Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Sankaran, Sandhya"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
RNA is the key player in many cellular processes such as signal transduction, replication, transport, cell division, transcription, and translation. These diverse functions are accomplished through interactions of RNA with proteins. However, protein
Externí odkaz:
https://doaj.org/article/1d6c4dcb84e44e3a9eeb6cfd2f84a145
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Afrotheria is a clade of African-origin species with striking dissimilarities in appearance and habitat. In this study, we compared whole proteome sequences of six Afrotherian species to obtain a broad viewpoint of their underlying molecular
Externí odkaz:
https://doaj.org/article/2904cf922bb74c03b193316327334d40
Publikováno v:
Current Research in Structural Biology, Vol 3, Iss , Pp 133-145 (2021)
The evolution of homologous and functionally equivalent multiprotein assemblies is intriguing considering sequence divergence of constituent proteins. Here, we studied the implications of protein sequence divergence on the structure, dynamics and fun
Externí odkaz:
https://doaj.org/article/6507c4c62a4944f7a4e819baf5a21693
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Multi-protein assemblies are complex molecular systems that perform highly sophisticated biochemical functions in an orchestrated manner. They are subject to changes that are governed by the evolution of individual components. We performed a comparat
Externí odkaz:
https://doaj.org/article/e07ddf7aaba24bb3be02337a9d2bc759
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Ribosomes play a critical role in maintaining cellular proteostasis. The binding of messenger RNA (mRNA) to the ribosome regulates kinetics of protein synthesis. To generate an understanding of the structural, mechanistic, and dynamical features of m
Externí odkaz:
https://doaj.org/article/0b5cca2695f548dd8ee8795816bdbdb0
Publikováno v:
Biology Direct, Vol 13, Iss 1, Pp 1-13 (2018)
Abstract Background Knowledge of the protein structure is a pre-requisite for improved understanding of molecular function. The gap in the sequence-structure space has increased in the post-genomic era. Grouping related protein sequences into familie
Externí odkaz:
https://doaj.org/article/15b5a0de510e4da6bd8c72e125f7b9d8
Autor:
Firosh Khan, Abdulkhader Shehna, Sivaramakrishnan Ramesh, Kakkassery Sankaran Sandhya, Reji Paul
Publikováno v:
Annals of Indian Academy of Neurology, Vol 20, Iss 1, Pp 69-72 (2017)
Aim: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy and is one of the most common requests for electrodiagnosis. We aimed to note the relationship of subjective symptom severity of CTS, with objective electrophysiological sever
Externí odkaz:
https://doaj.org/article/2708cad2326243a2900facd26640f647
Autor:
Ramanathan Sowdhamini, Vasam Prabantu, Himani Tandon, Sankaran Sandhya, Narayanaswamy Srinivasan
Proteins such as enzymes perform their function by predominant non-covalent bond interactions between transiently interacting units. There is an impact on the overall structural topology of the protein, albeit transient nature of such interactions, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b18de1785f0417f997961dceac6cea7f
https://doi.org/10.22541/au.168553112.28170537/v1
https://doi.org/10.22541/au.168553112.28170537/v1
Publikováno v:
Toxins, Vol 12, Iss 8, p 481 (2020)
Mycobacterium tuberculosis genome encodes over 80 toxin–antitoxin (TA) systems. While each toxin interacts with its cognate antitoxin, the abundance of TA systems presents an opportunity for potential non-cognate interactions. TA systems mediate ma
Externí odkaz:
https://doaj.org/article/30c73992b87b47dfaeee23c46cbf4ac3
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205267 (2018)
BAF250a and BAF250b are subunits of the SWI/SNF chromatin-remodeling complex that recruit the complex to chromatin allowing transcriptional activation of several genes. Despite being the central subunits of the SWI/SNF complex, the structural and fun
Externí odkaz:
https://doaj.org/article/be9ca232a0844be89187b2b269b9c9cc