Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Sankar Mohan"'
Autor:
Zora Modrusan, Jerry Tang, Ajay Pandita, Sankar Mohan, Celina Sanchez Rivers, Robert Soriano, Yinghui Guan, Li Li, Eva Lin
The echinoderm microtubule-associated protein-like 4–anaplastic lymphoma kinase (EML4-ALK) fusion gene has been identified as an oncogene in a subset of non–small cell lung cancers (NSCLC). We used profiling of cancer genomes on an exon array to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e435e05633d673cded2e40ffc06d2a
https://doi.org/10.1158/1541-7786.c.6542118.v1
https://doi.org/10.1158/1541-7786.c.6542118.v1
Autor:
Guy Cavet, David Stokoe, John Chant, Levi A. Garraway, Paul Waring, Howard M. Stern, Somasekar Seshagiri, Zora Modrusan, Thinh Pham, William M. Lin, Steve Guerrero, Peng Yue, Sankar Mohan, Eva Lin, Ajay Pandita, Lin Ge, Barmak Modrek
Supplementary Data from Oncogenic Activating Mutations Are Associated with Local Copy Gain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2636ccc9d676c2228655d75c4591e990
https://doi.org/10.1158/1541-7786.22518897
https://doi.org/10.1158/1541-7786.22518897
Autor:
Guy Cavet, David Stokoe, John Chant, Levi A. Garraway, Paul Waring, Howard M. Stern, Somasekar Seshagiri, Zora Modrusan, Thinh Pham, William M. Lin, Steve Guerrero, Peng Yue, Sankar Mohan, Eva Lin, Ajay Pandita, Lin Ge, Barmak Modrek
Although activating mutations and gains in copy number are key mechanisms for oncogene activation, the relationship between the two is not well understood. In this study, we focused on KRAS copy gains and mutations in non–small cell lung cancer. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083ea643665429b21da4bc48096c95c1
https://doi.org/10.1158/1541-7786.c.6542172
https://doi.org/10.1158/1541-7786.c.6542172
Autor:
Zora Modrusan, Jerry Tang, Ajay Pandita, Sankar Mohan, Celina Sanchez Rivers, Robert Soriano, Yinghui Guan, Li Li, Eva Lin
Supplementary Data from Exon Array Profiling Detects EML4-ALK Fusion in Breast, Colorectal, and Non–Small Cell Lung Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e5ed44dab73e9f5e96fdd05b12bb30
https://doi.org/10.1158/1541-7786.22518801.v1
https://doi.org/10.1158/1541-7786.22518801.v1
Autor:
Mark R. Lackner, David S. Shames, Lukas C. Amler, Garret M. Hampton, Leanne Ross, Lori S. Friedman, Deepak Sampath, Sankar Mohan, Ajay Pandita, Peter M. Haverty, Rainer K. Brachmann, Jane Fridlyand, Hartmut Koeppen, Ling Huw, Carol O'Brien, Jill M. Spoerke
Purpose: Class 1 phosphatidylinositol 3-kinase (PI3K) plays a major role in cell proliferation and survival in a wide variety of human cancers. Here, we investigated biomarker strategies for PI3K pathway inhibitors in non–small-cell lung cancer (NS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb9f1ef4c3426577829c8470390f8ee
https://doi.org/10.1158/1078-0432.c.6522099
https://doi.org/10.1158/1078-0432.c.6522099
Autor:
Robert L. Yauch, Amy Peterson, Premal Patel, See-Chun Phan, Lukas Amler, Vanitha Ramakrishnan, Mirella Lazarov, Jenny Huang, Marina Lipkind, Ignacio Wistuba, David S. Shames, Ellen Filvaroff, Sharianne G. Louie, Tom Januario, Xiaoling Xia, Vaishali Parab, An Do, Ling Fu, Rupal Desai, Rajesh Patel, Sankar Mohan, Rajiv Raja, Linda Rangell, Elicia Penuel, Ajay Pandita, Jiping Zha, Wei Yu, Hartmut Koeppen
Figure S1. Characterization of SP44 specificity; Figure S2. Relationship of IHC intensity with FACS; Figure S3. Relationship of IHC intensity with mRNA; Figure S4. Representative IHC images; Figure S5 and S6. MET IHC H-scores; Figure S7. Relationship
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f30d3401a7f695ff0b6715b48881b37
https://doi.org/10.1158/1078-0432.22447172
https://doi.org/10.1158/1078-0432.22447172
Autor:
Mark R. Lackner, David S. Shames, Lukas C. Amler, Garret M. Hampton, Leanne Ross, Lori S. Friedman, Deepak Sampath, Sankar Mohan, Ajay Pandita, Peter M. Haverty, Rainer K. Brachmann, Jane Fridlyand, Hartmut Koeppen, Ling Huw, Carol O'Brien, Jill M. Spoerke
PDF file - 110K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd35abb90f0547628e08dea87f9b123
https://doi.org/10.1158/1078-0432.22451103.v1
https://doi.org/10.1158/1078-0432.22451103.v1
Autor:
Mark R. Lackner, David S. Shames, Lukas C. Amler, Garret M. Hampton, Leanne Ross, Lori S. Friedman, Deepak Sampath, Sankar Mohan, Ajay Pandita, Peter M. Haverty, Rainer K. Brachmann, Jane Fridlyand, Hartmut Koeppen, Ling Huw, Carol O'Brien, Jill M. Spoerke
XLSX file - 17K, PI3K pathway alterations in NSCLC cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9708b75c16b3d3da84a0342bf27834
https://doi.org/10.1158/1078-0432.22451097.v1
https://doi.org/10.1158/1078-0432.22451097.v1
Autor:
Robert L. Yauch, Amy Peterson, Premal Patel, See-Chun Phan, Lukas Amler, Vanitha Ramakrishnan, Mirella Lazarov, Jenny Huang, Marina Lipkind, Ignacio Wistuba, David S. Shames, Ellen Filvaroff, Sharianne G. Louie, Tom Januario, Xiaoling Xia, Vaishali Parab, An Do, Ling Fu, Rupal Desai, Rajesh Patel, Sankar Mohan, Rajiv Raja, Linda Rangell, Elicia Penuel, Ajay Pandita, Jiping Zha, Wei Yu, Hartmut Koeppen
Table S1. Overlap of biomarkers measured in OAM4558g; Table S2. Primer/probe information; Table S3. MET diagnostic scoring criteria; Table S4. MET IHC intratumoral heterogeneity; Table S5. Impact of KRAS/EGFR mutation on clinical outcome; Table S6. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc7e6eceddf0949632b7768ff664e20
https://doi.org/10.1158/1078-0432.22447166
https://doi.org/10.1158/1078-0432.22447166
Autor:
Mark R. Lackner, David S. Shames, Lukas C. Amler, Garret M. Hampton, Leanne Ross, Lori S. Friedman, Deepak Sampath, Sankar Mohan, Ajay Pandita, Peter M. Haverty, Rainer K. Brachmann, Jane Fridlyand, Hartmut Koeppen, Ling Huw, Carol O'Brien, Jill M. Spoerke
XLSX file - 18K, PI3K pathway alterations in NSCLC FFPE tumor samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ccae2bd3308c4df76e7c9e2d188d54
https://doi.org/10.1158/1078-0432.22451100.v1
https://doi.org/10.1158/1078-0432.22451100.v1