Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Sankaran Thayumanavan"'
Autor:
Ankita Mitra, Sudarvili Shanthalingam, Heather L. Sherman, Khushboo Singh, Mine Canakci, Joe A. Torres, Rebecca Lawlor, Yong Ran, Todd E. Golde, Lucio Miele, Sankaran Thayumanavan, Lisa M. Minter, Barbara A. Osborne
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Notch signaling provides an important cue in the mammalian developmental process. It is a key player in T cell development and function. Notch ligands such as Delta-like ligands (DLL) 1, 3, 4, and JAG1, 2 can impact Notch signaling positively or nega
Externí odkaz:
https://doaj.org/article/b79738f2155f436f935ff7314cefedd2
Autor:
Giovanni M. Pavan, Davide Bochicchio, Chiara Lionello, Manisha Shivrayan, Annalisa Cardellini, Andrea Gardin, Sankaran Thayumanavan, Ann Fernandez
Publikováno v:
ACS Nano
Nature designs chemotactic supramolecular structures that can selectively bind specific groups present on surfaces, autonomously scan them moving along density gradients, and react once a critical concentration is encountered. While such properties a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911235a63ea233be6a048aa42bfb075b
https://doi.org/10.1021/acsnano.1c05000
https://doi.org/10.1021/acsnano.1c05000
Exogenous Introduction of Initiator and Executioner Caspases Results in Different Apoptotic Outcomes
Publikováno v:
JACS Au, Vol 1, Iss 8, Pp 1240-1256 (2021)
JACS Au
JACS Au
The balance of pro-apoptotic and pro-survival proteins defines a cell's fate. These processes are controlled through an interdependent and finely tuned protein network that enables survival or leads to apoptotic cell death. The caspase family of prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fcc15a4ac017941b9130e8b91ae6bb4
https://doaj.org/article/72d8e511927844128801c27706b55122
https://doaj.org/article/72d8e511927844128801c27706b55122
Autor:
Jiaming Zhuang, Partha Sarathi Addy, Morgan M. Cencer, Jeffrey S. Moore, Manisha Shivrayan, Sankaran Thayumanavan
Publikováno v:
ACS macro letters. 9(6)
Interest in triggered depolymerization is growing, driven by needs in sustainable plastics, self-healing materials, controlled release, and sensory amplification. For many triggered depolymerization reactions, the rate-limiting step does not directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf314655c6b7b6673f3afa6858717d42
https://pubmed.ncbi.nlm.nih.gov/35648518
https://pubmed.ncbi.nlm.nih.gov/35648518
Publikováno v:
Angew Chem Int Ed Engl
We report here on protein-antibody conjugates (PACs) that are used for antibody-directed delivery of protein therapeutics to specific cells. PACs have the potential to judiciously combine the merits of two prolific therapeutic approaches, viz. biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a6b3c4545e08cbf414a581c1377b73
https://doi.org/10.1002/ange.202103106
https://doi.org/10.1002/ange.202103106
Autor:
Vincent M. Rotello, Shuting Pan, Jonathan P. Lee, Sankaran Thayumanavan, Sanjana Gopalakrishnan, Ann Fernandez, Li-Sheng Wang, Xuexin Duan, Yang Bai
Publikováno v:
Langmuir. 37:2826-2832
Hydrodynamic approaches are important for biomedical diagnostics, chemical analysis, and a broad range of industrial applications. Size-based separation and sorting is an important tool for these applications. We report the integration of hypersound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a42f79be127b112544b62920f1489c
https://doi.org/10.1021/acs.langmuir.0c03598
https://doi.org/10.1021/acs.langmuir.0c03598
Publikováno v:
Biochemistry
Self-assembled nanostructures that are sensitive to environmental stimuli are promising nanomaterials for drug delivery. In this class, disulfide-containing redox-sensitive strategies have gained enormous attention because of their wide applicability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3d83590c8e11c362618859c70a92cb
https://doi.org/10.1021/acs.biochem.0c00860
https://doi.org/10.1021/acs.biochem.0c00860
Publikováno v:
Chem Commun (Camb)
A protein binding-induced supramolecular dissociation strategy is developed with the ratio of monomer and excimer fluorescence as the tool for protein sensing and quantification. Due to the “lock-and-key” strategy based on specific ligand-protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234bc010e6293985c71c49dbca2101c5
https://doi.org/10.1039/d1cc03944j
https://doi.org/10.1039/d1cc03944j
Publikováno v:
Chem Commun (Camb)
Protein sensing strategies have implications in detection of many human pathologies. Here, a supramolecular strategy for sensing two different proteins using a multichannel readout approach is outlined. Protein-ligand binding or enzymatic cleavage ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deed3443262197e7132db92f4a480114
https://doi.org/10.1039/d1cc05407d
https://doi.org/10.1039/d1cc05407d