Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sanlan Li"'
Autor:
Wei Gu, Xiaofeng Huang, Pratik N. P. Singh, Sanlan Li, Ying Lan, Min Deng, Lauretta A. Lacko, Jesus M. Gomez-Salinero, Shahin Rafii, Michael P. Verzi, Ramesh A. Shivdasani, Qiao Zhou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Plasticity among cell lineages is a fundamental, but poorly understood, property of regenerative tissues. In the gut tube, the small intestine absorbs nutrients, whereas the colon absorbs electrolytes. In a striking display of inherent plast
Externí odkaz:
https://doaj.org/article/040c31972788465f824261ca65f6d92f
Autor:
Fei Liu, Yijie Zhang, Fuliang Chen, Jiacheng Yuan, Sanlan Li, Sue Han, Dengyu Lu, Junlan Geng, Zhiping Rao, Li Sun, Jianhua Xu, Yuhan Shi, Xiaojing Wang, Yueguang Liu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-16 (2021)
Abstract Conversion of astrocytes into neurons in vivo offers an alternative therapeutic approach for neuronal loss after injury or disease. However, not only the efficiency of the conversion of astrocytes into functional neurons by single Neurog2, b
Externí odkaz:
https://doaj.org/article/78db388ee70f49c9ad99132ff9bf6933
Autor:
Sanlan Li, Yuhan Shi, Xuan Yao, Xing Wang, Libing Shen, Zhiping Rao, Jiacheng Yuan, Yueguang Liu, Zhenning Zhou, Ziheng Zhang, Fei Liu, Su’e Han, Junlan Geng, Hui Yang, Leping Cheng
Publikováno v:
Cell Reports, Vol 28, Iss 3, Pp 682-697.e7 (2019)
Summary: Dysfunction of noradrenergic (NA) neurons is associated with a number of neuronal disorders. Diverse neuronal subtypes can be generated by direct reprogramming. However, it is still unknown how to convert non-neuronal cells into NA neurons.
Externí odkaz:
https://doaj.org/article/832f2aba3a844d8884f93cef0e8b2072
Autor:
Xiaofeng Huang, Wei Gu, Jiaoyue Zhang, Ying Lan, Jonathan L. Colarusso, Sanlan Li, Christoph Pertl, Jiaqi Lu, Hyunkee Kim, Jian Zhu, David T. Breault, Jean Sévigny, Qiao Zhou
Publikováno v:
Nature Cell Biology. 25:778-786
Autor:
Xiaofeng Huang, Wei Gu, Jiaoyue Zhang, Ying Lan, Jonathan L. Colarusso, Sanlan Li, Christoph Pertl, Jiaqi Lu, Hyunkee Kim, Jian Zhu, Jean Sévigny, Qiao Zhou
Gut stem cells are accessible by biopsy and propagate robustly in culture, offering an invaluable resource for autologous cell therapies. Insulin-producing cells can be induced in mouse gut, but it has not been possible to generate abundant and durab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdb6fc1c6729d1f95dc88f031bcf5951
https://doi.org/10.1101/2022.12.15.520488
https://doi.org/10.1101/2022.12.15.520488
Autor:
Dengyu Lu, Yuhan Shi, Xiaojing Wang, Yijie Zhang, Fei Liu, Li Sun, Fuliang Chen, Jianhua Xu, Liu Yueguang, Sanlan Li, Jiacheng Yuan, Zhiping Rao, Junlan Geng, Sue Han
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-16 (2021)
Cell Death & Disease
Cell Death & Disease
Conversion of astrocytes into neurons in vivo offers an alternative therapeutic approach for neuronal loss after injury or disease. However, not only the efficiency of the conversion of astrocytes into functional neurons by single Neurog2, but also t
Akademický článek
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Autor:
Zhen Liu, Haibo Zhou, Chen-Chen Zhang, Leping Cheng, Xiaowen Shen, Hui Yang, Xuan Yao, Zijian Huang, Junlai Liu, Qiang Sun, Qifang Wang, Sanlan Li, Yan Wang, Yanhong Nie, Yan Wu, Xing Wang, Wenqin Ying, Pengyu Huang, Linyu Shi, Xinde Hu, Yu Wei
Publikováno v:
Cell Research
Targeted integration of transgenes can be achieved by strategies based on homologous recombination (HR), microhomology-mediated end joining (MMEJ) or non-homologous end joining (NHEJ). The more generally used HR is inefficient for achieving gene inte
Autor:
Hua-Tai Xu, Mingzhe Liu, Zhaorong Chen, Yifeng Zhang, Haishan Yao, Yingsi Zhou, B. D. Wang, Jinlin Su, Yidi Sun, Linyu Shi, He Li, Qingquan Xiao, Cheng Tang, Haibo Zhou, Fei Liu, Sanlan Li, Wenyan Wu, Xinde Hu, Canbin Feng, Linhan Wang, Hui Yang, Changyang Zhou
Publikováno v:
Cell. 181(3)
Summary Conversion of glial cells into functional neurons represents a potential therapeutic approach for replenishing neuronal loss associated with neurodegenerative diseases and brain injury. Previous attempts in this area using expression of trans
Autor:
Ran Wang, Zhiping Rao, Sanlan Li, Sue Han, Yuhan Shi, Naihe Jing, Cheng Leping, Licun Mo, Jiacheng Yuan
Publikováno v:
Stem Cell Reports
Summary Direct neuronal reprogramming potentially provides valuable sources for cell-based therapies. Proneural gene Ascl1 converts astrocytes into induced neuronal (iN) cells efficiently both in vitro and in vivo. However, the underlying mechanisms