Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Sankha Pattanayak"'
Publikováno v:
Current Protocols. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::855a45383cbc7914a447bab7a6474009
https://doi.org/10.1002/cpz1.686
https://doi.org/10.1002/cpz1.686
Publikováno v:
ChemBioChem. 23
Caged morpholino oligonucleotides (cMOs) are synthetic tools that allow light-inducible gene silencing in live organisms. Previously reported cMOs have utilized hairpin, duplex, and cyclic structures, as well as caged nucleobases. While these antisen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34790820ddcc8cbb24714a839225e21c
https://doi.org/10.1002/cbic.202200374
https://doi.org/10.1002/cbic.202200374
Autor:
Jayanta Kundu, Atanu Ghosh, Ujjwal Ghosh, Arnab Das, Dhriti Nagar, Sankha Pattanayak, Aurnab Ghose, Surajit Sinha
Publikováno v:
The Journal of organic chemistry. 87(15)
Phosphorodiamidate morpholino oligonucleotides (PMOs) constitute 3 out of the 11 FDA-approved oligonucleotide-based drugs in the last 6 years. PMOs can effectively silence disease-causing genes and modify splicing. However, PMO synthesis has remained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1352f62ddc8c41fb8384ad0ed41419e8
https://pubmed.ncbi.nlm.nih.gov/35839125
https://pubmed.ncbi.nlm.nih.gov/35839125
Caged morpholino oligonucleotides (cMOs) are synthetic tools that allow light-inducible gene silencing in live organisms. Previously reported cMOs have utilized hairpin, duplex, and cyclic structures, as well as caged nucleobases. While these optoche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9713c31ac0d843d21bfa27663c7f38e8
https://doi.org/10.26434/chemrxiv-2022-z6shp
https://doi.org/10.26434/chemrxiv-2022-z6shp
Autor:
Bappaditya Nandi, Jhuma Bhadra, Harleen Khatra, Surajit Sinha, Pragya Paramita Khan, Sankha Pattanayak
Publikováno v:
ChemistrySelect. 2:5059-5067
Cationic guanidinium and phosphonium functionalized cytosine morpholino tetramer (G3) and trimer (P3) have been reported for the first time. They show efficient cellular uptake properties in full growth medium, quantified by fluorescence activated ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f199f7733d041130b265abe3617ede06
https://doi.org/10.1002/slct.201700238
https://doi.org/10.1002/slct.201700238
Publikováno v:
Methods in Molecular Biology ISBN: 9781493992157
Morpholino antisense oligonucleotides are used as routine tools in developmental biology to investigate gene function during early embryogenesis. These chemically modified oligos contain morpholine ring connected with phosphorodiamidate linkages as b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7021d787c58182aafafe5fc67cd9332
https://doi.org/10.1007/978-1-4939-9216-4_7
https://doi.org/10.1007/978-1-4939-9216-4_7
Caged morpholino oligonucleotides (cMOs) are useful research tools in developmental biology because they allow spatiotemporal control of gene expression in whole organisms. While cMOs are usually triggered by light of a single wavelength, the introdu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351ca61ac7259588418fb52a094c393a
https://europepmc.org/articles/PMC7032742/
https://europepmc.org/articles/PMC7032742/
Autor:
Matthew K. McBride, Sudheendran Mavila, Dylan W. Domaille, Brady T. Worrell, Charles B. Musgrave, Chern-Hooi Lim, Christopher N. Bowman, Trevor M. Goldman, Heidi R. Culver, Chen Wang, Sankha Pattanayak
Publikováno v:
Journal of the American Chemical Society. 140(42)
The synthesis of thiolactone monomers that mimic natural nucleosides and engage in robust ring opening polymerizations (ROP) is herein described. As each repeat unit contains a thioester functional group, dynamic rearrangement of the polymer is feasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92178605d4e8066289f46cdcfe9eb5b2
https://pubmed.ncbi.nlm.nih.gov/30351134
https://pubmed.ncbi.nlm.nih.gov/30351134
Publikováno v:
RSC Adv.. 4:1951-1954
A guanidinium-linked morpholino pentamer is synthesized and evaluated for cellular penetration properties. A regular morpholino and the pentamer conjugate can exhibit antisense effects when designed against Gli1-transcription factors of the Hh signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efa6b4d5dd244a0c953f3018fc7d6d5b
https://doi.org/10.1039/c3ra45257c
https://doi.org/10.1039/c3ra45257c
Publikováno v:
Tetrahedron Letters. 55:1072-1076
Synthesis and cell transfection properties of guanidinium-functionalized uracil morpholino tetramer have been reported for the first time. Due to the basic nature of guanidinium groups they remain protonated under physiological conditions. Such catio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e667752104dcd85ecee1617076924c2
https://doi.org/10.1016/j.tetlet.2013.12.087
https://doi.org/10.1016/j.tetlet.2013.12.087