Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sankara, Sivaprasad"'
Autor:
Susheel J. Nara, Srinivas Jogi, Srinivas Cheruku, Sarkunam Kandhasamy, Firoz Jaipuri, Pavan Kalyan Kathi, Subba Reddy, Sanket Sarodaya, Erica M. Cook, Tao Wang, Doree Sitkoff, Karen A. Rossi, Max Ruzanov, Susan E. Kiefer, Javed A. Khan, Mian Gao, Satyanarayana Reddy, Sankara Sivaprasad LVJ, Ramola Sane, Kathy Mosure, Xiaoliang Zhuo, Gary G. Cao, Milinda Ziegler, Anthony Azzara, John Krupinski, Matthew G. Soars, Bruce A. Ellsworth, Dean A. Wacker
Publikováno v:
Journal of medicinal chemistry. 65(13)
While several farnesoid X receptor (FXR) agonists under clinical investigation for the treatment of nonalcoholic steatohepatitis (NASH) have shown beneficial effects, adverse effects such as pruritus and elevation of plasma lipids have limited their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950a84b56e656ee81f551db19a874f2a
https://pubmed.ncbi.nlm.nih.gov/35704802
https://pubmed.ncbi.nlm.nih.gov/35704802
Autor:
L.V.J. Sankara Sivaprasad, Bokka Venkata Murali, T. Thanga Mariappan, Sushma Basavanthappa, Avinash Annasao Hadambar, Vijaykumar Kuchibhotla, Avisek Deyati, Bradley A. Zinker, Gowtham Raj Gunti, Manjunath Ramarao, Sagnik Chatterjee, Shashyendra Singh Gautam, Yueping Zhang, Tanvi Naik, Hong Shen, Sambuddho Mukherjee, Michael Sinz
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 376:29-39
Expression and functional changes in the organic anion transporting polypeptide (OATP)-multidrug resistance-associated protein (MRP) axis of transporters are well reported in patients with nonalcoholic steatohepatitis (NASH). These changes can impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c586217f3e68fc4669c5919c8c6bfed3
https://doi.org/10.1124/jpet.120.000291
https://doi.org/10.1124/jpet.120.000291
Autor:
Nilesh Gaud, Tarun Sharma, Punit Marathe, Sheelendra Pratap Singh, Sundeep Paruchury, Sandhya Mandlekar, Rambabu Arla, Murali Subramanian, Vinay K. Holenarsipur, Priyadeep Bhutani, Sankara Sivaprasad, Jaydeep Sinha
Publikováno v:
Biopharmaceutics & Drug Disposition. 36:385-397
In recent years prodrug strategy has been used extensively to improve the pharmacokinetic properties of compounds exhibiting poor bioavailability. Mechanistic understanding of the absorption and the role of intestine and liver in the activation of or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::401d16c45f093a8780ed7da6e0f53970
https://doi.org/10.1002/bdd.1950
https://doi.org/10.1002/bdd.1950
Akademický článek
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Autor:
Vinay K, Holenarsipur, Nilesh, Gaud, Jaydeep, Sinha, Sankara, Sivaprasad, Priyadeep, Bhutani, Murali, Subramanian, Sheelendra Pratap, Singh, Rambabu, Arla, Sundeep, Paruchury, Tarun, Sharma, Punit, Marathe, Sandhya, Mandlekar
Publikováno v:
Biopharmaceuticsdrug disposition. 36(6)
In recent years prodrug strategy has been used extensively to improve the pharmacokinetic properties of compounds exhibiting poor bioavailability. Mechanistic understanding of the absorption and the role of intestine and liver in the activation of or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee324df7f66f4693a7782827b0e6679c
https://pubmed.ncbi.nlm.nih.gov/25832562
https://pubmed.ncbi.nlm.nih.gov/25832562