Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Sanjiv V, Bhave"'
Publikováno v:
Gene. 491:224-231
As an activator of adenylate cyclase, the neuropeptide Pituitary Adenylate Cyclase Activating Peptide (PACAP) impacts levels of cyclic AMP, a key second messenger available in brain cells. PACAP is involved in certain adult behaviors. To elucidate PA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e6e7f5a9170cbb1281cfac00ac89f4
https://doi.org/10.1016/j.gene.2011.09.017
https://doi.org/10.1016/j.gene.2011.09.017
Autor:
Phyllis Carosone-Link, Cheryl K. Hornbaker, Robert W. Williams, Katerina Kechris, Laura Saba, Sanjiv V. Bhave, Boris Tabakoff, Paula L. Hoffman, Beth Bennett
Publikováno v:
Addiction Biology. 16:393-404
The identification of genes that contribute to polygenic (complex) behavioral phenotypes is a key goal of current genetic research. One approach to this goal is to combine gene expression information with genetic information, i.e., to map chromosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a1bffe8323de53d2b90409a3d375f19
https://doi.org/10.1111/j.1369-1600.2010.00254.x
https://doi.org/10.1111/j.1369-1600.2010.00254.x
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 326:792-800
Alcohol "sensitivity" has been proposed as a predictive factor for development of alcohol dependence (Schuckit et al., 2005). Most measures of alcohol sensitivity in humans and animals include a component that can be ascribed to acute functional tole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2447c9e65547dbd1184569f1394d50ab
https://doi.org/10.1124/jpet.108.137521
https://doi.org/10.1124/jpet.108.137521
Autor:
Boris Tabakoff, Katherina Kechris, Sanjiv V. Bhave, Wei Hu, Nicholas J. Grahame, Deborah A. Finn, Laura Saba, Paula L. Hoffman
Publikováno v:
Mammalian Genome. 19:352-365
Searches for the identity of genes that influence the levels of alcohol consumption by humans and other animals have often been driven by presupposition of the importance of particular gene products in determining positively or negatively reinforcing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7d8d00c28cada0f72b6a5c6e3df17c
https://doi.org/10.1007/s00335-008-9115-z
https://doi.org/10.1007/s00335-008-9115-z
Ascertaining an individual’s history of alcohol consumption is an important component in the proper treatment of accidental trauma or acute or chronic illness, as well as for matters of public health and safety, legal issues, insurance coverage, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bd129e26b9f5e9dcf696c42f855acf1
https://doi.org/10.1093/oxfordhb/9780199381708.013.23
https://doi.org/10.1093/oxfordhb/9780199381708.013.23
Gene Array Profiles of Alcohol and Aldehyde Metabolizing Enzymes in Brains of C57BL/6 and DBA/2 Mice
Autor:
Natalie Lassen, Sanjiv V. Bhave, Paula L. Hoffman, Laura Saba, Vasilis Vasiliou, Richard A. Deitrich, Boris Tabakoff
Publikováno v:
Alcoholism: Clinical and Experimental Research. 30:1659-1669
Background: Differences in ethanol metabolizing enzymes expressed in brain have been suggested to contribute to the significant differences in ethanol (alcohol) preference between inbred C57BL/6 and DBA/2 mouse strains. Methods: We have utilized 2 di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249d2739012866337a393ad0e4c01fd9
https://doi.org/10.1111/j.1530-0277.2006.00201.x
https://doi.org/10.1111/j.1530-0277.2006.00201.x
Autor:
Sanjiv V. Bhave, Paula L. Hoffman
Publikováno v:
Journal of Neurochemistry. 88:359-369
Cerebellar granule neurons cultured in the presence of 5 mm KCl undergo spontaneous apoptosis, which is reduced by exposure to pituitary adenylyl cyclase-activating polypeptide (PACAP). Previous work has suggested roles for the cyclic AMP/PKA and MAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc5dfbe4fb45c3d5f593e3919b07caa7
https://doi.org/10.1046/j.1471-4159.2003.02167.x
https://doi.org/10.1046/j.1471-4159.2003.02167.x
Publikováno v:
The Journal of Neuroscience. 23:4491-4498
Acute functional tolerance to ethanol develops during a single exposure to ethanol; it has been suggested to be a predisposing factor for the development of ethanol dependence. Genetic determinants of acute functional tolerance, as well as of ethanol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2324c94ee259d5aa113cc2e1dba7d4c6
https://doi.org/10.1523/jneurosci.23-11-04491.2003
https://doi.org/10.1523/jneurosci.23-11-04491.2003
Publikováno v:
Journal of Neurochemistry. 67:557-565
We demonstrate that 1-methyl-4-phenylpyridinium (MPP + ) is toxic to chick peripheral sympathetic neurons maintained in culture in the presence of nerve growth factor (NGF). When MPP + was added to the culture medium at the time the neurons were plat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45925da209acd516ad9ada8c1d411ff
https://doi.org/10.1046/j.1471-4159.1996.67020557.x
https://doi.org/10.1046/j.1471-4159.1996.67020557.x
Publikováno v:
Journal of Neurochemistry. 75:1035-1044
Ethanol, added to primary cultures of cerebellar granule neurons simultaneously with NMDA, was previously shown to inhibit the anti-apoptotic effect of NMDA. The in vitro anti-apoptotic effect of NMDA is believed to mimic in vivo protection against a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8865e9842635165a801d5adf7bf39b4
https://doi.org/10.1046/j.1471-4159.2000.0751035.x
https://doi.org/10.1046/j.1471-4159.2000.0751035.x