Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sanjib Karki"'
Autor:
Xue Jiang, Zhihui Zhu, Haiyan Qin, Priyanka Tripathi, Liansheng Zhong, Ahmed Elsherbini, Sanjib Karki, Simone M. Crivelli, Wenbo Zhi, Guanghu Wang, Stefanka D. Spassieva, Erhard Bieberich
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Ceramide-rich platforms (CRPs) mediate association of proteins with the sphingolipid ceramide and may regulate protein interaction in membrane contact sites to the cytoskeleton, organelles, and infectious pathogens. However, visualization of ceramide
Externí odkaz:
https://doaj.org/article/e785207524be4ff8905dc698f262b049
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1870:140817
Three decades of research, both in vitro and in vivo, have demonstrated the conformational heterogeneity that is displayed by the amyloid β peptide (Aβ) in Alzheimer's disease (AD). Understanding the distinct properties between Aβ conformations an
Autor:
Kendra L. Puig, Keiko Rausch, Joshua A. Kulas, Brett A. McGregor, Lalida Rojanathammanee, Angela M. Floden, Colin K. Combs, Gunjan D. Manocha, Sanjib Karki, James E. Porter, Kelley R. Puig, Michael R. Nichols, Diane C. Darland
Publikováno v:
Journal of Neuroscience. 36:8471-8486
Prior work suggests that amyloid precursor protein (APP) can function as a proinflammatory receptor on immune cells, such as monocytes and microglia. Therefore, we hypothesized that APP serves this function in microglia during Alzheimer9s disease. Al
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1834:65-70
Accumulation of aggregated amyloid-β protein (Aβ) is an important feature of Alzheimer’s disease. There is significant interest in understanding the initial steps of Aβ aggregation due to the recent focus on soluble Aβ oligomers. In vitro studi
Autor:
Sanjib Karki, Michael R. Nichols
Neuroinflammation triggered by accumulation of amyloid-β protein (Aβ) is a significant component of the Alzheimer's disease (AD) brain. Senile plaques composed of Aβ attract and activate microglia cells resulting in cytokine secretion and a proinf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691337ac8c4c29fe12d4b962a4670285
https://europepmc.org/articles/PMC4312186/
https://europepmc.org/articles/PMC4312186/