Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sanjivan Gautam"'
Autor:
Harpal Randeva, Derrick Bennett, Charlotte E Bolton, Paramjit Gill, Anders Løkke, Peter Phiri, Pramod R Regmi, Edwin van Teijlingen, Puspa Raj Pant, Kin Bong Hubert Lam, Padam Simkhada, Ioannis Kyrou, Gayathri Delanerolle, Ashish Shetty, John Balmes, Adnan Custovic, Vanora Hundley, Imran Satia, Nagendra Chaudhary, Tara Ballav Adhikari, Om P. Kurmi, Sanjivan Gautam, Prashil Raj Dali, Paul O'Byrne, Rajendra Pangeni, Milan Bimali, Dipak Uprety, Jian Shi Qing, Ashesh Dhungana, John Hurst, Balram Gautam, Jagat Jeevan Ghimire, Sudhir Kumar Tyagi, Satyendra Upadhyay, Tara Kanta Sigdel
Publikováno v:
BMJ Open, Vol 14, Iss 11 (2024)
Introduction The Nepal Family Cohort study uses a life course epidemiological approach to collect comprehensive data on children’s and their parents’ environmental, behavioural and metabolic risk factors. These factors can affect the overall deve
Externí odkaz:
https://doaj.org/article/cee0646bda9b4e738e9a3ee1728dbb60
Autor:
Yun Ji, Jessica Fioravanti, Wei Zhu, Hongjun Wang, Tuoqi Wu, Jinhui Hu, Neal E. Lacey, Sanjivan Gautam, John B. Le Gall, Xia Yang, James D. Hocker, Thelma M. Escobar, Shan He, Stefania Dell’Orso, Nga V. Hawk, Veena Kapoor, William G. Telford, Luciano Di Croce, Stefan A. Muljo, Yi Zhang, Vittorio Sartorelli, Luca Gattinoni
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
The inability of T cells to properly mount anti-tumour immunity underlies failed cancer immune surveillance or therapy. Here the authors show that a microRNA, miR-155, suppresses Ship1 phosphatase expression to modulate epigenetic reprogramming of CD
Externí odkaz:
https://doaj.org/article/f7106871939f484092d79cd389893db3
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168055 (2016)
Severe congenital neutropenia (SCN) is characterised by a differentiation block in the bone marrow and low neutrophil numbers in the peripheral blood, which correlates with increased risk of bacterial infections. Several underlying gene defects have
Externí odkaz:
https://doaj.org/article/4e082e5e17d449a39da0fb049bd184f2
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/ef68abd3dd4f4df792444dadfe595ad9
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79352 (2013)
Neutrophil granulocyte (neutrophil) apoptosis plays a key role in determining inflammation in infectious and non-infectious settings. Recent work has shown that inhibitors of cyclin-dependent kinases (cdk) such as roscovitine can potently induce neut
Externí odkaz:
https://doaj.org/article/4da23675a46847c3b4e5e0d32eb6d732
Autor:
Christopher K. E. Bleck, Peng Li, Rosanne Spolski, Leonard M. Neckers, Jian Xin Lin, Luca Gattinoni, Juan Carlos García-Cañaveras, Daniel Gromer, Ning Du, Stephen M. Christensen, Warren J. Leonard, Jessica Fioravanti, Suman Mitra, Joshua D. Rabinowitz, Rosa Nguyen, Jangsuk Oh, Sanjivan Gautam, Dalton Hermans, Risa Ebina-Shibuya, Sharon Veenbergen
Publikováno v:
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117, 6047-6055. National Academy of Sciences
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Proceedings of the National Academy of Sciences of the United States of America, 117, 6047-6055. National Academy of Sciences
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Interleukin (IL)-2 and IL-21 dichotomously shape CD8 + T cell differentiation. IL-2 drives terminal differentiation, generating cells that are poorly effective against tumors, whereas IL-21 promotes stem cell memory T cells (T SCM ) and antitumor res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffe31d96b13ac0493e570267d480d74
https://doi.org/10.1073/pnas.1920413117
https://doi.org/10.1073/pnas.1920413117
Autor:
Nicholas P. Restifo, Luca Gattinoni, Rahul Roychoudhuri, Timothy P. Bender, Avinash Bhandoola, Philip Brohawn, Veena Kapoor, Wei Zhu, John B. Le Gall, Sanjivan Gautam, Brandon W. Higgs, Devikala Gurusamy, Zhiya Yu, Yun Ji, James D. Hocker, Nga V. Hawk, Neal E. Lacey, Jessica Fioravanti, Jinhui Hu, William G. Telford, Hai-Hui Xue
Publikováno v:
Nature immunology
Stem cells are maintained by transcriptional programs that promote self-renewal and repress differentiation. Here, we found that the transcription factor c-Myb was essential for generating and maintaining stem cells in the CD8+ T cell memory compartm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd1b40ba524564154542aa3aaa268fe
http://europepmc.org/articles/PMC6489499
http://europepmc.org/articles/PMC6489499
Autor:
Dalton, Hermans, Sanjivan, Gautam, Juan C, García-Cañaveras, Daniel, Gromer, Suman, Mitra, Rosanne, Spolski, Peng, Li, Stephen, Christensen, Rosa, Nguyen, Jian-Xin, Lin, Jangsuk, Oh, Ning, Du, Sharon, Veenbergen, Jessica, Fioravanti, Risa, Ebina-Shibuya, Christopher, Bleck, Leonard M, Neckers, Joshua D, Rabinowitz, Luca, Gattinoni, Warren J, Leonard
Publikováno v:
Proc Natl Acad Sci U S A
Interleukin (IL)-2 and IL-21 dichotomously shape CD8(+) T cell differentiation. IL-2 drives terminal differentiation, generating cells that are poorly effective against tumors, whereas IL-21 promotes stem cell memory T cells (T(SCM)) and antitumor re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06f771a4b28a0f2dda5761c8ae84df63
https://pubmed.ncbi.nlm.nih.gov/32123114
https://pubmed.ncbi.nlm.nih.gov/32123114
Autor:
Haiying Qin, Christopher A. Klebanoff, Yun Ji, Marianna Sabatino, Michele Sommariva, Terry J. Fry, James D. Hocker, Jinhui Hu, David F. Stroncek, Luca Gattinoni, James N. Kochenderfer, Vicki Fellowes, Ronald E. Gress, Sean C. Dougherty, Sanjivan Gautam
Publikováno v:
Blood. 128:519-528
Long-lived, self-renewing, multipotent T memory stem cells (TSCM) can trigger profound and sustained tumor regression but their rareness poses a major hurdle to their clinical application. Presently, clinically compliant procedures to generate releva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e656433ebf09a4f21c27d20f413a01
https://doi.org/10.1182/blood-2015-11-683847
https://doi.org/10.1182/blood-2015-11-683847
Autor:
Gabriele De Simone, Sanjivan Gautam, Karolina Pilipow, Eloise Scamardella, Simone Puccio, Veronica Zanon, Federica De Paoli, Sara Polletti, Luca Gattinoni, Marta Buccilli, Enrico Lugli, Pietro Di Lucia, Emilia Maria Cristina Mazza, Matteo Iannacone
Adoptive T cell transfer (ACT) immunotherapy benefits from early differentiated stem cell memory T (Tscm) cells capable of persisting in the long term and generating potent antitumor effectors. Due to their paucity ex vivo, Tscm cells can be derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d495a6fed2abb8886453b96281160b
