Trichostatin a restores expression of adherens and tight junction proteins during transforming growth factor β-mediated epithelial-to-mesenchymal transition

Autor: Darshini A Ganatra, Abhay R Vasavada, Nair G Vidya, Devarshi U Gajjar, Sankaranarayanan Rajkumar

Publikováno v: Journal of Ophthalmic & Vision Research, Vol 13, Iss 3, Pp 274-283 (2018)

Purpose: Adherens junctions and polarity markers play an important role in maintaining epithelial phenotype but get altered during the epithelial-mesenchymal transition (EMT). Alterations of these markers during EMT of lens epithelial cell (LEC) can

Externí odkaz: https://doaj.org/article/cd35b90cda48462dade27a0acb1678fd

Long-term outcome of surgical excision of leukoplakia in a screening intervention trial, Kerala, India

Autor: Gigi Thomas, Ramadas Kunnambath, Thara Somanathan, Babu Mathew, Manoj Pandey, Sankaranarayanan Rangaswamy

Publikováno v: Journal of Indian Academy of Oral Medicine and Radiology, Vol 24, Iss 2, Pp 126-129 (2012)

Oral cancer is often preceeded by precancerous lesions and conditions, such as leukoplakia, erythroplakia and oral submucous fibrosis. One of the approaches for control of oral cancer is to detect oral precancerous lesions early in the development an

Externí odkaz: https://doaj.org/article/142f1a88581d4adf8e7921ebb002fd22

Prostate-Specific Membrane Antigen Targeted StarPEG Nanocarrier for Imaging and Therapy of Prostate Cancer.

Autor: Meher N; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA.; National Institute of Pharmaceutical Education and Research, Raebareli, Lucknow, UP, 226002, India., Ashley GW; ProLynx Inc., San Francisco, CA, 94158, USA., Bobba KN; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA., Wadhwa A; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA., Bidkar AP; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA., Dasari C; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, 94143-0981, USA., Mu C; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA., Sankaranarayanan RA; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA., Serrano JAC; Division of Vascular and Endovascular Surgery, University of California, San Francisco, CA, 94143-0957, USA., Raveendran A; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA., Bulkley DP; Department of Pathology, University of California, San Francisco, CA, 94143, USA., Aggarwal R; Division of Vascular and Endovascular Surgery, University of California, San Francisco, CA, 94143-0957, USA., Greenland NY; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, 94158-2517, USA., Oskowitz A; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, 94143-0981, USA., Wilson DM; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA.; Division of Vascular and Endovascular Surgery, University of California, San Francisco, CA, 94143-0957, USA., Seo Y; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA.; Division of Vascular and Endovascular Surgery, University of California, San Francisco, CA, 94143-0957, USA., Santi DV; ProLynx Inc., San Francisco, CA, 94158, USA., VanBrocklin HF; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA.; Division of Vascular and Endovascular Surgery, University of California, San Francisco, CA, 94143-0957, USA., Flavell RR; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA.; Division of Vascular and Endovascular Surgery, University of California, San Francisco, CA, 94143-0957, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA, 94158, USA.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2024 Jul; Vol. 13 (19), pp. e2304618. Date of Electronic Publication: 2024 May 17.

Simple plant-based production and purification of the assembled human ferritin heavy chain as a nanocarrier for tumor-targeted drug delivery and bioimaging in cancer therapy.

Autor: Knödler M; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V., Aachen, Germany.; Institute for Molecular Biotechnology, RWTH Aachen University, Aachen, Germany., Opdensteinen P; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V., Aachen, Germany.; Institute for Molecular Biotechnology, RWTH Aachen University, Aachen, Germany., Sankaranarayanan RA; Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, Aachen, Germany., Morgenroth A; Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, Aachen, Germany., Buhl EM; Electron Microscopy Facility, Institute for Pathology, University Hospital Aachen, RWTH Aachen University, Aachen, Germany., Mottaghy FM; Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands., Buyel JF; Institute for Molecular Biotechnology, RWTH Aachen University, Aachen, Germany.; Department of Biotechnology (DBT), Institute of Bioprocess Science and Engineering (IBSE), University of Natural Resources and Life Sciences, Vienna (BOKU), Vienna, Austria.

Publikováno v: Biotechnology and bioengineering [Biotechnol Bioeng] 2023 Apr; Vol. 120 (4), pp. 1038-1054. Date of Electronic Publication: 2023 Jan 02.

Auger Emitter Conjugated PARP Inhibitor for Therapy in Triple Negative Breast Cancers: A Comparative In-Vitro Study.

Autor: Sankaranarayanan RA; Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, 52074 Aachen, Germany., Peil J; Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, 52074 Aachen, Germany., Vogg ATJ; Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, 52074 Aachen, Germany., Bolm C; Institute of Organic Chemistry, RWTH Aachen University, 52056 Aachen, Germany., Terhorst S; Institute of Organic Chemistry, RWTH Aachen University, 52056 Aachen, Germany., Classen A; Institute of Organic Chemistry, RWTH Aachen University, 52056 Aachen, Germany., Bauwens M; Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, 52074 Aachen, Germany.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Center (MUMC+), 6229HX Maastricht, The Netherlands.; School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, 6229HX Maastricht, The Netherlands., Maurer J; Department of Molecular Gynecology, University Hospital Aachen, RWTH Aachen University, 52074 Aachen, Germany., Mottaghy F; Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, 52074 Aachen, Germany.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Center (MUMC+), 6229HX Maastricht, The Netherlands., Morgenroth A; Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, 52074 Aachen, Germany.

Publikováno v: Cancers [Cancers (Basel)] 2022 Jan 04; Vol. 14 (1). Date of Electronic Publication: 2022 Jan 04.