Zobrazeno 1 - 10
of 1 002
pro vyhledávání: '"Sanjiv S. Gambhir"'
Autor:
Quan Zhou, Johana C. M. Vega Leonel, Michelle Rai Santoso, Christy Wilson, Nynke S. van den Berg, Carmel T. Chan, Muna Aryal, Hannes Vogel, Romain Cayrol, Michael J. Mandella, Frank Schonig, Guolan Lu, Sanjiv S. Gambhir, Michael E. Moseley, Eben L. Rosenthal, Gerald A. Grant
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The prognosis for high-grade glioma (HGG) remains dismal and the extent of resection correlates with overall survival and progression free disease. Epidermal growth factor receptor (EGFR) is a biomarker heterogeneously expressed in HGG. We a
Externí odkaz:
https://doaj.org/article/221b0fd8becb4a9a9cf3556f71c46c2e
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 1, Pp 58-67 (2021)
Despite the anti-proliferative and survival benefits from tumor treating fields (TTFields) in human glioblastoma (hGBM), little is known about the effects of this form of alternating electric fields therapy on the aberrant glycolysis of hGBM. [18F]FD
Externí odkaz:
https://doaj.org/article/78fbf65abcd14fca8529674bee118405
Autor:
Sharon S. Hori, Ling Tong, Srividya Swaminathan, Mariola Liebersbach, Jingjing Wang, Sanjiv S. Gambhir, Dean W. Felsher
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The targeted inactivation of individual oncogenes can elicit regression of cancers through a phenomenon called oncogene addiction. Oncogene addiction is mediated by cell-autonomous and immune-dependent mechanisms. Therapeutic resistance to o
Externí odkaz:
https://doaj.org/article/5eaa4c551c6b436ebaa97bfaaabc2d0e
Autor:
Sonya Y. Park, Camila Mosci, Meena Kumar, Mirwais Wardak, Norman Koglin, Santiago Bullich, Andre Mueller, Mathias Berndt, Andrew W. Stephens, Frederick T. Chin, Sanjiv S. Gambhir, Erik S. Mittra
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Purpose (4S)-4-(3-[18F]Fluoropropyl)-l-glutamic acid ([18F]FSPG) measures system xC − transporter activity and shows promise for oncologic imaging. We present data on tumor uptake of this radiopharmaceutical in human subjects with head and
Externí odkaz:
https://doaj.org/article/97f3df152e174153b67cf1d6636b932f
Autor:
Kristine Arges, Themistocles Assimes, Vikram Bajaj, Suresh Balu, Mustafa R. Bashir, Laura Beskow, Rosalia Blanco, Robert Califf, Paul Campbell, Larry Carin, Victoria Christian, Scott Cousins, Millie Das, Marie Dockery, Pamela S. Douglas, Ashley Dunham, Julie Eckstrand, Dominik Fleischmann, Emily Ford, Elizabeth Fraulo, John French, Sanjiv S. Gambhir, Geoffrey S. Ginsburg, Robert C. Green, Francois Haddad, Adrian Hernandez, John Hernandez, Erich S. Huang, Glenn Jaffe, Daniel King, Lynne H. Koweek, Curtis Langlotz, Yaping J. Liao, Kenneth W. Mahaffey, Kelly Marcom, William J. Marks, David Maron, Reid McCabe, Shannon McCall, Rebecca McCue, Jessica Mega, David Miller, Lawrence H. Muhlbaier, Rajan Munshi, L. Kristin Newby, Ezra Pak-Harvey, Bray Patrick-Lake, Michael Pencina, Eric D. Peterson, Fatima Rodriguez, Scarlet Shore, Svati Shah, Steven Shipes, George Sledge, Susie Spielman, Ryan Spitler, Terry Schaack, Geeta Swamy, Martin J. Willemink, Charlene A. Wong
Publikováno v:
npj Digital Medicine, Vol 3, Iss 1, Pp 1-10 (2020)
Abstract The Project Baseline Health Study (PBHS) was launched to map human health through a comprehensive understanding of both the health of an individual and how it relates to the broader population. The study will contribute to the creation of a
