Metformin is the first-line drug in the treatment of type 2 diabetes worldwide based on its effectiveness and cardiovascular safety. Currently metformin is increasingly used during pregnancy in women with gestational diabetes mellitus, even if the lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2de9fd689345caf55484c83990b91b3
http://europepmc.org/articles/PMC7063400
http://europepmc.org/articles/PMC7063400