Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sankar Manepalli"'
Autor:
Emilio Xavier Esposito, Jason A. Berberich, Sankar Manepalli, Terry R. Stouch, Jeffry D. Madura
Publikováno v:
Chemical research in toxicology. 29(9)
There is a pressing need for new therapeutics to reactivate covalently inactivated acetylcholinesterase (AChE) due to exposure to organophosphorus (OP) compounds. Current reactivation therapeutics (RTs) are not broad-spectrum and suffer from other li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e8eee143999c3a2084ae9ffb36e39f
https://pubmed.ncbi.nlm.nih.gov/27494215
https://pubmed.ncbi.nlm.nih.gov/27494215
Autor:
Phillip N. Taylor, Tammy L. Nolan, David J. Lapinsky, Yi Liu, Jeffry D. Madura, Mary Ellen Amos, Jeffery N. Talbot, Christopher K. Surratt, Laura M. Geffert, Martín Indarte, Sankar Manepalli
Publikováno v:
ACS Chemical Neuroscience. 2:544-552
Ligand virtual screening (VS) using the vestibular binding pocket of a 3-D monoamine transporter (MAT) computational model followed by in vitro pharmacology led to the identification of a human serotonin transporter (hSERT) inhibitor with modest affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab52a6d6da13d77ef6d9affb7611222
https://doi.org/10.1021/cn200044x
https://doi.org/10.1021/cn200044x
Monoamine Transporter Structure, Function, Dynamics, and Drug Discovery: A Computational Perspective
With the breakthrough crystallization of the bacterial leucine transporter protein LeuT, the first available X-ray structure for the neurotransmitter/sodium symporter family, development of 3-D computational models is suddenly essential for structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556e38e108c2baea132f240ee99d8207
https://europepmc.org/articles/PMC3475841/
https://europepmc.org/articles/PMC3475841/
Autor:
Shaili Aggarwal, Christopher K. Surratt, David J. Lapinsky, Yi Liu, Yurong Huang, Martín Indarte, Sankar Manepalli, Jeffry D. Madura
Publikováno v:
The FASEB Journal. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1157b0762e1a869837cf490f479e53df
https://doi.org/10.1096/fasebj.23.1_supplement.746.2
https://doi.org/10.1096/fasebj.23.1_supplement.746.2