Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Sankar Basu"'
Autor:
Neethi C. Thathapudi, Natalia Callai-Silva, Kamal Malhotra, Sankar Basu, Mozhgan Aghajanzadeh-Kiyaseh, Mostafa Zamani-Roudbaraki, Marc Groleau, Félix Lombard-Vadnais, Sylvie Lesage, May Griffith
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Corneal HSV-1 infections are a leading cause of infectious blindness globally by triggering tissue damage due to the intense inflammation. HSV-1 infections are treated mainly with antiviral drugs that clear the infections but are inefficient
Externí odkaz:
https://doaj.org/article/6452d8bd7646481ea74da74285fad36f
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/d251288f53fa4a1fb14a07002f98d314
Autor:
Kamal Malhotra, Oleksiy Buznyk, Mohammad Mirazul Islam, Elle Edin, Sankar Basu, Marc Groleau, Delali Shana Dégué, Per Fagerholm, Adrien Fois, Sylvie Lesage, Jaganmohan R. Jangamreddy, Egidijus Šimoliūnas, Aneta Liszka, Hirak K. Patra, May Griffith
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1658 (2023)
Severe HSV-1 infection can cause blindness due to tissue damage from severe inflammation. Due to the high risk of graft failure in HSV-1-infected individuals, cornea transplantation to restore vision is often contraindicated. We tested the capacity f
Externí odkaz:
https://doaj.org/article/ead5572e2f674c328e776c27f4f02836
Publikováno v:
Frontiers in Bioinformatics, Vol 1 (2021)
Understanding the role of stability strengths and weaknesses in proteins is a key objective for rationalizing their dynamical and functional properties such as conformational changes, catalytic activity, and protein-protein and protein-ligand interac
Externí odkaz:
https://doaj.org/article/cc33f4ed640446bd910d23e1e1275813
Publikováno v:
Vaccines, Vol 10, Iss 2, p 301 (2022)
The COVID-19 origin debate has greatly been influenced by genome comparison studies of late, revealing the emergence of the Furin-like cleavage site at the S1/S2 junction of the SARS-CoV-2 Spike (FLCSSpike) containing its 681PRRAR685 motif, absent in
Externí odkaz:
https://doaj.org/article/e38e7a8650774637a3427b7942a63445
Autor:
Sankar Basu
Publikováno v:
Vaccines, Vol 9, Iss 10, p 1083 (2021)
As is well known, the emergence of SARS-CoV-2 ever since late 2019 [...]
Externí odkaz:
https://doaj.org/article/7f1600ead49c41d68949b413655c427a
Publikováno v:
Research, Vol 2018 (2018)
Nanoparticle bioreactivity critically depends upon interaction between proteins and nanomaterials (NM). The formation of the “protein corona” (PC) is the effect of such nanoprotein interactions. PC has a wide usage in pharmaceuticals, drug delive
Externí odkaz:
https://doaj.org/article/8a62075ba1b945f6b1971259ac16f13c
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 3, p 548 (2019)
Structural information of biological macromolecules is crucial and necessary to deliver predictions about the effects of mutations—whether polymorphic or deleterious (i.e., disease causing), wherein, thermodynamic parameters, namely, folding and bi
Externí odkaz:
https://doaj.org/article/b9005c06f76540ea9e23034fd0fd71b1
Autor:
Sankar Basu, Björn Wallner
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161879 (2016)
The state-of-the-art to assess the structural quality of docking models is currently based on three related yet independent quality measures: Fnat, LRMS, and iRMS as proposed and standardized by CAPRI. These quality measures quantify different aspect
Externí odkaz:
https://doaj.org/article/5dbba242796e4764b80b439f9489073c
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142173 (2015)
Currently, considerable interest exists with regard to the dissociation of close packed aminoacids within proteins, in the course of unfolding, which could result in either wet or dry moltenglobules. The progressive disjuncture of residues constituti
Externí odkaz:
https://doaj.org/article/e9e53e2821ad48a9a7081e9bcd858f67