Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Sanjoy Paul"'
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Iron acquisition is crucial for virulence of the human pathogen Aspergillus fumigatus. Previous studies indicated that this mold regulates iron uptake via both siderophores and reductive iron assimilation by the GATA factor SreA and the SREB
Externí odkaz:
https://doaj.org/article/9e5b026a813d4f77973d7d18337829b5
Autor:
Bijaya Basnet, Mojtaba Rajabi, Hao Wang, Priyanka Kumari, Kamal Thapa, Sanjoy Paul, Maxim O. Lavrentovich, Oleg D. Lavrentovich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Surface interactions are usually polar along the normal to the interface and apolar within the interface. Here, the authors find that polar in-plane surface interactions produce domain structures in the bulk of a ferroelectric nematic liquid crystal.
Externí odkaz:
https://doaj.org/article/d9dbc9c391974955b7a393e02caa2260
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract Background The prevailing medical opinion is that medication is the primary (some might argue, only) effective intervention for osteoporosis. It is nevertheless recognized that osteoporosis medications are not universally effective, tolerate
Externí odkaz:
https://doaj.org/article/e3aa6d452f944fa4a31b7f0d7a11168e
Publikováno v:
mSphere, Vol 7, Iss 6 (2022)
ABSTRACT Azole drugs represent the primary means of treating infections associated with the filamentous fungal pathogen Aspergillus fumigatus. A central player in azole resistance is the Zn2Cys6 zinc cluster-containing transcription factor AtrR. This
Externí odkaz:
https://doaj.org/article/c9e95c8220794f978ef4598b11003783
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Aspergillus fumigatus is the major filamentous fungal pathogen in humans. The gold standard treatment of A. fumigatus is based on azole drug use, but the appearance of azole-resistant isolates is increasing at an alarming rate. The cyp51A ge
Externí odkaz:
https://doaj.org/article/2d974d8e895d42f09e44597c56964cc3
Publikováno v:
AIP Advances, Vol 12, Iss 5, Pp 055314-055314-8 (2022)
We report the synthesis of wide-bandgap β-Ga2O3 nanocrystalline thin films via the low-cost and non-vacuum-based liquid phase deposition (LPD) method. The morphological evolution of the nanocrystalline β-Ga2O3 grains was investigated as a function
Externí odkaz:
https://doaj.org/article/723835aba49f41899bf77d72dc180e55
Publikováno v:
mSphere, Vol 7, Iss 1 (2022)
ABSTRACT The production of a collection of deletion mutant strains corresponding to a large number of transcription factors from the filamentous fungal pathogen Aspergillus fumigatus has permitted rapid identification of transcriptional regulators in
Externí odkaz:
https://doaj.org/article/84a7faa165914d3b96c4ab19f9af0304
Autor:
Takanori Furukawa, Norman van Rhijn, Marcin Fraczek, Fabio Gsaller, Emma Davies, Paul Carr, Sara Gago, Rachael Fortune-Grant, Sayema Rahman, Jane Mabey Gilsenan, Emma Houlder, Caitlin H. Kowalski, Shriya Raj, Sanjoy Paul, Peter Cook, Josie E. Parker, Steve Kelly, Robert A. Cramer, Jean-Paul Latgé, Scott Moye-Rowley, Elaine Bignell, Paul Bowyer, Michael J. Bromley
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Resistance to primary treatments of invasive aspergillosis is growing. Here, the authors generate a knockout library for 484 transcription factors in Aspergillus fumigatus, and show that loss of the NCT complex leads to cross-resistance to all primar
Externí odkaz:
https://doaj.org/article/5e2ad52f5b324f87841175e72f74a7dd
Autor:
Sanjoy Paul, Mark Stamnes, Grace Heredge Thomas, Hong Liu, Daisuke Hagiwara, Katsuya Gomi, Scott G. Filler, W. Scott Moye-Rowley
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Aspergillosis associated with azole-resistant Aspergillus fumigatus has a mortality rate that can approach 90% in certain patient populations. The best-understood avenue for azole resistance involves changes in the cyp51A gene that encodes t
Externí odkaz:
https://doaj.org/article/04ab0a88ea04405a8699079ec5d9d53e
Autor:
Daisuke Hagiwara, Daisuke Miura, Kiminori Shimizu, Sanjoy Paul, Ayumi Ohba, Tohru Gonoi, Akira Watanabe, Katsuhiko Kamei, Takahiro Shintani, W Scott Moye-Rowley, Susumu Kawamoto, Katsuya Gomi
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006096 (2017)
Successful treatment of aspergillosis caused by Aspergillus fumigatus is threatened by an increasing incidence of drug resistance. This situation is further complicated by the finding that strains resistant to azoles, the major antifungal drugs for a
Externí odkaz:
https://doaj.org/article/e942135674ca40288ad5fe2e79c06ea8