Externí odkaz:
https://doaj.org/article/363af385f20a4bb6bc414ac3b1588ec6
Autor:
Amin Aalipour, Fabrice Le Boeuf, Matthew Tang, Surya Murty, Federico Simonetta, Alexander X. Lozano, Travis M. Shaffer, John C. Bell, Sanjiv S. Gambhir
Publikováno v:
Molecular Therapy: Oncolytics, Vol 17, Iss , Pp 232-240 (2020)
Chimeric antigen receptor (CAR) T cell therapy has had limited efficacy for solid tumors, largely due to a lack of selectively and highly expressed surface antigens. To avoid reliance on a tumor’s endogenous antigens, here we describe a method of t
Externí odkaz:
https://doaj.org/article/b88cd715de77445cb52c1e4d99ad852a
Autor:
Toshihito Hirai, Aaron T. Mayer, Tomomi W. Nobashi, Po-Yu Lin, Zunyu Xiao, Tomokatsu Udagawa, Kinya Seo, Federico Simonetta, Jeanette Baker, Alan G. Cheng, Robert S. Negrin, Sanjiv S. Gambhir
Publikováno v:
JCI Insight, Vol 6, Iss 13 (2021)
Diagnosis of organ transplant rejection relies upon biopsy approaches to confirm alloreactive T cell infiltration in the graft. Immune molecular monitoring is under investigation to screen for rejection, though these techniques have suffered from low
Externí odkaz:
https://doaj.org/article/c1f094bd3b0848fca8511d53754ea57d
Autor:
Richard H. Kimura, Ling Wang, Bin Shen, Li Huo, Willemieke Tummers, Fabian V. Filipp, Haiwei Henry Guo, Thomas Haywood, Lotfi Abou-Elkacem, Lucia Baratto, Frezghi Habte, Rammohan Devulapally, Timothy H. Witney, Yan Cheng, Suhas Tikole, Subhendu Chakraborti, Jay Nix, Christopher A. Bonagura, Negin Hatami, Joshua J. Mooney, Tushar Desai, Scott Turner, Richard S. Gaster, Andrea Otte, Brendan C. Visser, George A. Poultsides, Jeffrey Norton, Walter Park, Mark Stolowitz, Kenneth Lau, Eric Yang, Arutselvan Natarajan, Ohad Ilovich, Shyam Srinivas, Ananth Srinivasan, Ramasamy Paulmurugan, Juergen Willmann, Frederick T. Chin, Zhen Cheng, Andrei Iagaru, Fang Li, Sanjiv S. Gambhir
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Knottin is a cystine knot peptide. Here, the authors develop a knottin-based tracer for positron emission tomography and demonstrate its ability to detect cancer and idiopathic pulmonary fibrosis through selective binding to integrin αvβ6.
Externí odkaz:
https://doaj.org/article/029f63b5dea042f582dd348aecf36a8e
Autor:
Idan Steinberg, David M. Huland, Ophir Vermesh, Hadas E. Frostig, Willemieke S. Tummers, Sanjiv S. Gambhir
Publikováno v:
Photoacoustics, Vol 14, Iss , Pp 77-98 (2019)
Photoacoustic is an emerging biomedical imaging modality, which allows imaging optical absorbers in the tissue by acoustic detectors (light in - sound out). Such a technique has an immense potential for clinical translation since it allows high resol
Externí odkaz:
https://doaj.org/article/678cac7480284190a87ca5ad8db8cefc
Autor:
Ophir Vermesh, Fariah Mahzabeen, Jelena Levi, Marilyn Tan, Israt S. Alam, Carmel T. Chan, Sanjiv S. Gambhir, James S. Harris
Publikováno v:
MethodsX, Vol 8, Iss , Pp 101414- (2021)
A miniaturized optoelectronic sensor is demonstrated that measures total protein concentration in serum and urine with sensitivity and accuracy comparable to gold-standard methods. The sensor is comprised of a vertical cavity surface emitting laser (
Externí odkaz:
https://doaj.org/article/461560c9a35046d290ac9f225737d45e