Zobrazeno 1 - 10
of 1 002
pro vyhledávání: '"Sanjiv S Gambhir"'
Autor:
Aloma L D'Souza, John R Chevillet, Pejman Ghanouni, Xinrui Yan, Muneesh Tewari, Sanjiv S Gambhir
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194268 (2018)
We have previously shown that low frequency ultrasound can release biomarkers from cells into the murine circulation enabling an amplification and localization of the released biomarker that could be used as a blood-based method to detect cancer earl
Externí odkaz:
https://doaj.org/article/c6313db348ee4d46982e9291515105c9
Autor:
Chin Chun Ooi, Gary L Mantalas, Winston Koh, Norma F Neff, Teruaki Fuchigami, Dawson J Wong, Robert J Wilson, Seung-Min Park, Sanjiv S Gambhir, Stephen R Quake, Shan X Wang
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188510 (2017)
Single-cell characterization techniques, such as mRNA-seq, have been applied to a diverse range of applications in cancer biology, yielding great insight into mechanisms leading to therapy resistance and tumor clonality. While single-cell techniques
Externí odkaz:
https://doaj.org/article/6d5de9d2ecd34b6cbdab7cdcfad78c49
Autor:
Erik S Mittra, Norman Koglin, Camila Mosci, Meena Kumar, Aileen Hoehne, Khun Visith Keu, Andrei H Iagaru, Andre Mueller, Mathias Berndt, Santiago Bullich, Matthias Friebe, Heribert Schmitt-Willich, Volker Gekeler, Lüder M Fels, Claudia Bacher-Stier, Dae Hyuk Moon, Frederick T Chin, Andrew W Stephens, Ludger M Dinkelborg, Sanjiv S Gambhir
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148628 (2016)
PURPOSE:(S)-4-(3-[18F]Fluoropropyl)-L-glutamic acid (18F-FSPG) is a novel radiopharmaceutical for Positron Emission Tomography (PET) imaging. It is a glutamate analogue that can be used to measure xC- transporter activity. This study was performed to
Externí odkaz:
https://doaj.org/article/128f37791bfe45c89d22f4e1d5687787
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152597 (2016)
In this work, we compare the merits of three temporal data deconvolution methods for use in the filtered backprojection algorithm for photoacoustic tomography (PAT). We evaluate the standard Fourier division technique, the Wiener deconvolution filter
Externí odkaz:
https://doaj.org/article/31a1968c296842ec980c622d2a0e0e52
Autor:
Hermann B Frieboes, Bryan R Smith, Zhihui Wang, Masakatsu Kotsuma, Ken Ito, Armin Day, Benjamin Cahill, Colin Flinders, Shannon M Mumenthaler, Parag Mallick, Eman Simbawa, A S Al-Fhaid, S R Mahmoud, Sanjiv S Gambhir, Vittorio Cristini
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129433 (2015)
We combine mathematical modeling with experiments in living mice to quantify the relative roles of intrinsic cellular vs. tissue-scale physiological contributors to chemotherapy drug resistance, which are difficult to understand solely through experi
Externí odkaz:
https://doaj.org/article/e3487eba4853460f845a086b6083a380
Autor:
Ellis Garai, Steven Sensarn, Cristina L Zavaleta, Nathan O Loewke, Stephan Rogalla, Michael J Mandella, Stephen A Felt, Shai Friedland, Jonathan T C Liu, Sanjiv S Gambhir, Christopher H Contag
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123185 (2015)
The detection of biomarker-targeting surface-enhanced Raman scattering (SERS) nanoparticles (NPs) in the human gastrointestinal tract has the potential to improve early cancer detection; however, a clinically relevant device with rapid Raman-imaging
Externí odkaz:
https://doaj.org/article/d4c2dc985ab548b297c3e32804841afd
Autor:
Jesse V Jokerst, Zuxiong Chen, Lingyun Xu, Rosalie Nolley, Edwin Chang, Breeana Mitchell, James D Brooks, Sanjiv S Gambhir
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139484 (2015)
Novel biomarker assays and upgraded analytical tools are urgently needed to accurately discriminate benign prostatic hypertrophy (BPH) from prostate cancer (CaP). To address this unmet clinical need, we report a piezeoelectric/magnetic bead-based ass
Externí odkaz:
https://doaj.org/article/ad37474499ad485187cf59177cad8806
Autor:
Hermann B Frieboes, Bryan R Smith, Yao-Li Chuang, Ken Ito, Allison M Roettgers, Sanjiv S Gambhir, Vittorio Cristini
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 3, p e1003008 (2013)
Non-Hodgkin's lymphoma is a disseminated, highly malignant cancer, with resistance to drug treatment based on molecular- and tissue-scale characteristics that are intricately linked. A critical element of molecular resistance has been traced to the l
Externí odkaz:
https://doaj.org/article/ed2a890d2776402589672a8070e89bea
Autor:
Viswam S Nair, Khun Visith Keu, Madelyn S Luttgen, Anand Kolatkar, Minal Vasanawala, Ware Kuschner, Kelly Bethel, Andrei H Iagaru, Carl Hoh, Joseph B Shrager, Billy W Loo, Lyudmila Bazhenova, Jorge Nieva, Sanjiv S Gambhir, Peter Kuhn
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67733 (2013)
We investigated the relationship of circulating tumor cells (CTCs) in non-small cell lung cancer (NSCLC) with tumor glucose metabolism as defined by (18)F-fluorodeoxyglucose (FDG) uptake since both have been associated with patient prognosis.We perfo
Externí odkaz:
https://doaj.org/article/ed62207e39ea4b5abcb0a71f8ab28bb7
Autor:
Xinrui Yan, Pritha Ray, Ramasamy Paulmurugan, Ricky Tong, Yongquan Gong, Ataya Sathirachinda, Joseph C Wu, Sanjiv S Gambhir
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e73580 (2013)
Transgenic mouse with a stably integrated reporter gene(s) can be a valuable resource for obtaining uniformly labeled stem cells, tissues, and organs for various applications. We have generated a transgenic mouse model that ubiquitously expresses a t
Externí odkaz:
https://doaj.org/article/d3b063870ee040fb868f949e6c15bf21