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Wheat Germ Supplementation Attenuates Obesity-Induced Neuroinflammation in the RVLM of IL-10 KO mice

Autor: Ashley Di Agostino, Bhuvana Plakkot, Raisa Monteiro, Mahesh Sivasubramanian, Sanmi Alake, Edralin Lucas, Madhan Subramanian

Publikováno v: Physiology. 38

Obesity is known to be a major factor in the increase of cardiovascular risk and inflammatory responses in the brain. It has been found that high-fat diet (HFD)-induced obesity increases sympathetic nerve activity (SNA) through a cascade of chronic m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75ae343296d7675013f8ed9547f4a95d
https://doi.org/10.1152/physiol.2023.38.s1.5731095

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Montmorency Tart Cherry Supplementation Has Modest Effects on the Gut Microbiome and Markers of Gut Integrity and Insulin Resistance in Mice Fed Western Diet

Autor: Brenda J. Smith, Guadalupe Davila-El Rassi, Edralin A. Lucas, Dingbo Lin, Sanmi Alake, Babajide Ojo, Siau Yen Wong, Amritpal Kaur, Madison Pastor

Publikováno v: Curr Dev Nutr

OBJECTIVES: This study investigated the dose-dependent effects of freeze-dried Montmorency tart cherry (TC) supplementation on gut health and metabolic parameters in mice fed a western diet (WD). METHODS: Six-week-old male C57BL/6 mice were randomly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae8f65ad6bc39de99149593f50631a4
https://europepmc.org/articles/PMC8265449/

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Wheat Germ Supplementation Improves Glucose Homeostasis Markers of Overweight Adults Independent of Gut Microbial Modulation

Autor: Madison Dixon, Edralin A. Lucas, John Ice, Guadalupe Davila-El Rassi, Sam R. Emerson, Levin Dotimas, Babajide Ojo, Sanmi Alake, Amritpal Kaur, Jiangchao Zhao

Publikováno v: Curr Dev Nutr

OBJECTIVES: This study investigated the effects of wheat germ (WG) supplementation on inflammation, metabolic, and gut health markers in overweight adults. METHODS: Forty overweight (BMI = 25.0–30 kg/m(2)) adults between 18–45 y old were recruite

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8218c491a1c566cfec4420d51d72fcc4
https://europepmc.org/articles/PMC8180943/

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Loss of Interleukin (IL)-10 Is Associated With Increased Vascular Inflammation and Sex-Differences in Metabolic Outcomes of Normal Diet-Fed Mice

Autor: John Ice, Brenda J. Smith, Winyoo Chowanadisai, Amritpal Kaur, Evan Hermann, Edralin A. Lucas, Sanmi Alake, Dingbo Lin, Babajide Ojo

Publikováno v: Curr Dev Nutr

OBJECTIVES: The anti-inflammatory cytokine, IL-10, plays an important role in reducing the risk of many inflammatory diseases. This study investigated the time and sex effects of IL-10 gene deletion on metabolic risk factors that contribute to the de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006b57b493d7cfdd9e2d6da1d35eaf45
https://europepmc.org/articles/PMC8181497/

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Supplemental Wheat Germ Activates the STAT3-Reg3 Pathway in the Gut and Attenuates the Lipopolysaccharide Binding Protein Gene in the Adipose Tissue of Mice Fed a Western Diet

Autor: Sanmi Alake, Babajide Ojo, Amritpal Kaur, Siau Yen Wong, Bryant Keirns, Jerry Ritchey, Winyoo Chowanadisai, Edralin Lucas, Stephen Clarke, Brenda Smith

Publikováno v: Curr Dev Nutr

OBJECTIVES: This study investigated the effects of wheat germ (WG) on gut antimicrobial peptides (AMPs, i.e., regenerating islet-derived protein [Reg] 3 g and Reg3b) in the jejunum and its potential to inhibit nuclear factor kappa-light-chain-enhance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f949a9fe6cb8cdc5766ce1d18ef513d6
https://europepmc.org/articles/PMC7259195/

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The Effects of Wheat Germ Supplementation on Anthropometric, Biochemical, and Stool Measures in Overweight Adults

Autor: Sanmi Alake, Sam R. Emerson, Madison Dixon, Babajide Ojo, Edralin A. Lucas, Amritpal Kaur, Levin Dotimas, Winyoo Chowanadisai

Publikováno v: Curr Dev Nutr

OBJECTIVES: This study investigated the effects of a 4-week wheat germ supplementation on anthropometric, biochemical, and stool measures in overweight adults. METHODS: Forty overweight (body mass index = 25.0–30 kg/m(2)) adults (18–45 years old)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02a6242736d74661308c98be05b68b5
https://europepmc.org/articles/PMC7257647/

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Pinto beans modulate the gut microbiome, augment MHC II protein, and antimicrobial peptide gene expression in mice fed a normal or western-style diet

Autor: Bryant H. Keirns, Winyoo Chowanadisai, Matthew D. Hart, Babajide Ojo, Edralin A. Lucas, Guadalupe Davila El-Rassi, Jerry W. Ritchey, Grace Gallucci, Stephen L. Clarke, Peiran Lu, Dingbo Lin, Kendall L Anderson, Brenda J. Smith, Sanmi Alake

Publikováno v: The Journal of nutritional biochemistry. 88

The onset of type 2 diabetes in obesity is associated with gut dysbiosis and a failure to confine commensal bacteria and toxins to the gut lumen while prebiotics may prevent these effects. This study evaluated the effects of pinto beans (PB) suppleme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a13c7c8455f9f1420aca3d4485749c6
https://pubmed.ncbi.nlm.nih.gov/33144228

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