Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sankaranarayanan Rishikesan"'
Autor:
Malcolm S. Cole, Wassihun Wedajo Aragaw, Pooja Hegde, Malathy Sony Subramanian Manimekalai, Gerhard Grüber, Sankaranarayanan Rishikesan, Courtney C. Aldrich, Thomas Dick, Chitra Latka, Joon Shin, Priya Ragunathan
Publikováno v:
ACS Chem Biol
A common strategy employed in antibacterial drug discovery is targeting of biosynthetic processes which are essential and specific for the pathogen. Specificity in particular avoids undesirable interactions with potential enzymatic counterparts in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b173510492b1b0653a33e24175a77660
https://europepmc.org/articles/PMC8217388/
https://europepmc.org/articles/PMC8217388/
Autor:
Sankaranarayanan Rishikesan
Subunit G of the yeast V-ATPase is observed to be an elongated protein with a maximum size and the radius of gyration as 8.0 nm and 2.7 nm, respectively (ARMBRÜSTER et al., 2003). In order to understand the structure of subunit G and its possible or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6991bc33c472fa1db3800e80629b73
https://doi.org/10.32657/10356/47582
https://doi.org/10.32657/10356/47582
Publikováno v:
Røn, T, Sankaranarayanan, R, Chronakis, I S & Lee, S 2016, ' Slippery when sticky: Lubricating properties of thin films of Taxus baccata aril mucilage ', Biointerphases, vol. 11, no. 1, 011010 . https://doi.org/10.1116/1.4942208
Mucilage is hydrogel produced from succulent plants and microorganisms displaying unique adhesiveness and slipperiness simultaneously. The objective of this study is to establish an understanding on the lubricating mechanisms of the mucilage from Tax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2891bfe5923051afe4b9df3123b93cf
https://orbit.dtu.dk/en/publications/b60d8422-dbc4-4e2f-9d53-1eb1e587140b
https://orbit.dtu.dk/en/publications/b60d8422-dbc4-4e2f-9d53-1eb1e587140b
Publikováno v:
Journal of Bioenergetics and Biomembranes. 43:447-455
Subunit E of the vacuolar ATPase (V-ATPase) contains an N-terminal extended α helix (Rishikesan et al. J Bioenerg Biomembr 43:187-193, 2011) and a globular C-terminal part that is predicted to consist of a mixture of α-helices and β-sheets (Gruber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ee258a7b86a31316599a7d89659661c
https://doi.org/10.1007/s10863-011-9379-y
https://doi.org/10.1007/s10863-011-9379-y
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1798:1961-1968
Subunit G is an essential stalk subunit of the eukaryotic proton pump V(1)V(O) ATPase. Previously the structure of the N-terminal region, G(1)(-)(59), of the 13kDa subunit G was solved at higher resolution. Here solution NMR was performed to determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dddb927ed4f64ef7e068bc94e7bd598
https://doi.org/10.1016/j.bbamem.2010.06.012
https://doi.org/10.1016/j.bbamem.2010.06.012
Autor:
Navin J. Patil, Seunghwan Lee, Bruno Zappone, Ioannis S. Chronakis, Sankaranarayanan Rishikesan, Fatemeh Ajalloueian, Troels Røn
Publikováno v:
Røn, T, Patil, N J, Ajalloueian, F, Sankaranarayanan, R, Zappone, B, Chronakis, I S & Lee, S 2017, ' Gastric mucus and mucuslike hydrogels: Thin film lubricating properties at soft interfaces ', Biointerphases, vol. 12, no. 5, 051001 . https://doi.org/10.1116/1.5003708
Mucus is a viscous slime that plays a vital role in protecting and lubricating biological tissues, in particular, soft epithelium interfaces such as in the stomach, intestines, and esophagus. Previous attempts to generate mucus models that mimick or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a357d20e336d9d61628899c91106527
https://doi.org/10.1116/1.5003708
https://doi.org/10.1116/1.5003708
Autor:
Sankaranarayanan Rishikesan, Malathy Sony Subramanian Manimekalai, Yin Hoe Yau, Susana Geifman Shochat, Subramanian Vivekanandan, Shovanlal Gayen, Gerhard Grüber, Youg Raj Thaker
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1787:242-251
Understanding the structural traits of subunit G is essential, as it is needed for V(1)V(O) assembly and function. Here solution NMR of the recombinant N- (G(1-59)) and C-terminal segment (G(61-114)) of subunit G, has been performed in the absence an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee800cd457b1dabfffaee3b2cbb1e2a
https://doi.org/10.1016/j.bbabio.2009.01.010
https://doi.org/10.1016/j.bbabio.2009.01.010
Autor:
Ragunathan Priya, Gerhard Grüber, Youg Raj Thaker, Malathy Sony Subramanian Manimekalai, Sankaranarayanan Rishikesan, Shovanlal Gayen, Cornelia Hunke
Publikováno v:
Molecular Membrane Biology. 25:400-410
A critical point in the V(1) sector and entire V(1)V(O) complex is the interaction of stalk subunits G (Vma10p) and E (Vma4p). Previous work, using precipitation assays, has shown that both subunits form a complex. In this work, we have analysed the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88fc478c6e2af62a3df3ecb6bff4e7bb
https://doi.org/10.1080/09687680802183434
https://doi.org/10.1080/09687680802183434
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1777
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a34ddde91e78f1577002e0583d3cf92